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View Structure Prediction Details

Protein: Tf2-1, Tf2-4, Tf...
Organism: Schizosaccharomyces pombe
Length: 1333 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Tf2-1, Tf2-4, Tf....

Description E-value Query
Range		 Subject
Range
gi|77553962 - gi|77553962|gb|ABA96758.1| retrotransposon protein, putative, Ty3-gypsy subclass [Oryza sativa (japo...
 1326.0 [0..33] [1317..395]
gi|116308831 - gi|116308831|emb|CAH65969.1| H0820C10.2 [Oryza sativa (indica cultivar-group)]
 1323.0 [0..33] [1317..314]

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Predicted Domain #1
Region A:
Residues: [1-126] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYANYRYMK ARAKRWRPEN LDGIQTSDEH LINLFAKILS KHVPEIGKFD PNKDVESYIS  60
   61 KLDQHFTEYP SLFPNEHTKR QYTLNHLEEL EQQFAERMFS ENGSLTWQEL LRQTGKVQGS 120
  121 NKGDRL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1bajA
Description: HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.28448955239851 bayes_pls_golite062009
transcription regulator activity 0.786413651497179 bayes_pls_golite062009
nucleic acid binding 0.548058390008807 bayes_pls_golite062009
DNA binding 0.541861348095563 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [127-194] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKTFEGFRNQ LDKVQFIRKL MSKANVDDFH TRLFILWMLP YSLRKLKERN YWKSEISEIY  60
   61 DFLEDKRT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1a1tA
Description: HIV nucleocapsid
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [195-392] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASYGKTHKRF QLQNKNLGKE SLSKKNNTTN SRNLRKTNVS RIEYSSNKFL NHTRKRYEMV  60
   61 LQAELPDFKC SIPCLIDTGA QANIITEETV RAHKLPTRPW SKSVIYGGVY PNKINRKTIK 120
  121 LNISLNGISI KTEFLVVKKF SHPAAISFTT LYDNNIEISS SKHTLSQMNK VSNIVKEPEL 180
  181 PDIYKEFKDI TAETNTEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1hvcA
Description: CRYSTAL STRUCTURE OF A TETHERED DIMER OF HIV-1 PROTEASE COMPLEXED WITH AN INHIBITOR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 0.934096653248474 bayes_pls_golite062009
catalytic activity 0.778715931979077 bayes_pls_golite062009
endopeptidase activity 0.478344177019014 bayes_pls_golite062009
peptidase activity 0.476168407632189 bayes_pls_golite062009
aspartic-type endopeptidase activity 0.403642706513097 bayes_pls_golite062009
aspartic-type peptidase activity 0.403642706513097 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.229854266530628 bayes_pls_golite062009
binding 0.151374799700247 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [393-920] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPKPIKGLEF EVELTQENYR LPIRNYPLPP GKMQAMNDEI NQGLKSGIIR ESKAINACPV  60
   61 MFVPKKEGTL RMVVDYKPLN KYVKPNIYPL PLIEQLLAKI QGSTIFTKLD LKSAYHLIRV 120
  121 RKGDEHKLAF RCPRGVFEYL VMPYGISTAP AHFQYFINTI LGEAKESHVV CYMDDILIHS 180
  181 KSESEHVKHV KDVLQKLKNA NLIINQAKCE FHQSQVKFIG YHISEKGFTP CQENIDKVLQ 240
  241 WKQPKNRKEL RQFLGSVNYL RKFIPKTSQL THPLNNLLKK DVRWKWTPTQ TQAIENIKQC 300
  301 LVSPPVLRHF DFSKKILLET DASDVAVGAV LSQKHDDDKY YPVGYYSAKM SKAQLNYSVS 360
  361 DKEMLAIIKS LKHWRHYLES TIEPFKILTD HRNLIGRITN ESEPENKRLA RWQLFLQDFN 420
  421 FEINYRPGSA NHIADALSRI VDETEPIPKD SEDNSINFVN QISITDDFKN QVVTEYTNDT 480
  481 KLLNLLNNED KRVEENIQLK DGLLINSKDQ ILLPNDTQLT RTIIKKYH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 164.0
Match: 1lw0A
Description: HIV RNase H (Domain of reverse transcriptase); HIV-1 reverse transcriptase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleotidyltransferase activity 1.11992657762408 bayes_pls_golite062009
DNA polymerase activity 0.97735803396704 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.966025256970563 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.870949824174184 bayes_pls_golite062009
binding 0.452590422306309 bayes_pls_golite062009
catalytic activity 0.282562363863898 bayes_pls_golite062009
transferase activity 0.280309374132814 bayes_pls_golite062009
ribonuclease activity 0.164715045017202 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [921-1220] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEGKLIHPGI ELLTNIILRR FTWKGIRKQI QEYVQNCHTC QINKSRNHKP YGPLQPIPPS  60
   61 ERPWESLSMD FITALPESSG YNALFVVVDR FSKMAILVPC TKSITAEQTA RMFDQRVIAY 120
  121 FGNPKEIIAD NDHIFTSQTW KDFAHKYNFV MKFSLPYRPQ TDGQTERTNQ TVEKLLRCVC 180
  181 STHPNTWVDH ISLVQQSYNN AIHSATQMTP FEIVHRYSPA LSPLELPSFS DKTDENSQET 240
  241 IQVFQTVKEH LNTNNIKMKK YFDMKIQEIE EFQPGDLVMV KRTKTGFLHK SNKLAPSFAG 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.30103
Match: 1k6yA
Description: N-terminal Zn binding domain of HIV integrase; Retroviral integrase, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.485910322334531 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [1221-1333] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFYVLQKSGP NNYELDLPDS IKHMFSSTFH VSHLEKYRHN SELNYATIDE SDIGTILHIL  60
   61 EHKNREQVLY LNVKYISNLN PSTIMSGWTT LATALQADKA IVNDYIKNNN LNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 2dntA
Description: No description for 2dntA was found.
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