| Protein: | hos2 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 434 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hos2.
| Description | E-value | Query Range |
Subject Range |
|
|
553.0 | [0..24] | [430..7] |
|
|
548.0 | [0..21] | [432..4] |
|
|
544.0 | [0..24] | [409..7] |
|
|
544.0 | [0..24] | [408..7] |
|
|
544.0 | [0..24] | [408..7] |
|
|
544.0 | [0..24] | [408..7] |
|
Region A: Residues: [1-434] |
1 11 21 31 41 51
| | | | | |
1 MDTPETSTPY EQVEKGSFFS FRPQKKRVTY HLDEQVGNYH YGDKHPMKPH RITITNHLVM 60
61 GYGLHNKMSV FSPRMATFGE MSEFHREDYL DFLKRVTPDN AEQFADKFQQ FNIGDDCPVF 120
121 DGTYEFSQRS AGASLDASRK LVQGQTDIAI NWSGGLHHAK RGEASGFCYV NDIVLAILNM 180
181 LRFFPRVLYI DIDIHHGDGV QQAFYESDRV LTVSFHKYNG DFFPATGNFD ENGVKGGKYF 240
241 ALNVPLEDGI GDEQYTSLFK SIIEPTINTF QPSAIVLQCG ADSLGYDRLG VFNLSIHAHG 300
301 ECVRFTRSFN IPMLVVGGGG YTLRNVARAW CYETSICVNE QIPSELPRET LYYEFFAPDY 360
361 TLHPRLTTKI ENKNTPKALE DLRIRALEQL RYLGGAPSVQ MQQIPPDLTG HLEEEDERLN 420
421 DEYLDKAVDV RVRG
|
| Detection Method: |  |
| Confidence: | 102.0 |
| Match: | 1t64A |
| Description: | Crystal Structure of human HDAC8 complexed with Trichostatin A |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein deacetylase activity | 12.8220438463909 | bayes_pls_golite062009 |
| histone deacetylase activity | 12.6231784270509 | bayes_pls_golite062009 |
| deacetylase activity | 11.5037545953213 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 9.39837596691907 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K16 specific) | 6.99181745976945 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 5.91624581343504 | bayes_pls_golite062009 |
| agmatinase activity | 3.73238467801147 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K9 specific) | 3.65015413158247 | bayes_pls_golite062009 |
| transcription repressor activity | 3.49362347258099 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K14 specific) | 3.25708078682827 | bayes_pls_golite062009 |
| transcription regulator activity | 3.05701986980927 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K27 specific) | 2.60243126690148 | bayes_pls_golite062009 |
| hydrolase activity | 2.48411098726406 | bayes_pls_golite062009 |
| transcription factor binding | 2.19991964087943 | bayes_pls_golite062009 |
| NAD-independent histone deacetylase activity | 2.1026758793482 | bayes_pls_golite062009 |
| nucleic acid binding | 2.09632179671955 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.98907367314887 | bayes_pls_golite062009 |
| DNA binding | 1.982290944939 | bayes_pls_golite062009 |
| binding | 1.948738669065 | bayes_pls_golite062009 |
| protein binding | 1.77599011146146 | bayes_pls_golite062009 |
| catalytic activity | 1.68836803454021 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K9 specific) | 1.48241147541212 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 1.37118634909958 | bayes_pls_golite062009 |
| transcription activator activity | 1.31578100431097 | bayes_pls_golite062009 |
| transcription factor activity | 1.24596588472933 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | 1.01223037319069 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84972377395539 | bayes_pls_golite062009 |
| histone methyltransferase activity | 0.396822865624511 | bayes_pls_golite062009 |
| transferase activity | 0.323230424038105 | bayes_pls_golite062009 |
| chromatin binding | 0.104097933861351 | bayes_pls_golite062009 |
