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View Structure Prediction Details

Protein: nup61
Organism: Schizosaccharomyces pombe
Length: 565 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nup61.

Description E-value Query
Range
Subject
Range
gi|73969988 - gi|73969988|ref|XP_531768.2| PREDICTED: similar to RAN-binding protein 2-like 1 isoform 1 [Canis fam...
220.0 [0..246] [565..1109]
gi|113412933 - gi|113412933|ref|XP_001134114.1| PREDICTED: similar to RANBP2-like and GRIP domain containing 2 isof...
215.0 [0..246] [565..1115]
gi|114579429 - gi|114579429|ref|XP_001138683.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
212.0 [0..246] [565..1133]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRGADHQL TKDQDDSDDD RHGPVEVPKE ASADVMATRK IAKPKSRKRP TSGVSSPGIF  60
   61 ANLAAKPVSL PASTTQFTFG KPAVTANNDS DIHLKKRGLN KSFIDAVIKS VDNNPFGNLS 120
  121 PLFDEYRQHF SSIEKKPAEG NAFIVSTSFL SNVFLEQPTS NAVVSE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [167-343]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNPQQQKSQD SSSFVTEKPA SSEKEDKEKP LVPPGAPRFG FSAPALGSSF QFNSSAFTPK  60
   61 GSFGEKSATE AEAKEKETSS NQTATGTAAT TTNQFSFNTA ANPFAFAKKE NEESKPLTPV 120
  121 FSFSTTMASA DASKETKQTH ETKDSKSEES KPSNNEKSEN AVEPAKGNTM SFSWTPD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [344-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPIKFDTPEK KFTFTNPLSS KKLPASSDVK PPSAAAVGFS FGTTTNPFSF AAPKSSFPTS  60
   61 STPASVGAEK SEETSNGNKS EQEEKENGND E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [435-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRSNDSLVSG KGKGEENEDS VFETRAKIYR FDATSKSYSD IGIGPLKINV DRDTGSARIL  60
   61 ARVEGSGKLL LNVRLCQDFE YSLAGKKDVK VPAASTDGKS IEMYLIRVKE PSTAEKLLAE 120
  121 LNEKKVSKSE N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1rrpB
Description: Nuclear pore complex protein Nup358
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.29080729281876 bayes_pls_golite062009
protein binding 2.12168271674167 bayes_pls_golite062009
transporter activity 1.28986800087234 bayes_pls_golite062009
molecular transducer activity 1.15625292719687 bayes_pls_golite062009
signal transducer activity 1.15625292719687 bayes_pls_golite062009
Ran GTPase binding 1.07023555877478 bayes_pls_golite062009
substrate-specific transporter activity 0.79883446648737 bayes_pls_golite062009
cytoskeletal protein binding 0.74133713912741 bayes_pls_golite062009
actin binding 0.57235223545021 bayes_pls_golite062009
receptor activity 0.369903612832044 bayes_pls_golite062009
transcription regulator activity 0.324566338715835 bayes_pls_golite062009
protein domain specific binding 0.18356841109571 bayes_pls_golite062009
transmembrane receptor activity 0.159652062741581 bayes_pls_golite062009
DNA binding 0.136435190086451 bayes_pls_golite062009
nucleic acid binding 0.118897432176337 bayes_pls_golite062009
pyrophosphatase activity 0.0611639610381174 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0524559849408587 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0498422520006935 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle