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View Structure Prediction Details

Protein: nup61
Organism: Schizosaccharomyces pombe
Length: 565 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nup61.

Description E-value Query
Range
Subject
Range
gi|73969988 - gi|73969988|ref|XP_531768.2| PREDICTED: similar to RAN-binding protein 2-like 1 isoform 1 [Canis fam...
220.0 [0..246] [565..1109]
gi|113412933 - gi|113412933|ref|XP_001134114.1| PREDICTED: similar to RANBP2-like and GRIP domain containing 2 isof...
215.0 [0..246] [565..1115]
gi|114579429 - gi|114579429|ref|XP_001138683.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
212.0 [0..246] [565..1133]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRGADHQL TKDQDDSDDD RHGPVEVPKE ASADVMATRK IAKPKSRKRP TSGVSSPGIF  60
   61 ANLAAKPVSL PASTTQFTFG KPAVTANNDS DIHLKKRGLN KSFIDAVIKS VDNNPFGNLS 120
  121 PLFDEYRQHF SSIEKKPAEG NAFIVSTSFL SNVFLEQPTS NAVVSE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [167-343]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNPQQQKSQD SSSFVTEKPA SSEKEDKEKP LVPPGAPRFG FSAPALGSSF QFNSSAFTPK  60
   61 GSFGEKSATE AEAKEKETSS NQTATGTAAT TTNQFSFNTA ANPFAFAKKE NEESKPLTPV 120
  121 FSFSTTMASA DASKETKQTH ETKDSKSEES KPSNNEKSEN AVEPAKGNTM SFSWTPD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [344-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPIKFDTPEK KFTFTNPLSS KKLPASSDVK PPSAAAVGFS FGTTTNPFSF AAPKSSFPTS  60
   61 STPASVGAEK SEETSNGNKS EQEEKENGND E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [435-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRSNDSLVSG KGKGEENEDS VFETRAKIYR FDATSKSYSD IGIGPLKINV DRDTGSARIL  60
   61 ARVEGSGKLL LNVRLCQDFE YSLAGKKDVK VPAASTDGKS IEMYLIRVKE PSTAEKLLAE 120
  121 LNEKKVSKSE N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1rrpB
Description: Nuclear pore complex protein Nup358
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.29080729281876 bayes_pls_golite062009
protein binding 2.12168271674167 bayes_pls_golite062009
transporter activity 1.28986800087234 bayes_pls_golite062009
molecular transducer activity 1.15625292719687 bayes_pls_golite062009
signal transducer activity 1.15625292719687 bayes_pls_golite062009
Ran GTPase binding 1.07023555877478 bayes_pls_golite062009
substrate-specific transporter activity 0.79883446648737 bayes_pls_golite062009
cytoskeletal protein binding 0.74133713912741 bayes_pls_golite062009
actin binding 0.57235223545021 bayes_pls_golite062009
receptor activity 0.369903612832044 bayes_pls_golite062009
transcription regulator activity 0.324566338715835 bayes_pls_golite062009
protein domain specific binding 0.18356841109571 bayes_pls_golite062009
transmembrane receptor activity 0.159652062741581 bayes_pls_golite062009
DNA binding 0.136435190086451 bayes_pls_golite062009
nucleic acid binding 0.118897432176337 bayes_pls_golite062009
pyrophosphatase activity 0.0611639610381174 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0524559849408587 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0498422520006935 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle