YRC Public Data Repository - Protein Structure Prediction

Protein:	csn71
Organism:	Schizosaccharomyces pombe
Length:	205 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for csn71.

Description	E-value	Query Range	Subject Range
gi\|109095310 - gi\|109095310\|ref\|XP_001108483.1\| PREDICTED: COP9 constitutive photomorphogenic homolog subunit 7A (A...	182.0	[0..1]	[188..27]
gi\|114643097 - gi\|114643097\|ref\|XP_001162694.1\| PREDICTED: COP9 complex subunit 7a isoform 1 [Pan troglodytes]	180.0	[0..1]	[188..27]
gi\|68383150, gi\|... - gi\|68383150\|ref\|XP_697387.1\| PREDICTED: similar to Cops7a protein [Danio rerio], gi\|68383144\|ref\|XP_...	180.0	[0..1]	[191..64]
gi\|109487451, gi... - gi\|62655356\|ref\|XP_343615.2\| PREDICTED: similar to COP9 (constitutive photomorphogenic) homolog, sub...	178.0	[0..1]	[188..85]
gi\|108868614, gi... - gi\|157107902\|ref\|XP_001649990.1\| 26S proteasome subunit [Aedes aegypti], gi\|108868614\|gb\|EAT32839.1\|...	178.0	[0..4]	[174..204]
gi\|47221554 - gi\|47221554\|emb\|CAF97819.1\| unnamed protein product [Tetraodon nigroviridis]	177.0	[0..1]	[191..14]
gi\|125526148 - gi\|125526148\|gb\|EAY74262.1\| hypothetical protein OsI_02152 [Oryza sativa Indica Group] gi\|34914614, gi\|... - gi\|34914614\|ref\|NP_918654.1\| putative 26S proteasome subunit [Oryza sativa (japonica cultivar-group)...	176.0	[0..3]	[173..203]
CSN7A_MOUSE - COP9 signalosome complex subunit 7a OS=Mus musculus GN=Cops7a PE=1 SV=2	176.0	[0..1]	[191..27]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEKISQAID DPNVFCFQEL WIECQEVQKS QPIDSAVLRT LEIFCRGDIR DASSEWNELR  60
   61 FKKLRLLTLI DLANRHVGSS VSFETILVHL QLDRLPPSDP TFTVEYYIMQ AMMNQILVGK 120
  121 INAKTQTLHV SWALERFLDS KRIDEMKYSL DRFIERCSNI LFQLDAGTPS VSKSFKRASR 180
  181 MSSSDGIDYM VFDKRPRPDD TDFDL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.35
Match:	1ufmA
Description:	Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.44650475502011	bayes_pls_golite062009
DNA binding	4.14600429789206	bayes_pls_golite062009
nucleic acid binding	4.04917149323679	bayes_pls_golite062009
transcription factor activity	3.4813422326469	bayes_pls_golite062009
binding	3.37660003833383	bayes_pls_golite062009
sequence-specific DNA binding	1.96682762098646	bayes_pls_golite062009
transcription activator activity	1.81076806553342	bayes_pls_golite062009
transcription repressor activity	1.68338035958948	bayes_pls_golite062009
small conjugating protein ligase activity	1.28416365596732	bayes_pls_golite062009
ubiquitin-protein ligase activity	1.12766532785895	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.04169645404432	bayes_pls_golite062009
acid-amino acid ligase activity	0.761838897494019	bayes_pls_golite062009
protein binding	0.726445167461826	bayes_pls_golite062009
transcription factor binding	0.507503949885045	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.49516964123412	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.281229260644949	bayes_pls_golite062009
hydrolase activity	0.20695163916851	bayes_pls_golite062009
transferase activity	0.10058871838551	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: