| Protein: | clr6 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 405 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for clr6.
| Description | E-value | Query Range |
Subject Range |
|
|
565.0 | [0..2] | [405..5] |
|
|
558.0 | [0..1] | [387..4] |
|
|
556.0 | [0..3] | [405..6] |
|
|
554.0 | [0..2] | [405..3] |
|
|
554.0 | [0..2] | [386..5] |
|
|
553.0 | [0..2] | [386..5] |
|
Region A: Residues: [1-405] |
1 11 21 31 41 51
| | | | | |
1 MGFGKKKVSY FYDEDVGNYH YGPQHPMKPH RVRMVHNLVV NYNLYEKLNV ITPVRATRND 60
61 MTRCHTDEYI EFLWRVTPDT MEKFQPHQLK FNVGDDCPVF DGLYEFCSIS AGGSIGAAQE 120
121 LNSGNAEIAI NWAGGLHHAK KREASGFCYV NDIALAALEL LKYHQRVLYI DIDVHHGDGV 180
181 EEFFYTTDRV MTCSFHKFGE YFPGTGHIKD TGIGTGKNYA VNVPLRDGID DESYESVFKP 240
241 VISHIMQWFR PEAVILQCGT DSLAGDRLGC FNLSMKGHSM CVDFVKSFNL PMICVGGGGY 300
301 TVRNVARVWT YETGLLAGEE LDENLPYNDY LQYYGPDYKL NVLSNNMENH NTRQYLDSIT 360
361 SEIIENLRNL SFAPSVQMHK TPGDFTFENA EKQNIAKEEI MDERV
|
| Detection Method: |  |
| Confidence: | 102.0 |
| Match: | 1t64A |
| Description: | Crystal Structure of human HDAC8 complexed with Trichostatin A |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein deacetylase activity | 12.8220438463909 | bayes_pls_golite062009 |
| histone deacetylase activity | 12.6231784270509 | bayes_pls_golite062009 |
| deacetylase activity | 11.5037545953213 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 9.39837596691907 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K16 specific) | 6.99181745976945 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 5.91624581343504 | bayes_pls_golite062009 |
| agmatinase activity | 3.73238467801147 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K9 specific) | 3.65015413158247 | bayes_pls_golite062009 |
| transcription repressor activity | 3.49362347258099 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K14 specific) | 3.25708078682827 | bayes_pls_golite062009 |
| transcription regulator activity | 3.05701986980927 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K27 specific) | 2.60243126690148 | bayes_pls_golite062009 |
| hydrolase activity | 2.48411098726406 | bayes_pls_golite062009 |
| transcription factor binding | 2.19991964087943 | bayes_pls_golite062009 |
| NAD-independent histone deacetylase activity | 2.1026758793482 | bayes_pls_golite062009 |
| nucleic acid binding | 2.09632179671955 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.98907367314887 | bayes_pls_golite062009 |
| DNA binding | 1.982290944939 | bayes_pls_golite062009 |
| binding | 1.948738669065 | bayes_pls_golite062009 |
| protein binding | 1.77599011146146 | bayes_pls_golite062009 |
| catalytic activity | 1.68836803454021 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K9 specific) | 1.48241147541212 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 1.37118634909958 | bayes_pls_golite062009 |
| arginase activity | 1.34373529002692 | bayes_pls_golite062009 |
| transcription activator activity | 1.31578100431097 | bayes_pls_golite062009 |
| transcription factor activity | 1.24596588472933 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | 1.01223037319069 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84972377395539 | bayes_pls_golite062009 |
| histone methyltransferase activity | 0.396822865624511 | bayes_pls_golite062009 |
| transferase activity | 0.323230424038105 | bayes_pls_golite062009 |
| chromatin binding | 0.104097933861351 | bayes_pls_golite062009 |
