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View Structure Prediction Details

Protein: Rrp45-PA, FBpp03...
Organism: Drosophila melanogaster
Length: 412 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rrp45-PA, FBpp03....

Description E-value Query
Range
Subject
Range
gi|89350148, gi|... - gi|89361251|ref|ZP_01199067.1| RNA binding S1:KH [Xanthobacter autotrophicus Py2], gi|89350148|gb|EA...
365.0 [0..3] [412..344]

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Predicted Domain #1
Region A:
Residues: [1-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFHNSNFFEP GKSKPERSFV QLAVKQNQRL DGRRSNESRD VELTFGKDWG SVAVSMGDTK  60
   61 VLAQVTCEMG PPALSRPNEG KIHLNVYLGG VAFLDEAHTT HDQRSLKLNS LLERTFRSSR 120
  121 SIDLESLCVA VEKHVWCIRV NVNVLNHDGN LYDASTIATL AALMHFRRPD VWYKDGELRI 180
  181 FKKKEREFIP LLFHHYPVSV TYCVYKSSVQ PILDPTLLEE NAADSVIVLS FNSFQELCSL 240
  241 TAGGTAPTNA RIIMQCARNA AVRCKSLLNF VRKALALDEE CRSQGDQSVD GLVALILNTE 300
  301 HKLSYNKLMG RQKQEQQPPP SEKMQLDNNE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.522879
Match: 2nn6A
Description: No description for 2nn6A was found.

Predicted functions:

Term Confidence Notes
exoribonuclease activity 7.55877202113513 bayes_pls_golite062009
ribonuclease activity 7.54644729272203 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 7.5310318714913 bayes_pls_golite062009
3'-5'-exoribonuclease activity 6.46930372693262 bayes_pls_golite062009
3'-5' exonuclease activity 4.29895100594643 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3.83939403332553 bayes_pls_golite062009
exonuclease activity 3.40686901061667 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.86434572018929 bayes_pls_golite062009
RNA binding 2.05527376734941 bayes_pls_golite062009
structural constituent of ribosome 1.90115575554186 bayes_pls_golite062009
structural molecule activity 1.69321127364043 bayes_pls_golite062009
hydrolase activity 1.55476709794855 bayes_pls_golite062009
transcription regulator activity 1.20748032530392 bayes_pls_golite062009
mRNA binding 1.17402119891853 bayes_pls_golite062009
nucleic acid binding 1.05662964529454 bayes_pls_golite062009
binding 0.907487229190259 bayes_pls_golite062009
catalytic activity 0.878454819018611 bayes_pls_golite062009
DNA binding 0.828609700556836 bayes_pls_golite062009
nuclease activity 0.69721312877891 bayes_pls_golite062009
carbohydrate kinase activity 0.51810239718467 bayes_pls_golite062009
tRNA-specific ribonuclease activity 0.383567539949931 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0287026367466632 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [331-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSETPVANEE PSKEESAGAP MDTSDWLPHD EDSQELPMRS EASPSKAGLK GKQSRGKYKA  60
   61 NKKTPPRKQN HSDSEEEAKR YI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.69897
Match: 1sroA
Description: S1 RNA BINDING DOMAIN, NMR, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 7.42330864261751 bayes_pls_golite062009
exoribonuclease activity 6.76241588209982 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 6.73428326869965 bayes_pls_golite062009
3'-5'-exoribonuclease activity 5.13367897180134 bayes_pls_golite062009
3'-5' exonuclease activity 3.51306349336452 bayes_pls_golite062009
nucleic acid binding 3.194200758646 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3.07263153665399 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.73968547121328 bayes_pls_golite062009
DNA binding 2.71213098011194 bayes_pls_golite062009
exonuclease activity 2.66053639652924 bayes_pls_golite062009
RNA binding 2.41160981373213 bayes_pls_golite062009
binding 2.24181355929217 bayes_pls_golite062009
structural constituent of ribosome 2.02605441840546 bayes_pls_golite062009
structure-specific DNA binding 1.81524862921454 bayes_pls_golite062009
structural molecule activity 1.81283970647925 bayes_pls_golite062009
single-stranded DNA binding 1.62996999055328 bayes_pls_golite062009
1.5765009871268 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 1.35850109411274 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 1.35845277283398 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 1.35845277283398 bayes_pls_golite062009
exoribonuclease II activity 1.18248519339188 bayes_pls_golite062009
transcription regulator activity 0.996884322431837 bayes_pls_golite062009
hydrolase activity 0.724860465280978 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
mRNA binding 0.4162128308402 bayes_pls_golite062009
ligase activity 0.346041081217685 bayes_pls_golite062009
sequence-specific DNA binding 0.32084431704638 bayes_pls_golite062009
transcription factor activity 0.298729064067577 bayes_pls_golite062009
translation regulator activity 0.22908707234671 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.179682348023561 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.151650064901878 bayes_pls_golite062009
translation initiation factor activity 0.11625379846973 bayes_pls_golite062009
RNA polymerase activity 0.0740938021136293 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.0740938021136293 bayes_pls_golite062009

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