| Protein: | Fur2-PA, Fur2-PB... |
| Organism: | Drosophila melanogaster |
| Length: | 1682 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Fur2-PA, Fur2-PB....
| Description | E-value | Query Range |
Subject Range |
|
|
1366.0 | [0..1] | [1682..1] |
|
Region A: Residues: [1-214] |
1 11 21 31 41 51
| | | | | |
1 MSNTTRSSRV TIGRIGTTPQ ITDPWSSGLE KQRPSRCGGP KSLAEPTYRK IGRRKMMLHM 60
61 RVHDPGTTVT QRAKETATAK LNRIYLCTFN RMAQSCIYFV LFLVILSPNT SCALRSSAGE 120
121 TQNYVGILSN DSATTTYDVS SLHSSRRTNP PSSSSSSSSN VDVDYRNDRE LHKVDLVGLG 180
181 GERAGQAETI SGGKYDYNYE NTHTNASAKD EIVE
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [215-326] |
1 11 21 31 41 51
| | | | | |
1 RQSNSLDFDG VDMFGAFSIP EEAIYTNEFA VNIPAGKQMA DVIATKHGFI NRGQIGSLDN 60
61 YYLFQHHHVS KRSLRSSRKH QGALKSENEV KWMQQQHEKV RRKRDGPYQD LP
|
| Detection Method: | |
| Confidence: | 23.0 |
| Match: | 1kn6A |
| Description: | Prohormone convertase 1 pro-domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [327-369] |
1 11 21 31 41 51
| | | | | |
1 TYSPYNLLRQ HGGYVVDPNP HLSFSPESIS LASHSQRMEY RDV
|
| Detection Method: | |
| Confidence: | 58.522879 |
| Match: | 2e1pA |
| Description: | No description for 2e1pA was found. |
|
Region A: Residues: [370-832] |
1 11 21 31 41 51
| | | | | |
1 SSHFIFPDPL FKEQWYLVSK NGGAKDGLDM NVGPAWQKGY TGKGVVVSIL DDGIQTNHPD 60
61 LAQNYDPEAS FDINGNDSDP TPQDNGDNKH GTRCAGEVAA VAFNNFCGVG VAYNASIGGV 120
121 RMLDGKVNDV VEAQALSLNP SHIDIYSASW GPEDDGSTVD GPGPLARRAF IYGVTSGRQG 180
181 KGSIFVWASG NGGRYTDSCN CDGYTNSIFT LSISSATQAG FKPWYLEECS STLATTYSSG 240
241 TPGHDKSVAT VDMDGSLRPD HICTVEHTGT SASAPLAAGI CALALEANPE LTWRDMQYLV 300
301 VYTSRPAPLE KENGWTLNGV KRKYSHKFGY GLMDAGAMVS LAEQWTSVPP QHICKSRENN 360
361 EDRKIDGAYG STLSTHMDVN GCAGTINEVR YLEHVQCRIT LRFFPRGNLR ILLTSPMGTT 420
421 STLLFERPRD IVKSNFDDWP FLSVHFWGEK AEGRWTLQVI NGG
|
| Detection Method: | |
| Confidence: | 161.0 |
| Match: | 1p8jA |
| Description: | Furin, C-terminal domain; Furin, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 4.77677490610016 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 4.40501322467328 | bayes_pls_golite062009 |
| serine hydrolase activity | 4.30899317351154 | bayes_pls_golite062009 |
| serine-type peptidase activity | 4.29545891350519 | bayes_pls_golite062009 |
| nerve growth factor binding | 4.00876127913772 | bayes_pls_golite062009 |
| endopeptidase activity | 3.83336601331518 | bayes_pls_golite062009 |
| serine-type endopeptidase activity | 3.71508033196614 | bayes_pls_golite062009 |
| growth factor binding | 2.60157910925561 | bayes_pls_golite062009 |
| hydrolase activity | 2.05732080397524 | bayes_pls_golite062009 |
| neurotrophin binding | 1.71684037453881 | bayes_pls_golite062009 |
| receptor binding | 1.53429624476134 | bayes_pls_golite062009 |
| eukaryotic cell surface binding | 1.50287724152407 | bayes_pls_golite062009 |
| binding | 1.28749522568113 | bayes_pls_golite062009 |
| catalytic activity | 0.597535457699629 | bayes_pls_golite062009 |
| peptide binding | 0.567438185669089 | bayes_pls_golite062009 |
| protein binding | 0.480761501301928 | bayes_pls_golite062009 |
| exopeptidase activity | 0.42083764849682 | bayes_pls_golite062009 |
| low-density lipoprotein receptor binding | 0.367152941142039 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.22219445619715 | bayes_pls_golite062009 |
| lipoprotein receptor binding | 0.21778182396266 | bayes_pls_golite062009 |
|
Region A: Residues: [833-896] |
1 11 21 31 41 51
| | | | | |
1 RRRVNQPGIL SKWQLIFYGT STQPMRLKSE LLNSSPQLRS PSSSNPFLFP SASNIGQPAN 60
61 EGGN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [897-1426] |
1 11 21 31 41 51
| | | | | |
1 FNTDSFASYL NYQNIFSSAG SDPEPATATL DGQNVTAAIA GGSSAESLGF TASAAQLVAA 60
61 PETRDGDKKI LHSCDAECDS SGCYGRGPTQ CVACSHYRLD NTCVSRCPPR SFPNQVGICW 120
121 PCHDTCETCA GAGPDSCLTC APAHLHVIDL AVCLQFCPDG YFENSRNRTC VPCEPNCASC 180
181 QDHPEYCTSC DHHLVMHEHK CYSACPLDTY ETEDNKCAFC HSTCATCNGP TDQDCITCRS 240
241 SRYAWQNKCL ISCPDGFYAD KKRLECMPCQ EGCKTCTSNG VCSECLQNWT LNKRDKCIVS 300
301 GSEGCSESEF YSQVEGQCRP CHASCGSCNG PADTSCTSCP PNRLLEQSRC VSGCREGFFV 360
361 EAGSLCSPCL HTCSQCVSRT NCSNCSKGLE LQNGECRTTC ADGYYSDRGI CAKCYLSCHT 420
421 CSGPRRNQCV QCPAGWQLAA GECHPECPEG FYKSDFGCQK CHHYCKTCND AGPLACTSCP 480
481 PHSMLDGGLC MECLSSQYYD TTSATCKTCH DSCRSCFGPG QFSCKGCVPP
|
| Detection Method: | |
| Confidence: | 11.154902 |
| Match: | 2ahxA |
| Description: | Crystal structure of ErbB4/HER4 extracellular domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1427-1581] |
1 11 21 31 41 51
| | | | | |
1 LHLDQLNSQC VSCCQNQTLA EKTSSAACCN CDGETGECKA TSTGGKRRTV VGSGSAYKSS 60
61 ESKHGSFEND GNAREFVLRL DSPLTAITAI AVAICLLIIT IFSIIFAVLQ RNSNHVSRNS 120
121 VRYRKIANTS SGRRKNLSAK PTSDARFIFN IGEDD
|
| Detection Method: | |
| Confidence: | 7.522879 |
| Match: | 1yo8A |
| Description: | Strucuture of the C-terminal domain of human thrombospondin-2 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1582-1682] |
1 11 21 31 41 51
| | | | | |
1 DTDGDNSDDE LDGNVGTDIN NRIVYDRKGN DHGHEFYIES TNDIDAIEFH CNGAGAQKAE 60
61 TQLQRCNANG DDDDILHYDR HTNAERKNHP SSTTSRTNIR S
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
