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View Structure Prediction Details

Protein: l(1)G0007-PB
Organism: Drosophila melanogaster
Length: 534 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for l(1)G0007-PB.

Description E-value Query
Range
Subject
Range
gi|220947064 - gi|220947064|gb|ACL86075.1| l(1)G0007-PA [synthetic construct]
l(1)G0007-PA - The gene lethal (1) G0007 is referred to in FlyBase by the symbol Dmel\l(1)G0007 (CG32604, FBgn00267...
478.0 [0..1] [534..689]

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Predicted Domain #1
Region A:
Residues: [1-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSSKFATFF GNVPTFTIPG RTFPVDVMFS KNTCEDYVES AVKQALQVHL TPNEGDMLIF  60
   61 MPGQEDIEVT CEVLEERLAE IDNAPALSIL PIYSQLPSDL QAKIFQKSSD GLRKCVVATN 120
  121 IAETSLTVDG IIYVIDSGYC KLKVYNPRIG MDALQIYPIS QANANQRSGR AGRTGPGQAY 180
  181 RLYTQRQYKD ELLALTVPEI QRTNLANTVL LLKSLGVVDL LQFHFMDPPP QDNILNSLYQ 240
  241 LWILGALDHT GALTTLGRQM AEFPLDPPQC QMLIVACRMG CSAEVLIIVS MLSVPSIFYR 300
  301 PKGREDEADG VREKFQRPES DHLTYLNVYQ QWRQNNYSST WCNEHFIHIK AMRKVREVRQ 360
  361 QLKDIMTQQN L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.522879
Match: 1oywA
Description: Structure of the RecQ Catalytic Core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
4.704140727858 bayes_pls_golite062009
RNA binding 2.29590582680214 bayes_pls_golite062009
binding 2.05253348982328 bayes_pls_golite062009
structural constituent of ribosome 1.57653963868443 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
nucleic acid binding 1.41477043612798 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
hydrolase activity 0.770112659770838 bayes_pls_golite062009
mRNA binding 0.76699944561918 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
structural molecule activity 0.596382945962261 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.461763181659193 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.458831409927227 bayes_pls_golite062009
pyrophosphatase activity 0.455976987338331 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.422944846459286 bayes_pls_golite062009
snRNA binding 0.418985924846052 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [372-534]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVISCGIDWD IVRKCICSAY FYQAARLKGI GEYVNLRTGM PCHLHPTSAL YGLGTTPDYV  60
   61 VYHELIMTAK EYMQCATAVD GYWLAELGPM FFSVKESGRS GREKKKQAAE HLKEMEEQML 120
  121 KAQHEMEERK QQAAEREEQL ATKQEIATPG NATPRRTPAR IGL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 20.619789
Match: PF07717.7
Description: No description for PF07717.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle