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View Structure Prediction Details

Protein: Clic-PA, FBpp0311923
Organism: Drosophila melanogaster
Length: 260 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Clic-PA, FBpp0311923.

Description E-value Query
Range
Subject
Range
gi|95102944, gi|... - gi|95102944|gb|ABF51413.1| chloride intracellular channel isoform 1 [Bombyx mori], gi|114053119|ref|...
161.0 [0..13] [260..8]
gi|8052535 - gi|8052535|gb|AAF71799.1|AC013430_8 F3F9.13 [Arabidopsis thaliana]
159.0 [0..34] [260..7]
gi|125981787, gi... - gi|54643209|gb|EAL31953.1| GA10697-PA [Drosophila pseudoobscura], gi|125981787|ref|XP_001354897.1| G...
157.0 [0..13] [260..13]
gi|94469210 - gi|94469210|gb|ABF18454.1| chloride intracellular channel 6-like protein [Aedes aegypti]
157.0 [0..13] [259..8]
gi|58378935, gi|... - gi|58378935|ref|XP_309131.2| ENSANGP00000024624 [Anopheles gambiae str. PEST], gi|55245009|gb|EAA453...
154.0 [0..6] [260..6]
gi|93354450, gi|... - gi|94310598|ref|YP_583808.1| glutathione S-transferase-like protein [Ralstonia metallidurans CH34], ...
153.0 [0..3] [259..35]
gi|161336315, gi... - gi|161619504|ref|YP_001593391.1| glutathione S-transferase [Brucella canis ATCC 23365], gi|161336315...
gi|254704814 - gi|254704814|ref|ZP_05166642.1| glutathione S-transferase [Brucella suis bv. 3 str. 686]
gi|23502425, gi|... - gi|23502425|ref|NP_698552.1| glutathione S-transferase domain-containing protein [Brucella suis 1330...
149.0 [0..3] [258..35]
gi|21241356, gi|... - gi|21241356|ref|NP_640938.1| hypothetical protein XAC0585 [Xanthomonas axonopodis pv. citri str. 306...
148.0 [0..5] [258..37]
gi|7447302, gi|2... - pir||T06239 probable glutathione transferase (EC 2.5.1.18), 2,4-D inducible - soybean, gi|2920666|gb...
148.0 [0..34] [230..7]

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Predicted Domain #1
Region A:
Residues: [1-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVESQQSQ ETNGSSKFDV PEIELIIKAS TIDGRRKGAC LFCQEYFMDL YLLAELKTIS  60
   61 LKVTTVDMQK PPPDFRTNFE ATHPPILIDN GLAILENEKI ERHIMKNIPG GYNLFVQDKE 120
  121 VATLIENLYV KLKLMLVKKD EAKNNALLSH LRKINDHLSA RNTRFLTGDT MCCFDCELMP 180
  181 RLQHIRVAGK YFVDFEIPTH LTALWRYMYH MYQLDAFTQS CPADQDIINH YKLQQSLKMK 240
  241 KHEELETPTF TTYIPIDISE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 1rk4A
Description: Crystal Structure of a Soluble Dimeric Form of Oxidised CLIC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.44705858438242 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.44705858438242 bayes_pls_golite062009
chloride channel activity 3.43309717940669 bayes_pls_golite062009
anion channel activity 3.43309717940669 bayes_pls_golite062009
anion transmembrane transporter activity 2.95357085969061 bayes_pls_golite062009
ion transmembrane transporter activity 2.80355375991545 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.57358006453916 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
glutathione peroxidase activity 2.012364779649 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
ion channel activity 1.93467867578363 bayes_pls_golite062009
substrate-specific channel activity 1.85548385190106 bayes_pls_golite062009
passive transmembrane transporter activity 1.85004112385169 bayes_pls_golite062009
channel activity 1.85004112385169 bayes_pls_golite062009
voltage-gated chloride channel activity 1.53793640572798 bayes_pls_golite062009
voltage-gated anion channel activity 1.53793640572798 bayes_pls_golite062009
molecular transducer activity 1.48840493532061 bayes_pls_golite062009
signal transducer activity 1.48840493532061 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
transporter activity 1.27462890839069 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
transmembrane transporter activity 1.07599729927609 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 1.04609283259723 bayes_pls_golite062009
protein disulfide isomerase activity 1.04609283259723 bayes_pls_golite062009
gated channel activity 1.02378767677496 bayes_pls_golite062009
selenium binding 1.02136183687858 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 0.959318279607901 bayes_pls_golite062009
phospholipid-hydroperoxide glutathione peroxidase activity 0.874146425427531 bayes_pls_golite062009
substrate-specific transporter activity 0.861215137904704 bayes_pls_golite062009
voltage-gated ion channel activity 0.677675994999412 bayes_pls_golite062009
voltage-gated channel activity 0.661169709002081 bayes_pls_golite062009
transcription regulator activity 0.52671047749426 bayes_pls_golite062009
nucleic acid binding 0.32476916216195 bayes_pls_golite062009
DNA binding 0.278017923256183 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.0801269279614203 bayes_pls_golite062009
protein disulfide oxidoreductase activity 0.0719543694089202 bayes_pls_golite062009
transcription repressor activity 0.00678211696545472 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle