| Protein: | sws-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1425 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sws-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
903.0 | [0..1] | [1425..1] |
|
Region A: Residues: [1-159] |
1 11 21 31 41 51
| | | | | |
1 MDVLEMLRAS ASGSYNTIFS DAWCQYVSKQ ITATVYMYFA LVMMSLLFIA WFLYFKRMAR 60
61 LRLRDEIARS ISTVTNSSGD MRGLRFRKRD KMLFYGRRML RKMKNVSGQM YSSGKGYKRR 120
121 AVMRFARRIL QLRRDNMPLE MRTVEPPAEY LEETIEGSD
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [160-565] |
1 11 21 31 41 51
| | | | | |
1 RVPPDALYML QSIRIFGHFE KPVFLRLCKH TQLLELMAGD YLFKITDPDD SVYIVQSGMI 60
61 NVYISNADGS TLSLKTVRKG ESVTSLLSFI DVLSGNPSYY KTVTAKAIEK SVVIRLPMQA 120
121 FEEVFQDNPD VMIRVIQVIM IRLQRVLFTA LRNYLGLNAE LVQNHMRYKS VSTMSGPINS 180
181 QTSQSSRQAP NGPPMVISQM NLMQSAVSGT GSSGVSVTVT RPPSSPSRHS REEHTLSDPN 240
241 PNPDGSFHGT TNLFTEVHGD APNADLFHQQ QQQHSVGNLS TRRSSITLMA PDGSHSCLQT 300
301 PGVTTSIDMR LVQSSAVDSL RKELGLSEED SHIIEPFVEL RELEPNVTLI TEGNADDVCV 360
361 WFVMTGTLAV YQSNQDATRA KQDKSDMLIH FVHPGEIVGG LAMLTG
|
| Detection Method: | |
| Confidence: | 30.39794 |
| Match: | 1o7fA |
| Description: | Regulatory domain of epac2, domain 2; Regulatory domain of Epac2, domains 1 and 3 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.65363761161862 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.26124379267933 | bayes_pls_golite062009 |
| ion channel activity | 0.848870337502738 | bayes_pls_golite062009 |
| protein binding | 0.83595203347671 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.795033986592028 | bayes_pls_golite062009 |
| channel activity | 0.789135243365643 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.789135243365643 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 0.711500871939896 | bayes_pls_golite062009 |
| ligand-gated channel activity | 0.711500871939896 | bayes_pls_golite062009 |
| gated channel activity | 0.69445530625204 | bayes_pls_golite062009 |
| cation channel activity | 0.574425804123918 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.26551164934064 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.250292406962674 | bayes_pls_golite062009 |
|
Region A: Residues: [566-801] |
1 11 21 31 41 51
| | | | | |
1 EASAYTIRSR SITRIAFIRR AAIYQIMRQR PRIVLDLGNG VVRRLSPLVR QCDYALDWIF 60
61 LESGRAVYRQ DESSDSTYIV LSGRMRSVIT HPGGKKEIVG EYGKGDLVGI VEMITETSRT 120
121 TTVMAVRDSE LAKLPEGLFN AIKLRYPIVV TKLISFLSHR FLGSMQTRSG SGAPGAPVEA 180
181 NPVTHKYSTV ALVPITDEVP MTPFTYELYH SLCAIGPVLR LTSDVVRKQL GSNIFE
|
| Detection Method: | |
| Confidence: | 41.69897 |
| Match: | 1cx4A |
| Description: | Regulatory subunit of Protein kinase A |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.65363761161862 | bayes_pls_golite062009 |
| ion channel activity | 0.848870337502738 | bayes_pls_golite062009 |
| protein binding | 0.83595203347671 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.795033986592028 | bayes_pls_golite062009 |
| channel activity | 0.789135243365643 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.789135243365643 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 0.711500871939896 | bayes_pls_golite062009 |
| ligand-gated channel activity | 0.711500871939896 | bayes_pls_golite062009 |
| gated channel activity | 0.69445530625204 | bayes_pls_golite062009 |
| cation channel activity | 0.574425804123918 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.250292406962674 | bayes_pls_golite062009 |
|
Region A: Residues: [802-946] |
1 11 21 31 41 51
| | | | | |
1 AANEYRLTSW LAQQEDRNII TLYQCDSSLS AWTQRCMRQA DVILIVGLGD RSHLVGKFER 60
61 EIDRLAMRTQ KELVLLYPEA SNAKPANTLS WLNARPWVTK HHHVLCVKRI FTRKSQYRIN 120
121 DLYSRVLLSE PNMHSDFSRL ARWLT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [947-1246] |
1 11 21 31 41 51
| | | | | |
1 GNSIGLVLGG GGARGAAHIG MLKAIQEAGI PVDMVGGVSI GALMGALWCS ERNITTVTQK 60
61 AREWSKKMTK WFLQLLDLTY PITSMFSGRE FNKTIHDTFG DVSIEDLWIP YFTLTTDITA 120
121 SCHRIHTNGS LWRYVRSSMS LSGYMPPLCD PKDGHLLLDG GYVNNLPADV MHNLGAAHII 180
181 AIDVGSQDDT DLTNYGDDLS GWWLLYKKWN PFTSPVKVPD LPDIQSRLAY VSCVRQLEEV 240
241 KNSDYCEYIR PPIDKYKTLA FGSFDEIRDV GYVFGKNYFE SMAKAGRLGR FNQWFNKEPP 300
301
|
| Detection Method: | |
| Confidence: | 19.30103 |
| Match: | 1oxwA |
| Description: | Patatin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phospholipase activity | 3.87963112297417 | bayes_pls_golite062009 |
| phospholipase A2 activity | 3.8689576466535 | bayes_pls_golite062009 |
| lipase activity | 1.83391969295473 | bayes_pls_golite062009 |
| catalytic activity | 1.681309422157 | bayes_pls_golite062009 |
| binding | 1.32516854558392 | bayes_pls_golite062009 |
| hydrolase activity | 1.23737416083983 | bayes_pls_golite062009 |
| fatty acid synthase activity | 1.20394174397151 | bayes_pls_golite062009 |
| S-acyltransferase activity | 1.07865077162953 | bayes_pls_golite062009 |
| [acyl-carrier-protein] S-malonyltransferase activity | 0.812816692540436 | bayes_pls_golite062009 |
| S-malonyltransferase activity | 0.812816692540436 | bayes_pls_golite062009 |
| malonyltransferase activity | 0.812816692540436 | bayes_pls_golite062009 |
| calcium-independent phospholipase A2 activity | 0.5938636898178 | bayes_pls_golite062009 |
| carboxylesterase activity | 0.431665185524913 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.39017969987234 | bayes_pls_golite062009 |
| acyltransferase activity | 0.350701756346828 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups other than amino-acyl groups | 0.295883900540457 | bayes_pls_golite062009 |
|
Region A: Residues: [1247-1425] |
1 11 21 31 41 51
| | | | | |
1 KRVNHASLNE YTFIDLAQIV CRLPETYAVN TAELFSEDED CDGYISEPTT LNTDRRRIQV 60
61 SRAGNSLSFS ETEMDSDVEL DLKLERKTDK STQSSPPSNS RSDMRGKEEA RHMSNWHWGV 120
121 KHKDETGSGA TEATKTQTGQ EQELQQEQQD QGATAEQLVD KDKEENKENR SSPNNETKN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
