| Protein: | Sirt4-PC |
| Organism: | Drosophila melanogaster |
| Length: | 312 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sirt4-PC.
| Description | E-value | Query Range |
Subject Range |
|
|
297.0 | [0..11] | [303..1] |
|
Region A: Residues: [1-312] |
1 11 21 31 41 51
| | | | | |
1 MRVGQLLRFR STSLRSSTAR QEYVPHHKPV VEDDIKRLED FLLSKPNVLV LTGAGISTES 60
61 GIPDYRSEGV GLYARSNHKP VQHMEFVKSS AVRKRYWARN FVGWPKFSAT QPNATHHALA 120
121 RFEREERVQA VVTQNVDRLH TKAGSRNVVE VHGSGYVVKC LSCEYRIDRH EFQSILASLN 180
181 PAFKDAPDMI RPDGDVEIPL EYIENFRIPE CTQCGGDLKP EIVFFGDSVP RPRVDQIAGM 240
241 VYNSDGLLVL GSSLLVFSGY RVVLQTKDLK LPVGIVNIGE TRADHLADIK ISAKCGDVIP 300
301 KLFDFRNSKS VS
|
| Detection Method: |  |
| Confidence: | 69.30103 |
| Match: | 1ma3A |
| Description: | AF0112, Sir2 homolog (Sir2-AF2) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| NAD-dependent histone deacetylase activity | 4.66387831647923 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 4.66387831647923 | bayes_pls_golite062009 |
| NAD+ ADP-ribosyltransferase activity | 4.62921662347995 | bayes_pls_golite062009 |
| histone deacetylase activity | 4.52265070993834 | bayes_pls_golite062009 |
| protein deacetylase activity | 4.51418609991523 | bayes_pls_golite062009 |
| deacetylase activity | 3.60611826633675 | bayes_pls_golite062009 |
| transcription regulator activity | 2.31731368009317 | bayes_pls_golite062009 |
| DNA binding | 1.84059392605809 | bayes_pls_golite062009 |
| nucleic acid binding | 1.83132687449755 | bayes_pls_golite062009 |
| transcription repressor activity | 1.74876325396581 | bayes_pls_golite062009 |
| binding | 1.63619372613603 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 1.38412624618353 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.16656035070431 | bayes_pls_golite062009 |
| transporter activity | 1.02987325768951 | bayes_pls_golite062009 |
| NAD(P)+-protein-arginine ADP-ribosyltransferase activity | 0.963519974868694 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.879539673228343 | bayes_pls_golite062009 |
| transcription factor activity | 0.758967814548108 | bayes_pls_golite062009 |
| catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
| transcription factor binding | 0.64778523540991 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.62029498163975 | bayes_pls_golite062009 |
| histone binding | 0.60825982588532 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.56000396203236 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.52020182886741 | bayes_pls_golite062009 |
| protein binding | 0.475479132768057 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.47231237137431 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.128843577740998 | bayes_pls_golite062009 |
| hydrolase activity | 0.0875567934348688 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.05634462944063 | bayes_pls_golite062009 |
