| Protein: | Ptp4E-PD, Ptp4E-... |
| Organism: | Drosophila melanogaster |
| Length: | 1767 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ptp4E-PD, Ptp4E-....
| Description | E-value | Query Range |
Subject Range |
|
|
1129.0 | [0..1] | [1767..1] |
|
Region A: Residues: [1-78] |
1 11 21 31 41 51
| | | | | |
1 MDCATRKQQQ LRAHHQQQQI QIQTHGRKRQ QLQKQRHNHH HYYQNSQQQQ KHFVWLVVGI 60
61 LTIFLAQHAN AADLVINV
|
| Detection Method: |  |
| Confidence: | 49.522879 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [79-699] |
1 11 21 31 41 51
| | | | | |
1 PNASSNANAF YRIDYSPPFG FPEPNTTIPA SDIGKDIKFS RALPGTEYNF WLYYTNSTHR 60
61 EQLTWTVNIT TAPDPPANLS VQLRSSKSAF ITWRPPGSGR YSGFRIRVLG LTDLPFERSY 120
121 SLEGNETLQL SAKELTPGGS YQVQAYSVYQ GKESVAYTSR NFTTKPNTPG KFIVWFRNET 180
181 TLLVLWQPPF PAGIYTHYRV SITPDDAIQS VLYVEREGEP PGPAQAAFKG LVPGREYNIS 240
241 VQTVSEDETS SVPTTARYLT VPERVLNVTF DEAYTTSSSF RVRWEPPRTY SEFDAYQVML 300
301 STSRRIFNVP RAANGDSVYF DYPDILEPGR TYEVVVKTIA DNVNSWPASG EVTLRPRPVR 360
361 SLGGFLDDRS NALHISWEPA ETGRQDSYRI SYHEQTNASE VPAPFPVAAE SQITTNLTEY 420
421 TLDSLLAGRR YLIAVQALSK GVASNASDIT RYTRPAAPLI QELRSIDQGL MLSWRSDVNS 480
481 RQDRYEVHYQ RNGTREERTM ATNETSLTIH YLHPGSGYEV KVHAISHGVR SEPHSYFQAV 540
541 FPKPPQNLTL QTVHTNLVVL HWQAPEGSDF SEYVVRYRTD ASPWQRISGL HENEARIKDM 600
601 HYGERYLVQV NTVSFGVESP H
|
| Detection Method: | |
| Confidence: | 15.0 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [700-890] |
1 11 21 31 41 51
| | | | | |
1 PLELNVTMPP QPVSNVVPLV DSRNLTLEWP RPDGHVDFYT LKWWPTDEED RVEFKNVTQL 60
61 EDLSSPSVRI PIEDLSPGRQ YRFEVQASSN GIRSGTTHLS TRTMPLIQSD VFIANAGHEQ 120
121 GQDETITLSY TPTPADSTRF DIYRFSMGDP TIKDKEKLAN DTERKLSFSG LTPGKLYNVT 180
181 VWTVSGGVAS L
|
| Detection Method: | |
| Confidence: | 55.69897 |
| Match: | 1fnfA |
| Description: | FRAGMENT OF HUMAN FIBRONECTIN ENCOMPASSING TYPE-III REPEATS 7 THROUGH 10 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [891-992] |
1 11 21 31 41 51
| | | | | |
1 PVQRLYRLHP LPISDLKAIQ VAAREITLHW TAPAGEYTDF ELQYLSADEE APQLLQNVTK 60
61 NTEITLQGLR PYHNYTFTVV VRSGSIQGTD FADVSVSTLM RS
|
| Detection Method: | |
| Confidence: | 39.69897 |
| Match: | 1fnhA |
| Description: | Fibronectin, different Fn3 modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transmembrane receptor activity | 4.21125462030555 | bayes_pls_golite062009 |
| receptor activity | 4.09185309744435 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| molecular transducer activity | 3.24090483126624 | bayes_pls_golite062009 |
| signal transducer activity | 3.24090483126624 | bayes_pls_golite062009 |
| cytokine binding | 3.21238178184503 | bayes_pls_golite062009 |
| growth factor binding | 2.99437744892471 | bayes_pls_golite062009 |
| cytokine receptor activity | 2.76876397305497 | bayes_pls_golite062009 |
| binding | 2.69537882298808 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| peptide hormone binding | 1.9205359237864 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.61421027298524 | bayes_pls_golite062009 |
| protein kinase activity | 1.60674218431738 | bayes_pls_golite062009 |
| kinase activity | 1.57994485110649 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.44501485815273 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| hormone binding | 1.31120662451488 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.18385625326067 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.18385625326067 | bayes_pls_golite062009 |
| transferase activity | 1.13635878582843 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| nucleic acid binding | 0.745125737480015 | bayes_pls_golite062009 |
| transcription regulator activity | 0.718355770608923 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| cell surface binding | 0.694105914814106 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| DNA binding | 0.609787884452433 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 0.60649323348068 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| peptide binding | 0.47885601366674 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| interleukin-2 binding | 0.240383688164201 | bayes_pls_golite062009 |
| SH2 domain binding | 0.218079243436961 | bayes_pls_golite062009 |
| structural molecule activity | 0.18965275490219 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| polysaccharide binding | 0.0807821124164596 | bayes_pls_golite062009 |
| transcription factor activity | 0.0148251912049181 | bayes_pls_golite062009 |
|
Region A: Residues: [993-1195] |
1 11 21 31 41 51
| | | | | |
1 SAPISASYQT LTAPPGKVDY FQPSDVQPGE VTFEWSLEPA EQHGPIDYFR ITCQNADDAA 60
61 DVSSYEFPVN ATQGKIDGLV PGNHYIFRIQ AKSALGYGAE REHIQTMPIL APPVPEPSVT 120
121 PLEVSRTSST IEISFRQGYF SNAHGMVRSY TIIIAEDVGK NASGLEMPSW QDVQAYTVWL 180
181 PYQAIEPYNP FLTSNGSRKS SLE
|
| Detection Method: | |
| Confidence: | 6.35 |
| Match: | 2geeA |
| Description: | No description for 2geeA was found. |
|
Region A: Residues: [1196-1312] |
1 11 21 31 41 51
| | | | | |
1 AEHFTIGTAN CDKHQAGYCN GPLRAGTTYR IKIRAFTDED KFTDTVYSSP ITTERSDTVI 60
61 VAATVSAVLL VAMVLVVVYC QHRCQLIRRA SKLARMQDEL AALPEGYITP NRPVHVK
|
| Detection Method: | |
| Confidence: | 81.69897 |
| Match: | 2b3oA |
| Description: | Crystal structure of human tyrosine phosphatase SHP-1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1313-1767] |
1 11 21 31 41 51
| | | | | |
1 DFSEHYRIMS ADSDFRFSEE FEELKHVGRD QACSFANLPC NRPKNRFTNI LPYDHSRFKL 60
61 QPVDDDDGSD YINANYMPGH NSPREFIVTQ GPLHSTREEF WRMCWESNSR AIVMLTRCFE 120
121 KGREKCDQYW PVDRVAMFYG DIKVQLIIDT HYHDWSISEF MVSRNCESRI MRHFHFTTWP 180
181 DFGVPEPPQS LVRFVRAFRD VIGTDMRPII VHCSAGVGRS GTFIALDRIL QHIHKSDYVD 240
241 IFGIVFAMRK ERVFMVQTEQ QYVCIHQCLL AVLEGKEHLL ADSLELHAND GYEVTKIYLE 300
301 RQPQTKMGTL PIRASLAMAE KLDADLMTNK DEDEDQEQQQ QQQLQLATEV KPKGSNDDEE 360
361 DEEDDDDDDD DQQPLNNETT ATLSSASCSS STHDVHVVLQ EAIEKPKQEQ ERICAGTQSH 420
421 ADTESDNTDS DDDDEDGDGK VAKDGAVADE DGWWY
|
| Detection Method: | |
| Confidence: | 151.0 |
| Match: | 2fh7A |
| Description: | Crystal structure of the phosphatase domains of human PTP SIGMA |
Matching Structure (courtesy of the PDB): |
|
