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View Structure Prediction Details

Protein: rap-PB, rap-PA
Organism: Drosophila melanogaster
Length: 478 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rap-PB, rap-PA.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
539.0 [0..3] [475..1188]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSPEYEKRI LKHYSPVARN LFNNFESSTT PTSLDRFIPC RAYNNWQTNF ASINKSNDNS  60
   61 PQTSKKQRDC GETARDSLAY SCLLKNELLG SAIDDVKTAG EERNENAYTP AA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 2ojhA
Description: No description for 2ojhA was found.

Predicted Domain #2
Region A:
Residues: [113-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRSLFKYQSP TKQDYNGECP YSLSPVSAKS QKLLRSPRKA TRKISRIPFK VLDAPELQDD  60
   61 FYLNLVDWSS QNVLAVGLGS CVYLWSACTS QVTRLCDLSP DANTVTSVSW NERGNTVAVG 120
  121 THHGYVTVWD VAANKQINKL NGHSARVGAL AWNSDILSSG SRDRWIIQRD TRTPQLQSER 180
  181 RLAGHRQEVC GLKWSPDNQY LASGGNDNRL YVWNQHSVNP VQSYTEHMAA VKAIAWSPHH 240
  241 HGLLASGGGT ADRCIRFWNT LTGQPMQCVD TGSQVCNLAW SKHSSELVST HGYSQNQILV 300
  301 WKYPSLTQVA KLTGHSYRVL YLALSPDGEA IVTGAGDETL RFWNVFSKAR SQKENKSVLN 360
  361 LFANIR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.154902
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 7.6976390971701 bayes_pls_golite062009
small conjugating protein ligase activity 7.38724968585043 bayes_pls_golite062009
6.67009948605948 bayes_pls_golite062009
acid-amino acid ligase activity 6.41826641115519 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.36089569430187 bayes_pls_golite062009
RNA binding 3.77273677738815 bayes_pls_golite062009
GTPase activity 3.20623818975951 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
transcription repressor activity 2.29049708962212 bayes_pls_golite062009
actin binding 2.27900251096697 bayes_pls_golite062009
snoRNA binding 2.27164613239345 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
ligase activity 1.82531515493699 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
structural molecule activity 1.47097979074281 bayes_pls_golite062009
transcription corepressor activity 1.41752877005447 bayes_pls_golite062009
receptor activity 1.12819778129653 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
mRNA binding 1.05053985350578 bayes_pls_golite062009
molecular transducer activity 0.974380908248463 bayes_pls_golite062009
signal transducer activity 0.974380908248463 bayes_pls_golite062009
angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
type 1 angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
transporter activity 0.807925044108643 bayes_pls_golite062009
dynactin binding 0.71086831563355 bayes_pls_golite062009
G-protein-coupled receptor binding 0.700626674902544 bayes_pls_golite062009
actin filament binding 0.554537899540618 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.426429095658617 bayes_pls_golite062009
substrate-specific transporter activity 0.414491774707324 bayes_pls_golite062009
kinase activity 0.387572734234845 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.226335610368636 bayes_pls_golite062009
hydrolase activity 0.181211933860468 bayes_pls_golite062009
histone binding 0.166694897714113 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.116261617458825 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009

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