| Protein: | tll-PA |
| Organism: | Drosophila melanogaster |
| Length: | 452 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tll-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
288.0 | [0..1] | [449..27] |
|
Region A: Residues: [1-131] |
1 11 21 31 41 51
| | | | | |
1 MQSSEGSPDM MDQKYNSVRL SPAASSRILY HVPCKVCRDH SSGKHYGIYA CDGCAGFFKR 60
61 SIRRSRQYVC KSQKQGLCVV DKTHRNQCRA CRLRKCFEVG MNKDAVQHER GPRNSTLRRH 120
121 MAMYKDAMMG A
|
| Detection Method: |  |
| Confidence: | 21.69897 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [132-452] |
1 11 21 31 41 51
| | | | | |
1 GEMPQIPAEI LMNTAALTGF PGVPMPMPGL PQRAGHHPAH MAAFQPPPSA AAVLDLSVPR 60
61 VPHHPVHQGH HGFFSPTAAY MNALATRALP PTPPLMAAEH IKETAAEHLF KNVNWIKSVR 120
121 AFTELPMPDQ LLLLEESWKE FFILAMAQYL MPMNFAQLLF VYESENANRE IMGMVTREVH 180
181 AFQEVLNQLC HLNIDSTEYE CLRAISLFRK SPPSASSTED LANSSILTGS GSPNSSASAE 240
241 SRGLLESGKV AAMHNDARSA LHNYIQRTHP SQPMRFQTLL GVVQLMHKVS SFTIEELFFR 300
301 KTIGDITIVR LISDMYSQRK I
|
| Detection Method: | |
| Confidence: | 48.69897 |
| Match: | 1dkfA |
| Description: | Retinoid-X receptor alpha (RXR-alpha) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| receptor activity | 3.45094937361521 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription coactivator activity | 2.27959329058894 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 1.71585537346083 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| promoter binding | 1.28787959668198 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| transcription activator binding | 0.98577399552136 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.47826452126899 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.42652610679613 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
| hormone binding | 0.0792077987589768 | bayes_pls_golite062009 |
