YRC Public Data Repository - Protein Structure Prediction

Protein:	FBpp0301104, FBp...
Organism:	Drosophila melanogaster
Length:	260 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0301104, FBp....

Description	E-value	Query Range	Subject Range
gi\|21429036 - gi\|21429036\|gb\|AAM50237.1\| LD13909p [Drosophila melanogaster]	252.0	[0..1]	[260..1]
gi\|125776034, gi... - gi\|54638887\|gb\|EAL28289.1\| GA19542-PA [Drosophila pseudoobscura], gi\|125776034\|ref\|XP_001359145.1\| G...	229.0	[0..1]	[260..1]
gi\|62644938 - gi\|62644938\|ref\|XP_231143.3\| PREDICTED: similar to Uridine-cytidine kinase 1 (UCK 1) (Uridine monoph...	224.0	[0..15]	[245..11]
UCK1_MOUSE - Uridine-cytidine kinase 1 OS=Mus musculus GN=Uck1 PE=1 SV=2	224.0	[0..15]	[245..11]
gi\|76611769 - gi\|76611769\|ref\|XP_614178.2\| PREDICTED: similar to uridine-cytidine kinase 2 [Bos taurus]	223.0	[0..20]	[247..230]
gi\|18568109 - gi\|18568109\|gb\|AAL75943.1\|AF125106_1 uridine kinase [Homo sapiens]	222.0	[0..16]	[245..11]
gi\|109109986 - gi\|109109986\|ref\|XP_001105895.1\| PREDICTED: similar to uridine-cytidine kinase 1 isoform 4 [Macaca m...	221.0	[0..16]	[245..12]
UKL3_ARATH - Uridine kinase-like protein 3 OS=Arabidopsis thaliana GN=UKL3 PE=2 SV=1	221.0	[0..4]	[259..21]
UCK1_DANRE - Uridine-cytidine kinase 1 OS=Danio rerio GN=uck1 PE=2 SV=1	221.0	[0..21]	[238..11]

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Predicted Domain #1

Region A:
Residues: [1-260]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDLRNADTL RLPNGDGAAA NDEVKSPFLI GVAGGTASGK STVCKKIMEQ LGQAEMDHTQ  60
   61 RQVVSISQDS FYRELTPAEK AKAQKGLFNF DHPDAFNEEL MYSTLQNILK GHKVEIPSYD 120
  121 YRTNSLDFEN VLVIYPADVV LFEGILVFYF PKIRELFHMK LFVDTDSDTR LARRVPRDIN 180
  181 ERGRDLDAVL TQYMTFVKPA FEEFCSPTKK FADVIIPRGA DNTVAIDLIV HHIGEILATT 240
  241 NSAQHSNTVR VAASSMKRDH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.69897
Match:	1udwA
Description:	Crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, CTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleobase, nucleoside, nucleotide kinase activity	3.66392587433723	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.28726855139279	bayes_pls_golite062009
nucleotide kinase activity	2.24094813695083	bayes_pls_golite062009
pyrophosphatase activity	2.23754609668547	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.21702600128327	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.21503003850174	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	1.96697952975573	bayes_pls_golite062009
binding	1.8576045268999	bayes_pls_golite062009
transporter activity	1.85044926113762	bayes_pls_golite062009
ATPase activity	1.70670922135201	bayes_pls_golite062009
transmembrane transporter activity	1.656935231793	bayes_pls_golite062009
hydrolase activity	1.20846280768115	bayes_pls_golite062009
ATPase activity, coupled	1.02588328213159	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
ATP binding	0.98146619596929	bayes_pls_golite062009
adenyl ribonucleotide binding	0.949788783884952	bayes_pls_golite062009
adenyl nucleotide binding	0.931486373329219	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
GTPase activity	0.768815888267067	bayes_pls_golite062009
kinase activity	0.691112783105676	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.499834566483656	bayes_pls_golite062009
substrate-specific transporter activity	0.464456497491373	bayes_pls_golite062009
adenylate kinase activity	0.447752711852745	bayes_pls_golite062009
active transmembrane transporter activity	0.434775387083003	bayes_pls_golite062009
small conjugating protein ligase activity	0.390479076640045	bayes_pls_golite062009
protein binding	0.378225828131122	bayes_pls_golite062009
primary active transmembrane transporter activity	0.294474570607914	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.282352478532746	bayes_pls_golite062009
ubiquitin-protein ligase activity	0.226172885205141	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.220608508617331	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.219533217661421	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.219157471322311	bayes_pls_golite062009
nucleic acid binding	0.216266069700019	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.0756212238097211	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0430764033739892	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: