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View Structure Prediction Details

Protein: twin-PD
Organism: Drosophila melanogaster
Length: 358 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for twin-PD.

Description E-value Query
Range
Subject
Range
twin-PB - The gene twin is referred to in FlyBase by the symbol Dmel\twin (CG31137, FBgn0011725). It is a prot...
gi|220951022, gi... - gi|220957942|gb|ACL91514.1| twin-PB [synthetic construct], gi|220951022|gb|ACL88054.1| twin-PB [synt...
316.0 [0..1] [358..188]

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Predicted Domain #1
Region A:
Residues: [1-358]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCYNVLCDKY ATRQMYGYCP SWALCWEYRK KSIIDEIRHY AADIISLQEI ETEQFYHFFL  60
   61 PELKNDGYEG IFSPKSRAKT MSELERKYVD GCAIFFRASK FTLIKESLIE FNQLAMANAE 120
  121 GSDNMLNRVM PKDNIGLAAL LKVKENAWEP MSEVTQISQP LLVCTAHIHW DPEFCDVKLI 180
  181 QTMMLSNELK TIIDEASHSF RPGHKNDSNA VQLLLCGDFN SLPDSGVVEF LGKGRVSMDH 240
  241 LDFKDMGYKS CLQRLLSNDT NEFTHSFKLA SAYNEDIMPH TNYTFDFKGI IDYIFYTKTG 300
  301 MVPLGLLGPV SNDWLRENKV VGCPHPHIPS DHFPLLVELE LMHTASQQAP PNGLINRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.0
Match: 2ddrA
Description: No description for 2ddrA was found.

Predicted functions:

Term Confidence Notes
hydrolase activity 3.28400034252781 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 3.04161110413795 bayes_pls_golite062009
DNA binding 2.38216646754749 bayes_pls_golite062009
transcription regulator activity 2.37867140645121 bayes_pls_golite062009
nucleic acid binding 2.37728600449241 bayes_pls_golite062009
nuclease activity 1.78432551160775 bayes_pls_golite062009
catalytic activity 1.76511376991978 bayes_pls_golite062009
binding 1.74593496417303 bayes_pls_golite062009
deoxyribonuclease activity 1.6713040226181 bayes_pls_golite062009
transcription coactivator activity 1.51022821676155 bayes_pls_golite062009
exonuclease activity 1.44893971411928 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.25010124971419 bayes_pls_golite062009
oxidoreductase activity 1.00650797438916 bayes_pls_golite062009
ribonuclease activity 0.934548175624486 bayes_pls_golite062009
transcription activator activity 0.885026804340494 bayes_pls_golite062009
transcription factor binding 0.77254170640454 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.738975226345995 bayes_pls_golite062009
exodeoxyribonuclease activity 0.73001958440393 bayes_pls_golite062009
transcription cofactor activity 0.58884884939295 bayes_pls_golite062009
protein binding 0.476649214025345 bayes_pls_golite062009
endonuclease activity 0.288539805949629 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 0.228910502815798 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.100365481550461 bayes_pls_golite062009
phosphatase activity 0.00559251346312178 bayes_pls_golite062009

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