| Protein: | p53-PA, p53-PC |
| Organism: | Drosophila melanogaster |
| Length: | 385 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for p53-PA, p53-PC.
| Description | E-value | Query Range |
Subject Range |
|
|
430.0 | [0..1] | [384..8] |
|
Region A: Residues: [1-320] |
1 11 21 31 41 51
| | | | | |
1 MYISQPMSWH KESTDSEDDS TEVDIKEDIP KTVEVSGSEL TTEPMAFLQG LNSGNLMQFS 60
61 QQSVLREMML QDIQIQANTL PKLENHNIGG YCFSMVLDEP PKSLWMYSIP LNKLYIRMNK 120
121 AFNVDVQFKS KMPIQPLNLR VFLCFSNDVS APVVRCQNHL SVEPLTANNA KMRESLLRSE 180
181 NPNSVYCGNA QGKGISERFS VVVPLNMSRS VTRSGLTRQT LAFKFVCQNS CIGRKETSLV 240
241 FCLEKACGDI VGQHVIHVKI CTCPKRDRIQ DERQLNSKKR KSVPEAAEED EPSKVRRCIA 300
301 IKTEDTESND SRDCDDSAAE
|
| Detection Method: |  |
| Confidence: | 85.0 |
| Match: | 1uolA |
| Description: | Crystal structure of the human p53 core domain mutant M133L/V203A/N239Y/N268D at 1.9 A resolution. |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.42929256050781 | bayes_pls_golite062009 |
| DNA binding | 5.31133900263778 | bayes_pls_golite062009 |
| nucleic acid binding | 5.16722510757739 | bayes_pls_golite062009 |
| DNA strand annealing activity | 4.57315860395948 | bayes_pls_golite062009 |
| transcription factor activity | 4.50526425463039 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.91938513552138 | bayes_pls_golite062009 |
| transcription activator activity | 3.89749713667575 | bayes_pls_golite062009 |
| binding | 3.82913410895101 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.14317875446423 | bayes_pls_golite062009 |
| protein binding | 2.61625563263605 | bayes_pls_golite062009 |
| structure-specific DNA binding | 2.36676277465674 | bayes_pls_golite062009 |
| double-stranded DNA binding | 2.30995267491835 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.96307110502121 | bayes_pls_golite062009 |
| chromatin binding | 1.28001279726096 | bayes_pls_golite062009 |
| transcription repressor activity | 1.27337392672914 | bayes_pls_golite062009 |
| copper ion binding | 1.24203749926155 | bayes_pls_golite062009 |
| transcription factor binding | 0.628837188707778 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.35905469882415 | bayes_pls_golite062009 |
| protein dimerization activity | 0.0889583851427092 | bayes_pls_golite062009 |
|
Region A: Residues: [321-385] |
1 11 21 31 41 51
| | | | | |
1 WNVSRTPDGD YRLAITCPNK EWLLQSIEGM IKEAAAEVLR NPNQENLRRH ANKLLSLKKR 60
61 AYELP
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
