| Protein: | E2f-PA, E2f-PC, ... |
| Organism: | Drosophila melanogaster |
| Length: | 805 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for E2f-PA, E2f-PC, ....
| Description | E-value | Query Range |
Subject Range |
|
|
662.0 | [0..1] | [805..1] |
|
Region A: Residues: [1-191] |
1 11 21 31 41 51
| | | | | |
1 MSKFFVNVAP INNSNSSSSH TTTSSNTQRH QQHQQHYGGS GTTGHTMVAR RLNYDLHGGT 60
61 TSINNNNNIV IKNESVDLDY DHVLSSSDSN SNGGVAAHLR DHVYISLDKG HNTGAVATAA 120
121 AAATAGHTQQ QLQQQHHHQN QQQRKATGKS NDITNYYKVK RRPHAVSDEI HPKKQAKQSA 180
181 HHQTVYQKHT A
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [192-312] |
1 11 21 31 41 51
| | | | | |
1 SSAPQQLRHS HHQLRHDADA ELDEDVVERV AKPASHHPFS LSTPQQQLAA SVASSSSSGD 60
61 RNRADTSLGI LTKKFVDLLQ ESPDGVVDLN EASNRLHVQK RRIYDITNVL EGINILEKKS 120
121 K
|
| Detection Method: | |
| Confidence: | 26.0 |
| Match: | 1cf7A |
| Description: | Cell cycle transcription factor E2F-4 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.55329976718261 | bayes_pls_golite062009 |
| DNA binding | 5.08959163553491 | bayes_pls_golite062009 |
| nucleic acid binding | 4.99681957904233 | bayes_pls_golite062009 |
| transcription factor activity | 4.33152142980289 | bayes_pls_golite062009 |
| transcription activator activity | 3.70589483230587 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.58179858678904 | bayes_pls_golite062009 |
| binding | 3.52874320222492 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.60738445921725 | bayes_pls_golite062009 |
| transcription repressor activity | 2.22485867684613 | bayes_pls_golite062009 |
| protein binding | 1.80415286835431 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.2723726467408 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.913018999939773 | bayes_pls_golite062009 |
| transcription factor binding | 0.85714789329232 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.66743181561551 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.23177057841536 | bayes_pls_golite062009 |
|
Region A: Residues: [313-487] |
1 11 21 31 41 51
| | | | | |
1 NNIQWRCGQS MVSQERSRHI EADSLRLEQQ ENELNKAIDL MRENLAEISQ EVENSGGMAY 60
61 VTQNDLLNVD LFKDQIVIVI KAPPEAKLVL PNTKLPREIY VKAENSGEIN VFLCHDTSPE 120
121 NSPIAPGAGY VGAPGAGCVR TATSTRLHPL TNQRLNDPLF NNIDAMSTKG LFQTP
|
| Detection Method: | |
| Confidence: | 22.69897 |
| Match: | 2azeA |
| Description: | Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [488-560] |
1 11 21 31 41 51
| | | | | |
1 YRSARNLSKS IEEAAKQSQP EYNNICDIAM GQHHNLNQQQ QQQQQQLLQQ PEEDDVDVEL 60
61 NQLVPTLTNP VVR
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [561-805] |
1 11 21 31 41 51
| | | | | |
1 THQFQQHQQP SIQELFSSLT ESSPPTPTKR RREAAAAAIA AGSSTTATTT LNSHNNRNHS 60
61 NHSNHSNHSS SNNSKSQPPT IGYGSSQRRS DVPMYNCAME GATTTSATAD TTAATSRSAA 120
121 ASSLQMQFAA VAESNNGSSS GGGGGGGGYG SIAGAGANAD PHQPYSHDRN SLPPGVADCD 180
181 ANSNSSSVTL QGLDALFNDI GSDYFSNDIA FVSINPPDDN DYPYALNANE GIDRLFDFGS 240
241 DAYGP
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
