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View Structure Prediction Details

Protein: SNF4Agamma-PF, S...
Organism: Drosophila melanogaster
Length: 1400 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNF4Agamma-PF, S....

Description E-value Query
Range
Subject
Range
gi|4007492 - gi|4007492|gb|AAC95306.1| SNF4/AMP-activated protein kinase gamma subunit; SNF4A; noncatalytic subun...
481.0 [0..754] [1400..1]

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Predicted Domain #1
Region A:
Residues: [1-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATNCDFIEQ PVKQQPLANA PVMGVQEDKA QEPKELPDEP AKQPDGQPYQ HFAGEDSFEC  60
   61 AFESTMDDLE QGVLDGYESD SEASANDQIT DSASSGSLGQ LAQQQQREER LRGLPGPLHG 120
  121 QHIDSEMLKC MPRSNSFDFH SSSGSSSDDE DDPDDDDDDQ VHHSLGLSLS GK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [173-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVKVDLYSGH QRPGYLLPPY IERRRLSQCK EEDDEDEGDR TQLGGGSSST GESTKSEKAS  60
   61 KAPPRPPTPQ DEASKEKFKD LERLRQQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [260-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FMHKIDRINT RNIEESEAPP PPPPPPPPIP ATILPKALKA LLHTQEPVAP PSRPSPVGPP  60
   61 SPAPTSSVIV AKETPVPVTP EPVSPLPLPT EPPLIIKGKF KVTLAQETPE LRVEAQKLSK 120
  121 LNA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [383-631]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNAHTISFP SSFGGYSSVQ GLFSQRYGSN RFPTAAPHMS KQFFEPSLVE IRTPAQSNVA  60
   61 LNTTGLANSN HQSLTCDTNS LANKPRTPSE RELDEIWIRR QDGGLSGTAA PGAPGAPLPL 120
  121 LQQQQQQQRP VSLGGASTMP RLLRSESSAS TTSPSRQLTN SGSVSVSVSD DEQDGSLGGA 180
  181 GRMPGSRPSS APAEPNAKAA KKAYKKMEKE QRRQEKEQSR REKEARKLER ETARRNEREA 240
  241 AKLEKINRH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [632-888]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEKISRSTER MAMAGVGSRS GSLERRRSGE DSPVLNQSTV HGIASPNRRP TIFDVFRPRA  60
   61 KSDAKRQKEK HLLDPSSADS SATSSTYSVS GGTGPATSSA AGGAGGAAAA AGQGAAGGAG 120
  121 GLMNSMKVAM QNFSHRQHPA VTITSADGTQ STAKSKYKDG SAHPHQGSDA QYYHTVTAVR 180
  181 PNSSQRSPMT KVMDLFRHRS SSVVSEADKR KARAAAHQQQ LAVQSAHMRR ASADLEKRRA 240
  241 SVGAAGRGLR GDGTLDP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [889-1018]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HHAAILFRDS RGLPVADPFL EKVNLSDLEE DDSQIFVKFF RFHKCYDLIP TSAKLVVFDT  60
   61 QLLVKKAFYA LVYNGVRAAP LWDSEKQQFV GMLTITDFIK ILQMYYKSPN ASMEQLEEHK 120
  121 LDTWRSVLHN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.522879
Match: 2v8qE
Description: No description for 2v8qE was found.

Predicted Domain #7
Region A:
Residues: [1019-1400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVMPLVSIGP DASLYDAIKI LIHSRIHRLP VIDPATGNVL YILTHKRILR FLFLYINELP  60
   61 KPAYMQKSLR ELKIGTYNNI ETADETTSII TALKKFVERR VSALPLVDSD GRLVDIYAKF 120
  121 DVINLAAEKT YNDLDVSLRK ANEHRNEWFE GVQKCNLDES LYTIMERIVR AEVHRLVVVD 180
  181 ENRKVIGIIS LSDILLYLVL RPSGEGVGGS ESSLRASDPV LLRKVAEVEI PATAAAATTT 240
  241 TPPRSPSAGS GNRSLIEDIP EEETAPARSD DADSDNNKSA SEDKANNNQH DQTTTAATAN 300
  301 GDSNNSPVEV SFADEAQEEE AADQVERSNC DDDDQPALAE IERKNASMDD DEDDGMSSAV 360
  361 SAASALGQSL TPAAQEMALV SE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 125.0
Match: 1zfjA
Description: Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphorylase kinase regulator activity 8.18623772563485 bayes_pls_golite062009
AMP-activated protein kinase activity 7.98159515020845 bayes_pls_golite062009
cAMP-dependent protein kinase inhibitor activity 7.37900747121671 bayes_pls_golite062009
cAMP-dependent protein kinase regulator activity 2.72879349930537 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.65736716029442 bayes_pls_golite062009
protein kinase activity 2.63659198898943 bayes_pls_golite062009
kinase activity 2.51764884377633 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.42131903112048 bayes_pls_golite062009
protein serine/threonine kinase activity 2.33489933634525 bayes_pls_golite062009
transferase activity 1.67087201309072 bayes_pls_golite062009
binding 1.59201750877601 bayes_pls_golite062009
protein kinase binding 1.55645492554893 bayes_pls_golite062009
kinase binding 1.51987207051111 bayes_pls_golite062009
substrate-specific channel activity 1.48805696223451 bayes_pls_golite062009
ion transmembrane transporter activity 1.42659032865959 bayes_pls_golite062009
protein binding 1.3720766721692 bayes_pls_golite062009
ion channel activity 1.14619697479951 bayes_pls_golite062009
passive transmembrane transporter activity 1.11456280812043 bayes_pls_golite062009
channel activity 1.11456280812043 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.09419636675027 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.02079783694575 bayes_pls_golite062009
gated channel activity 0.86824333497311 bayes_pls_golite062009
cation transmembrane transporter activity 0.808206044972536 bayes_pls_golite062009
protein kinase regulator activity 0.49157430744145 bayes_pls_golite062009
kinase regulator activity 0.44703917270274 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.40953951047033 bayes_pls_golite062009
enzyme binding 0.36894766018324 bayes_pls_golite062009
PDZ domain binding 0.26231792801562 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.24227155451288 bayes_pls_golite062009
catalytic activity 0.181756622780318 bayes_pls_golite062009
voltage-gated ion channel activity 0.17933752392049 bayes_pls_golite062009
voltage-gated channel activity 0.17526760456624 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle