| Protein: | ort-PA |
| Organism: | Drosophila melanogaster |
| Length: | 485 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ort-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
355.0 | [0..21] | [482..97] |
|
Region A: Residues: [1-345] |
1 11 21 31 41 51
| | | | | |
1 MVFQIIILVI CTICMKHYAK GEFQQSLAIT DILPEDIKRY DKMRPPKKEG QPTIVYFHVT 60
61 VMGLDSIDEN SMTYVADVFF AQTWKDHRLR LPENMTQEYR LLEVDWLKNM WRPDSFFKNA 120
121 KSVTFQTMTI PNHYMWLYKD KTILYMVKLT LKLSCIMNFA IYPHDTQECK LQMESLSHTT 180
181 DDLIFQWDPT TPLVVDENIE LPQVALIRNE TADCTQVYST GNFTCLEVVF TLKRRLVYYV 240
241 FNTYIPTCMI VIMSWVSFWI KPEAAPARVT LGVTSLLTLS TQHAKSQSSL PPVSYLKAVD 300
301 AFMSVCTVFV FMALMEYCLI NIVLSDTPIP KPMAYPPKPV AGDGP
|
| Detection Method: |  |
| Confidence: | 63.154902 |
| Match: | 2bg9E |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [346-485] |
1 11 21 31 41 51
| | | | | |
1 KKEGEGAPPG GSNSTASKQQ ATMLPLADEK IEKIEKIFDE MTKNRRIVTT TRRVVRPPLD 60
61 ADGPWIPRQE SRIILTPTIA PPPPPPQPAA PEPELPKPKL TPAQERLKRA IYIDRSSRVL 120
121 FPALFASLNG IYWCVFYEYL
|
| Detection Method: | |
| Confidence: | 35.69897 |
| Match: | 1oedE |
| Description: | Acetylcholine receptor protein, gamma chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| gated channel activity | 10.2551793466975 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 10.2376763289131 | bayes_pls_golite062009 |
| channel activity | 10.2376763289131 | bayes_pls_golite062009 |
| cation channel activity | 10.2347362632182 | bayes_pls_golite062009 |
| ion channel activity | 10.2333303544163 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.0849981425464 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 9.75096408199907 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 9.75096408199907 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 9.54895878381443 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 8.93153903385632 | bayes_pls_golite062009 |
| acetylcholine binding | 8.89748048814778 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 8.63094174477134 | bayes_pls_golite062009 |
| amine binding | 7.31839282808397 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.38791849115967 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| receptor activity | 4.1874951666279 | bayes_pls_golite062009 |
| chloride channel regulator activity | 4.14525491522551 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.06660325759774 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 4.04952633312337 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 3.95647263626091 | bayes_pls_golite062009 |
| molecular transducer activity | 3.94320057935526 | bayes_pls_golite062009 |
| signal transducer activity | 3.94320057935526 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.65985905824027 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.15685612471345 | bayes_pls_golite062009 |
| binding | 2.05702964713174 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.05103642365448 | bayes_pls_golite062009 |
| transporter activity | 1.77814143299132 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.70511083689232 | bayes_pls_golite062009 |
| drug binding | 1.40945164171836 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| 0.56308303460044 | bayes_pls_golite062009 | |
| channel regulator activity | 0.54858839706786 | bayes_pls_golite062009 |
| protein binding | 0.387628241194027 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 0.302120334605641 | bayes_pls_golite062009 |
