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View Structure Prediction Details

Protein: Cbp20-PA
Organism: Drosophila melanogaster
Length: 154 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Cbp20-PA.

Description E-value Query
Range
Subject
Range
gi|157118269, gi... - gi|94468876|gb|ABF18287.1| RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I co...
133.0 [0..13] [154..1]
gi|76650112 - gi|76650112|ref|XP_876288.1| PREDICTED: similar to Heterogeneous nuclear ribonucleoprotein A1 (Helix...
133.0 [0..18] [151..2]
gi|118793887, gi... - gi|118793887|ref|XP_321133.3| ENSANGP00000018356 [Anopheles gambiae str. PEST], gi|116116027|gb|EAA0...
132.0 [0..25] [154..7]
gi|94373120 - gi|94373120|ref|XP_982196.1| PREDICTED: similar to heterogeneous nuclear ribonucleoprotein A3 [Mus m...
131.0 [0..21] [154..26]
PABP2_ARATH - Polyadenylate-binding protein 2 OS=Arabidopsis thaliana GN=PAB2 PE=1 SV=1
131.0 [0..6] [153..191]
gi|18858617, gi|... - gi|68085524|gb|AAH65965.2| ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D...
131.0 [0..3] [150..17]
gi|91093321 - gi|91093321|ref|XP_968171.1| PREDICTED: similar to CG32169-PA [Tribolium castaneum]
130.0 [0..10] [152..102]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFASVELSSY RDQHFKGSRS EQERSLRDSC TLYVGNLSFY TTEEQIHELF SRCGDVRVIV  60
   61 MGLDKYKKTP CGFCFVEYYV RSEAEAAMRF VNGTRLDDRL IRVDWDAGFV EGRQYGRGKT 120
  121 GGQVRDEYRT DYDAGRGGYG KLLSQKIAPN TDNR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.045757
Match: 1h2tZ
Description: CBP20, 20KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
RNA cap binding 5.43390507836051 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
transporter activity 0.628672636801176 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
transmembrane transporter activity 0.505106991526286 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009
substrate-specific transporter activity 0.182749906784328 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.096231856558874 bayes_pls_golite062009
pyrophosphatase activity 0.059732432409948 bayes_pls_golite062009
snoRNA binding 0.0568636182001701 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0510390778764699 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0484248928275733 bayes_pls_golite062009

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