YRC Public Data Repository - Protein Structure Prediction

Protein:	CG9588-PA
Organism:	Drosophila melanogaster
Length:	220 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG9588-PA.

Description	E-value	Query Range	Subject Range
gi\|60653051, gi\|... - gi\|60653053\|gb\|AAX29221.1\| proteasome 26S subunit 9 [synthetic construct], gi\|60653051\|gb\|AAX29220.1...	152.0	[0..3]	[211..15]
gi\|55666783 - gi\|55666783\|ref\|XP_520655.1\| PREDICTED: proteasome 26S non-ATPase subunit 9 [Pan troglodytes]	152.0	[0..3]	[211..15]
gi\|190690689, gi... - gi\|190690689\|gb\|ACE87119.1\| proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 protein [synt... gi\|12803159, gi\|... - gi\|18543329\|ref\|NP_002804.2\| proteasome 26S non-ATPase subunit 9 [Homo sapiens], gi\|13278912\|gb\|AAH0...	152.0	[0..3]	[211..15]
gi\|109099062 - gi\|109099062\|ref\|XP_001096532.1\| PREDICTED: proteasome (prosome, macropain) 26S subunit, non-ATPase,...	152.0	[0..3]	[211..15]
gi\|229344317, gi... - gi\|229519628\|ref\|ZP_04409071.1\| outer membrane stress sensor protease DegQ [Vibrio cholerae RC9], gi... gi\|229342095, gi... - gi\|229520862\|ref\|ZP_04410284.1\| outer membrane stress sensor protease DegQ [Vibrio cholerae TM 11079... gi\|227080749, gi... - gi\|227080749\|ref\|YP_002809300.1\| protease DO [Vibrio cholerae M66-2], gi\|227008637\|gb\|ACP04849.1\| pr... gi\|229507177, gi... - gi\|229507177\|ref\|ZP_04396683.1\| outer membrane stress sensor protease DegQ [Vibrio cholerae BX 33028... gi\|15640588, gi\|... - gi\|9654996\|gb\|AAF93734.1\| protease DO [Vibrio cholerae O1 biovar El Tor str. N16961], gi\|15640588\|re... gi\|11278798 - pir\|\|F82307 proteinase DO VC0566 [imported] - Vibrio cholerae (strain N16961 serogroup O1) gi\|229606145, gi... - gi\|229606145\|ref\|YP_002876793.1\| outer membrane stress sensor protease DegQ [Vibrio cholerae MJ-1236... gi\|121591583, gi... - gi\|121591583\|ref\|ZP_01678838.1\| protease DO [Vibrio cholerae 2740-80], gi\|121546565\|gb\|EAX56765.1\| p... gi\|124120842, gi... - gi\|153803624\|ref\|ZP_01958210.1\| protease DO [Vibrio cholerae MZO-3], gi\|124120842\|gb\|EAY39585.1\| pro... gi\|153224050, gi... - gi\|153224050\|ref\|ZP_01954195.1\| protease DO [Vibrio cholerae MAK 757], gi\|124117870\|gb\|EAY36613.1\| p... gi\|126518367, gi... - gi\|229509162\|ref\|ZP_04398647.1\| outer membrane stress sensor protease DegQ [Vibrio cholerae B33], gi... gi\|125617304 - gi\|125617304\|gb\|EAZ45876.1\| protease DO [Vibrio cholerae MO10] gi\|153830227, gi... - gi\|153830227\|ref\|ZP_01982894.1\| protease DO [Vibrio cholerae 623-39], gi\|148874287\|gb\|EDL72422.1\| pr... gi\|147673156, gi... - gi\|227116942\|ref\|YP_002818838.1\| protease DO [Vibrio cholerae O395], gi\|227012392\|gb\|ACP08602.1\| pro...	152.0	[0..5]	[219..181]
gi\|59712832, gi\|... - gi\|59712832\|ref\|YP_205608.1\| serine endoprotease DegP (protease Do), periplasmic [Vibrio fischeri ES...	152.0	[0..5]	[219..180]
gi\|121627980, gi... - gi\|75814059\|ref\|ZP_00744710.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai...	151.0	[0..5]	[219..171]
gi\|75825935 - gi\|75825935\|ref\|ZP_00755370.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|75828604, gi\|... - gi\|75828604\|ref\|ZP_00757976.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai...	151.0	[0..5]	[219..138]
gi\|67939397, gi\|... - gi\|67939397\|ref\|ZP_00531900.1\| Peptidase S1, chymotrypsin:PDZ/DHR/GLGF [Chlorobium phaeobacteroides ...	151.0	[0..3]	[219..212]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAGTTTKER LERLINAKKQ LEAQINRNGQ ILAANDNVGM SGPLVDAEGF PRNDIDVYQV  60
   61 RLARQTIICL QNDHKELMNQ IQTLLNQYHS EIATTDPELV NRASALDLDS DRSPGGANIT 120
  121 DLAPARAIVV VNLVSPDSPA ERAGLCAGDA ILRFGSINSG NFKGDLAQIG ELVRNMQSQN 180
  181 VQLKVKRGEQ QLDLILVPKT WSGRGLLGCN IVLPPEAMDH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.69897
Match:	1ky9A
Description:	Protease Do (DegP, HtrA), C-terminal domains; Protease Do (DegP, HtrA), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	4.00482245922158	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	3.80641317919152	bayes_pls_golite062009
endopeptidase activity	3.69721977392816	bayes_pls_golite062009
protein binding	3.40921081688513	bayes_pls_golite062009
binding	3.2595117613307	bayes_pls_golite062009
hydrolase activity	2.69939003844937	bayes_pls_golite062009
transcription regulator activity	2.16834620509051	bayes_pls_golite062009
transcription activator activity	1.37255187012662	bayes_pls_golite062009
transporter activity	0.666562078558936	bayes_pls_golite062009
transmembrane transporter activity	0.510205657363692	bayes_pls_golite062009
enzyme binding	0.46071739042312	bayes_pls_golite062009
ubiquitin-protein ligase activity	0.342817187733892	bayes_pls_golite062009
small conjugating protein ligase activity	0.299572882681276	bayes_pls_golite062009
structural molecule activity	0.153277808949873	bayes_pls_golite062009
substrate-specific transporter activity	0.141613198202921	bayes_pls_golite062009
PDZ domain binding	0.0604467745298803	bayes_pls_golite062009
transcription factor binding	0.0283953080227368	bayes_pls_golite062009
cytoskeletal protein binding	0.0187659836234897	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: