| Protein: | svp-PA |
| Organism: | Drosophila melanogaster |
| Length: | 746 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for svp-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
375.0 | [0..1] | [514..1] |
|
Region A: Residues: [1-190] |
1 11 21 31 41 51
| | | | | |
1 MCASPSTAPG FFNPRPQSGA ELSAFDIGLS RSMGLGVPPH SAWHEPPASL GGHLHAASAG 60
61 PGTTTGSVAT GGGGTTPSSV ASQQSAVIKQ DLSCPSLNQA GSGHHPGIKE DLSSSLPSAN 120
121 GGSAGGHHSG SGSGSGSGVN PGHGSDMLPL IKGHGQDMLT SIKGQPTGCG STTPSSQANS 180
181 SHSQSSNSGS
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [191-282] |
1 11 21 31 41 51
| | | | | |
1 QIDSKQNIEC VVCGDKSSGK HYGQFTCEGC KSFFKRSVRR NLTYSCRGSR NCPIDQHHRN 60
61 QCQYCRLKKC LKMGMRREAV QRGRVPPTQP GL
|
| Detection Method: | |
| Confidence: | 30.39794 |
| Match: | 1dszA |
| Description: | Retinoic acid receptor DNA-binding domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| nucleic acid binding | 3.47256374293954 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription activator activity | 2.9532663930699 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.72967350701574 | bayes_pls_golite062009 |
| protein binding | 2.44501340584871 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.40923942043513 | bayes_pls_golite062009 |
| transcription repressor activity | 1.88834375049208 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.26452462867497 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.68943696300126 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| receptor activity | 0.126253365586995 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.0613150171780344 | bayes_pls_golite062009 |
|
Region A: Residues: [283-582] |
1 11 21 31 41 51
| | | | | |
1 AGMHGQYQIA NGDPMGIAGF NGHSYLSSYI SLLLRAEPYP TSRYGQCMQP NNIMGIDNIC 60
61 ELAARLLFSA VEWAKNIPFF PELQVTDQVA LLRLVWSELF VLNASQCSMP LHVAPLLAAA 120
121 GLHASPMAAD RVVAFMDHIR IFQEQVEKLK ALHVDSAEYS CLKAIVLFTT GKLLDILYKD 180
181 VPALLTKVSA LLGKGSTASN DDVLAVVRDH LDELNRQEQE SQAQQQAPLH LAAFMNCVAG 240
241 VEAAVQQAEQ AQVPTSSASA SVSAPLVPSA GSAFSSCQAK SAGSEMDLLA SLYAQAQATP 300
301
|
| Detection Method: | |
| Confidence: | 60.0 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.52514802829523 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| molecular transducer activity | 1.86480242237659 | bayes_pls_golite062009 |
| signal transducer activity | 1.86480242237659 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| lipid binding | 0.475303782949439 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
|
Region A: Residues: [583-746] |
1 11 21 31 41 51
| | | | | |
1 PSSGGGDASG HNNSSGLGAS LPTQSQSGSS SRNLTASPLS TSLATAPAPA SASAPAPVPT 60
61 SSVAQVPVPA PVPVTSSASS SSLGGGAYQT PSAAAAAAAM FHYQTPPRAA FGSAFDMFHH 120
121 STPFGVGVGH AHALAHSSGS GSASFGSPSY RYSPYSLAGS RWQL
|
| Detection Method: | |
| Confidence: | 1.18 |
| Match: | 2j63A |
| Description: | No description for 2j63A was found. |
