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View Structure Prediction Details

Protein: aur-PA
Organism: Drosophila melanogaster
Length: 411 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aur-PA.

Description E-value Query
Range
Subject
Range
gi|603537, gi|60... - gi|603537|emb|CAA58469.1| aurora [Drosophila melanogaster], gi|603535|emb|CAA58468.1| aurora [Drosop...
342.0 [0..1] [411..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHPSDHVLR PKENAPHRMP EKSAAVHNMQ KNLLLGKKPN SENMAPASKP LPGSSGALIR  60
   61 KPGLGGSNSI ASSEGNNFQK PMVPSVKKTT SEFAAPAPVA PI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [103-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKPESLSKQK PTAASSESSK ELGAASSSAE KEKTKTETQP QKPKKTWELN NFDIGRLLGR  60
   61 GKFGNVYLAR EKESQFVVAL KVLFKRQIGE SNVEHQVRRE IEIQSHLRHP HILRLYAYFH 120
  121 DDVRIYLILE YAPQGTLFNA LQAQPMKRFD ERQSATYIQA LCSALLYLHE RDIIHRDIKP 180
  181 ENLLLGHKGV LKIADFGWSV HEPNSMRMTL CGTVDYLPPE MVQGKPHTKN VDLWSLGVLC 240
  241 FELLVGHAPF YSKNYDETYK KILKVDYKLP EHISKAASHL ISKLLVLNPQ HRLPLDQVMV 300
  301 HPWILAHTQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.30103
Match: 2j4zA
Description: No description for 2j4zA was found.

Predicted functions:

Term Confidence Notes
protein kinase activity 5.17195961442593 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 5.04467222534257 bayes_pls_golite062009
kinase activity 4.85903980916957 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.46123870227889 bayes_pls_golite062009
transferase activity 3.26787750561728 bayes_pls_golite062009
binding 2.31930216202447 bayes_pls_golite062009
tubulin binding 2.18641675163967 bayes_pls_golite062009
cytoskeletal protein binding 2.12615078788254 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
microtubule binding 1.88110801192607 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
actin binding 1.33479685165255 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
structural constituent of cytoskeleton 0.612883428421652 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.391384757497683 bayes_pls_golite062009
pyrophosphatase activity 0.351206771811872 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.340617390162297 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.339969855367828 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.282849280638519 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
actin filament binding 0.2403700250846 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.0556163711947139 bayes_pls_golite062009
transmembrane receptor activity 0.00652065412910241 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle