| Protein: | Mcm5-PA |
| Organism: | Drosophila melanogaster |
| Length: | 733 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Mcm5-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
582.0 | [0..1] | [733..1] |
|
Region A: Residues: [1-302] |
1 11 21 31 41 51
| | | | | |
1 MEGFDDAGVF FSDNFGGDNQ QDAQINLQAV KKKYKEFIRT FNEENFFYKY RDTLKRNYLN 60
61 GRYFLEIEME DLVGFDETLA DKLNKQPTEH LEIFEEAARE VADEITAPRP EHEEHMHDIQ 120
121 ILLSSNANPT NIRQLKSDCV SKLVKIAGII VAASGISAKA TRMSIQCLSC STVIPNLKVN 180
181 PGLEGYALPR KCNTEQAGRP KCPLDPFFIM PDKCKCVDFQ TLKLQELPDF VPQGEIPRHL 240
241 QLFCDRSLCE RVVPGNRVLI QGIYSIRKVG KPSRRDGREK AVVGVRAPYM RVVGITVDSE 300
301 GA
|
| Detection Method: |  |
| Confidence: | 43.39794 |
| Match: | 1ltlA |
| Description: | DNA replication initiator (cdc21/cdc54) N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telomeric DNA binding | 4.81350293592083 | bayes_pls_golite062009 |
| telomerase inhibitor activity | 4.48082903165152 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 4.34033743483519 | bayes_pls_golite062009 |
| nucleic acid binding | 4.29626483284963 | bayes_pls_golite062009 |
| DNA binding | 3.71771169141041 | bayes_pls_golite062009 |
| structural constituent of ribosome | 3.51998515668903 | bayes_pls_golite062009 |
| structure-specific DNA binding | 3.48139490984491 | bayes_pls_golite062009 |
| single-stranded DNA binding | 3.43027351695641 | bayes_pls_golite062009 |
| structural molecule activity | 3.29857127235306 | bayes_pls_golite062009 |
| binding | 2.83465364476231 | bayes_pls_golite062009 |
| transcription regulator activity | 2.10110937001387 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.9581702424972 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.84819558112187 | bayes_pls_golite062009 |
| translation regulator activity | 1.46320772716954 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 1.40718318783582 | bayes_pls_golite062009 |
| transcription repressor activity | 1.30343463892105 | bayes_pls_golite062009 |
| translation initiation factor activity | 1.27539679024898 | bayes_pls_golite062009 |
| transcription activator activity | 1.24141936405635 | bayes_pls_golite062009 |
| protein binding | 1.20309946451799 | bayes_pls_golite062009 |
| RNA polymerase activity | 1.19766815287926 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 1.19766815287926 | bayes_pls_golite062009 |
| ribonuclease activity | 1.19236946227657 | bayes_pls_golite062009 |
| transcription factor activity | 1.14242112812892 | bayes_pls_golite062009 |
| DNA helicase activity | 1.12203697857261 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.638831894247026 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.635129001787169 | bayes_pls_golite062009 |
| nuclease activity | 0.57381531077345 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 0.474251377131502 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 0.47336621289748 | bayes_pls_golite062009 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 0.47336621289748 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 0.325774164899685 | bayes_pls_golite062009 |
| four-way junction helicase activity | 0.31769813397725 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.314881439089948 | bayes_pls_golite062009 |
| exonuclease activity | 0.28313884527829 | bayes_pls_golite062009 |
| transferase activity | 0.249054945579328 | bayes_pls_golite062009 |
| RNA binding | 0.18502033889261 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 0.125256208482441 | bayes_pls_golite062009 |
| exoribonuclease activity | 0.109774918833391 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.0954216620147701 | bayes_pls_golite062009 |
| DEAD/H-box RNA helicase binding | 0.0627405398613412 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.0179535526984695 | bayes_pls_golite062009 |
| helicase activity | 0.0121541775159524 | bayes_pls_golite062009 |
|
Region A: Residues: [303-733] |
1 11 21 31 41 51
| | | | | |
1 GAISRYSNIT SDEEEHFRRM AASGDIYERL SQSLAPSIFG SRDIKKAITC MLFGGSRKRL 60
61 PDGLCRRGDI NVLLLGDPGT AKSQLLKFVE KVAPIAVYTS GKGSSAAGLT ASVMKDPQTR 120
121 NFVMEGGAMV LADGGVVCID EFDKMREDDR VAIHEAMEQQ TISIAKAGIT TTLNSRCSVL 180
181 AAANSIFGRW DDTKGEENID FMPTILSRFD MIFIVKDIHD ESRDITLAKH IINVHLSSNK 240
241 SAPSEPAEGE ISLSTFKKYI HYCRTHCGPR LSEAAGEKLK SRYVLMRSGA GQQEKASDKR 300
301 LSIPITVRQL EAVIRISESL AKIRLQPFAT DEHVNEALRL FQVSTLDAAM TGSLAGAEGF 360
361 TTEEDQETLN RIEKQLKRRF AIGSQVSEQN ILQDFLRQKY EERTVMKVIH TMIRRGELQH 420
421 RMQRKMLYRI C
|
| Detection Method: | |
| Confidence: | 18.221849 |
| Match: | 2dhrA |
| Description: | No description for 2dhrA was found. |
