YRC Public Data Repository - Protein Structure Prediction

Protein:	CG6833-PB, CG6833-PA
Organism:	Drosophila melanogaster
Length:	290 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6833-PB, CG6833-PA.

Description	E-value	Query Range	Subject Range
DPO3_STRPN - DNA polymerase III polC-type OS=Streptococcus pneumoniae GN=polC PE=3 SV=1 DPO3_STRPN - DNA polymerase III PolC-type OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN...	229.0	[0..1]	[280..304]
DPO3_STRR6 - DNA polymerase III PolC-type OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) GN=polC PE=3 SV=... DPO3_STRP2 - DNA polymerase III PolC-type OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) GN=polC... gi\|25312571 - pir\|\|C97903 DNA-directed DNA polymerase (EC 2.7.7.7) III, alpha chain [imported] - Streptococcus pne...	228.0	[0..1]	[280..304]
gi\|13622981, gi\|... - gi\|15675759\|ref\|NP_269933.1\| DNA polymerase III PolC [Streptococcus pyogenes M1 GAS], gi\|13622981\|gb... DPO3_STRPY - (Q9FDF9) DNA polymerase III polC-type (EC 2.7.7.7) (PolIII) DPO3_STRP1 - DNA polymerase III PolC-type OS=Streptococcus pyogenes serotype M1 GN=polC PE=3 SV=1	227.0	[0..1]	[287..306]
gi\|71911485, gi\|... - gi\|71911485\|ref\|YP_283035.1\| DNA polymerase III PolC [Streptococcus pyogenes MGAS5005], gi\|71854267\|...	227.0	[0..1]	[287..306]
gi\|209560099, gi... - gi\|209560099\|ref\|YP_002286571.1\| DNA polymerase III alpha subunit [Streptococcus pyogenes NZ131], gi... gi\|56808719 - gi\|56808719\|ref\|ZP_00366439.1\| COG2176: DNA polymerase III, alpha subunit (gram-positive type) [Stre...	226.0	[0..1]	[287..306]
gi\|152976184, gi... - gi\|89203212\|ref\|ZP_01181903.1\| DNA polymerase III, epsilon subunit:DNA polymerase III, alpha subunit...	226.0	[0..26]	[286..318]
DPO3_STRPF - DNA polymerase III PolC-type OS=Streptococcus pyogenes serotype M4 (strain MGAS10750) GN=polC PE=3 S...	226.0	[0..1]	[287..306]
DPO3_STRP6 - DNA polymerase III PolC-type OS=Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)... DPO3_STRP6 - DNA polymerase III polC-type OS=Streptococcus pyogenes serotype M6 GN=polC PE=3 SV=1	225.0	[0..1]	[287..306]
gi\|62528490 - gi\|62528490\|ref\|ZP_00389743.1\| COG2176: DNA polymerase III, alpha subunit (gram-positive type) [Stre...	225.0	[0..1]	[287..229]

Back

Predicted Domain #1

Region A:
Residues: [1-111]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATPRQKQF DMNRSRANNL DSSRSGSANN KNTTDSTKNV VSPQHNQRKL QASMERLQVQ  60
   61 QVNTSRRAAG SNWMAAAGGG AAAAAGSENQ DAKATESAPL SKSARMRMKK K

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [112-290]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHRNRILAMD CEMVGVGHNT RDDMLARVSI VNRMGHVLLD KYVKPRKEVT DYRTSVSGIR  60
   61 PQDIANGEDF AAVQNEVMKL IHGRILVGHG LRNDLAVLGI RHPFHDIRDT SHYKPLCKLI 120
  121 SNTHTPSLKR LTKAVLGQEI QTGEHNSVED ARAAMGIYNR VAVDWEKYLE KKRHQQQHY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.522879
Match:	1wljA
Description:	human ISG20
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribonuclease activity	5.30591758406946	bayes_pls_golite062009
exoribonuclease activity	3.71639182685131	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	3.59362615133405	bayes_pls_golite062009
3'-5'-exoribonuclease activity	3.1992647486402	bayes_pls_golite062009
exonuclease activity	3.13676176369406	bayes_pls_golite062009
nuclease activity	3.11657409772275	bayes_pls_golite062009
ribonuclease H activity	2.91966688044755	bayes_pls_golite062009
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity	2.75003136922541	bayes_pls_golite062009
endonuclease activity	2.63074055051349	bayes_pls_golite062009
endoribonuclease activity	2.59247838057313	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.57498413015114	bayes_pls_golite062009
hydrolase activity	2.41899414621161	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2.04408785855894	bayes_pls_golite062009
3'-5' exonuclease activity	1.44123900197846	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
nucleic acid binding	1.23371034593624	bayes_pls_golite062009
protein binding	1.16870279238939	bayes_pls_golite062009
deoxyribonuclease activity	1.1219517187744	bayes_pls_golite062009
transcription regulator activity	1.10433412699603	bayes_pls_golite062009
DNA binding	0.860359347662869	bayes_pls_golite062009
binding	0.762139256580538	bayes_pls_golite062009
DNA polymerase activity	0.717600245625866	bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters	0.708753843279937	bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.598360955770972	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.568273228950698	bayes_pls_golite062009
	0.49473250705373	bayes_pls_golite062009
transcription factor activity	0.332903382446869	bayes_pls_golite062009
exodeoxyribonuclease activity	0.278838342302102	bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.261428436029202	bayes_pls_golite062009
structure-specific DNA binding	0.0701825322473915	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.00214157813118243	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: