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Protein Overview: DPO3_STRPN

General Information:
Name(s) found: DPO3_STRPN [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
SHOW ALL
  • DNA polymerase III polC-type OS=Streptococcus pneumoniae GN=polC PE=3 SV=1 [Swiss-Prot]
    • Organism: Streptococcus pneumoniae
    Length: 1463 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSFEILMN QLGMPAEMRQ APALAQANIE RVVVHKISKV WEFHFVFSNI LPIEIFLELK  60
   61 KGLSEEFSKT GNKAVFEIKA RSQEFSNQLL QSYYREAFSE GPCASQGFKS LYQNLQVRAE 120
  121 GNQLFIEGSE AIDKEHFKKN HLPNLAKQLE KFGFPTFNCQ VEKNDVLTQE QEEAFHAENE 180
  181 QIVQAANEEA LRAMEQLEQM APPPAEEKPA FDFQAKKAAA KPKLDKAEIT PMIEVTTEEN 240
  241 RLVFEGVVFD VEQKVTRTGR VLINFKMTDY TSSFSMQKWV KNEEEAQKFD LIKKNSWLRV 300
  301 RGNVEMNNFT RDLTMNVQDL QEVVHYERKD LMPEGERRVE FHAHTNMSTM DALPEVEEIV 360
  361 ATAAKWGHKA VAITDHGNVQ SFPHGYKAAK KAGIQLIYGM EANIVEDRVP IVYNEVEMDL 420
  421 SEATYVVFDV ETTGLSAIYN DLIQVAASKM YKGNVIAEFD EFINPGHPLS AFTTELTGIT 480
  481 DDHVKNAKPL EQVLQEFQEF CKDTVLVAHN ATFDVGFMNA NYERHDLPKI SQPVIDTLEF 540
  541 ARNLYPEYKR HGLGPLTKRF GVALEHHHMA NYDAEATGRL LFIFIKEVAE KHGVTDLARL 600
  601 NIDLISPDSY KKARIKHATI YVKNQVGLKN IFKLVSLSNT KYFEGVPRIP RTVLDAHREG 660
  661 LILGSACSEG EVFDVVVSQG VDAAVEVAKY YDFIEVMPPA IYAPLIAKEQ VKDMEELQTI 720
  721 IKSLIEVGDR LGKPVLATGN VHYIEPEEEI YREIIVRSLG QGAMINRTIG HGEHAQPAPL 780
  781 PKAHFRTTNE MLDEFAFLGE ELARKLVIEN TNALAEIFES VEVVKGDLYT PFIDKAEETV 840
  841 AELTYKKAFE IYGNPLPDIV DLRIEKELTS ILGNGFAVIY LASQMLVQRS NERGYLVGSR 900
  901 GSVGSSFVAT MIGITEVNPL SPHYVCGQCQ YSEFITDGSY GSGFDMPHKD CPNCGHKLSK 960
  961 NGQDIPFETF LGFDGDKVPD IDLNFSGEDQ PSAHLDVRDI FGEEYAFRAG TVGTVAAKTA1020
 1021 YGFVKGYERD YGKFYRDAEV ERLAQGAAGV KRTTGQHPGG IVVIPNYMDV YDFTPVQYPA1080
 1081 DDVTAEWQTT HFNFHDIDEN VLKLDVLGHD DPTMIRKLQD LSGIDPNKIP MDDEGVMALF1140
 1141 SGTDVLGVTP EQIGTPTGML GIPEFGTNFV RGMVDETHPT TFAELLQLSG LSHGTDVWLG1200
 1201 NAQDLIKQGI ADLSTVIGCR DDIMVYLMHA GLEPKMAFTI MERVRKGLWL KISEEERNGY1260
 1261 IEAMKANKVP EWYIESCGKI KYMFPKAHAA AYVMMALRVA YFKVHHPIYY YCAYFSIRAK1320
 1321 AFDIKTMGAG LEVIKRRMEE ISEKRKNNEA SNVEIDLYTT LEIVNEMWER GFKFGKLDLY1380
 1381 CSQATEFLID GDTLIPPFVA MDGLGENVAK QLVRAREEGE FLSKTELRKR GGLSSTLVEK1440
 1441 MDEMGILGNM PEDNQLSLFD ELF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..332] PSI-BLAST 4.30103 No description for 2fkjA was found.
    2 View Details [333..432] FFAS03 3.05 Hypothetical protein YcdX
    3 View Details [433..533] PSI-BLAST 26.39794 No description for 2guiA was found.
    4 View Details [534..1463] PSI-BLAST 1000.0 No description for 2hnhA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • DNA polymerase activity
    		•  7.87431862983329 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  7.78411937387917 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  5.3880945520411 bayes_pls_golite062009
  • exonuclease activity
    		•  2.86892175148145 bayes_pls_golite062009
  • nuclease activity
    		•  2.84202779131927 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.94077739152313 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.87431870698721 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.87430802282815 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.75713164321634 bayes_pls_golite062009
  • transferase activity
    		•  1.47288345517763 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.41871623152578 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • endonuclease activity
    		•  0.935348031740788 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.782108781904855 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.77421125364834 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.64268174969672 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  0.48776342704945 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.26279899872348 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.251640316483416 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.18445559832317 bayes_pls_golite062009
  • single-stranded DNA specific 3'-5' exodeoxyribonuclease activity
    		•  0.1355017328177 bayes_pls_golite062009
  • binding
    		•  0.122249780594036 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle