| Protein: | gi|21645643, gi|... |
| Organism: | Drosophila melanogaster |
| Length: | 1218 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|21645643, gi|....
| Description | E-value | Query Range |
Subject Range |
|
|
678.0 | [0..124] | [1178..1] |
|
Region A: Residues: [1-213] |
1 11 21 31 41 51
| | | | | |
1 MMAISAATPS LRRATAIDGD ADADADADAG ADGNDNENHV DGYSDDDDDD ERWLRAARAQ 60
61 KVQKAQTQAY AAHNDRPQTK TTVAIRQNNG SNKSNSNSNS KCNSSSSNNN NNYKSATTSQ 120
121 SNINHRLAPR ASFPEIMQPR LSLNGLLNPS LMPSPRPLYR DHSSRSINPL TAYEQQMAEL 180
181 DGSFYASNAG YLGAGMGGSA GDGTTCTNLT VGG
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [214-281] |
1 11 21 31 41 51
| | | | | |
1 GSTGGGAMAS GGGGTSAQVG GGGGGSGGGG AAIHTTELSI TPTMAGDEQF IDLGSLRRFS 60
61 IDRQSFLD
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [282-464] |
1 11 21 31 41 51
| | | | | |
1 LGPKFGMTQP KFGQSVSQQG FFTSHDSLAT PCASRASNSH MATVSTASEM DLLHNKQRNK 60
61 SRGRLKTAAS GDQPLLGTWN RSTGRGSQDN TLAGGGATSL AMGGHNQYGG NYCNGTDRYP 120
121 RSRSQQQGHH NAAQQAHHPY QLQHSASTVS HHPHAHGPPS QGGPGGPGPP HGGHPHHPHH 180
181 GGA
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [465-755] |
1 11 21 31 41 51
| | | | | |
1 GSGGGSGPGS HGGQPHHQKP RRTASQRIRA ATAARKLHFV FDPAGRLCYY WSMVVSMAFL 60
61 YNFWVIIYRF AFQEINRRTI AIWFCLDYLS DFLYLIDILF HFRTGYLEDG VLQTDALKLR 120
121 THYMNSTIFY IDCLCLLPLD FLYLSIGFNS ILRSFRLVKI YRFWAFMDRT ERHTNYPNLF 180
181 RSTALIHYLL VIFHWNGCLY HIIHKNNGFG SRNWVYHDSE SADVVKQYLQ SYYWCTLALT 240
241 TIGDLPKPRS KGEYVFVILQ LLFGLMLFAT VLGHVANIVT SVSAARKEFQ A
|
| Detection Method: | |
| Confidence: | 9.0 |
| Match: | 2a79B |
| Description: | Mammalian Shaker Kv1.2 potassium channel- beta subunit complex |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [756-967] |
1 11 21 31 41 51
| | | | | |
1 KLDGVKTYMR MRRVPNHLQV KVIKWFDYLW LTQKCSDEER AVSCLPDKLK AEIAINVHLD 60
61 TLKRVEIFQN TEAGFLCELV LRLRPVLFSP GDYICRKGEV GKEMYIVNRG RLQVVADNGK 120
121 TVMASLKAGS YFGEISILNM GTAGNRRTAS VRSVGYSDLF VLSKKDMWDV LKEYPAARVR 180
181 LESIAVKRLE KYKKAPLEKV KYFNVVAMGR CQ
|
| Detection Method: | |
| Confidence: | 21.522879 |
| Match: | 1q3eA |
| Description: | HCN2J 443-645 in the presence of cGMP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cyclic nucleotide-gated ion channel activity | 10.1422916734545 | bayes_pls_golite062009 |
| intracellular cyclic nucleotide activated cation channel activity | 10.1422916734545 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 9.72053268940283 | bayes_pls_golite062009 |
| intracellular cGMP activated cation channel activity | 9.19973076787954 | bayes_pls_golite062009 |
| ion channel activity | 8.54258173089828 | bayes_pls_golite062009 |
| gated channel activity | 8.40583491856766 | bayes_pls_golite062009 |
| channel activity | 8.39905773163311 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 8.39905773163311 | bayes_pls_golite062009 |
| substrate-specific channel activity | 8.39470084162975 | bayes_pls_golite062009 |
| cation channel activity | 8.37340171056317 | bayes_pls_golite062009 |
| cGMP binding | 7.7575871125398 | bayes_pls_golite062009 |
| ligand-gated channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| cyclic nucleotide binding | 7.37322432929433 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 7.27305202954784 | bayes_pls_golite062009 |
| GMP binding | 5.49455172024846 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 4.92543918512794 | bayes_pls_golite062009 |
| voltage-gated channel activity | 4.90247452112447 | bayes_pls_golite062009 |
| intracellular cAMP activated cation channel activity | 3.95109938608832 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 3.17407714154852 | bayes_pls_golite062009 |
| potassium channel activity | 3.16645830461177 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.68223244325599 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.45301353888223 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 2.42821009576643 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.29036912617062 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.1888705807099 | bayes_pls_golite062009 |
| binding | 1.39247933044015 | bayes_pls_golite062009 |
| protein binding | 0.71319432010926 | bayes_pls_golite062009 |
| molecular transducer activity | 0.685020633246238 | bayes_pls_golite062009 |
| signal transducer activity | 0.685020633246238 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.362412435891451 | bayes_pls_golite062009 |
| transporter activity | 0.0214385136840991 | bayes_pls_golite062009 |
|
Region A: Residues: [968-1033] |
1 11 21 31 41 51
| | | | | |
1 STPGLVESCG RTSLEEMWLP PATAGASSLM HHHQALQQQH QASQQQPHRQ ESTQTSSQTH 60
61 GYSPRS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1034-1218] |
1 11 21 31 41 51
| | | | | |
1 YADRLARATD SPRSVSPSAH GSEERPRSRT TSHHSIRPQS QPSHTGHICD SSSQLECYGA 60
61 GVGGAGGGTT PLLGSHEVLE DEIKRLRERL HTVESENQAL NTKLSQQQWD LENRLAEIEM 120
121 QICGVSSTSS VDPENETEEL ERNRERAAAA IQQQEDRKDR ERKAQRGRPI ESATGSQSCA 180
181 KYFSL
|
| Detection Method: | |
| Confidence: | 1.06 |
| Match: | 1ei3B |
| Description: | Fibrinogen |
Matching Structure (courtesy of the PDB): |
|
