| Protein: | FBpp0305371, lack-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1061 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0305371, lack-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
610.0 | [0..274] | [1061..150] |
|
Region A: Residues: [1-184] |
1 11 21 31 41 51
| | | | | |
1 MNKLDYPRRN GTHKVRITIL CARNLARKDL FRLPDPFAKV QVDGTGQVYS TEISKSSLDP 60
61 KWNAHYDLFL GIGDAITITV WNQRKIHKGS GFLGCVRIPA FNIQSLKGAG FQRLDLGKLS 120
121 PDDDELVRGQ IIISLLSKDG PSSGNPLAIV GPSGDVRGPS EDDSSEDSLP EGWEERRTDN 180
181 GRVY
|
| Detection Method: |  |
| Confidence: | 28.69897 |
| Match: | 2jqzA |
| Description: | No description for 2jqzA was found. |
|
Region A: Residues: [185-392] |
1 11 21 31 41 51
| | | | | |
1 YVNHATKSTQ WDRPRQPGVV GSSHATSPQQ RHNTHNGNSG DRQAPAGPTR STTCTNLMNN 60
61 GHRSRDLSVT ASDERRHSTE ILSSVGKENT SPTTPVSATT TPGKKTSSSN SSSAGGRTLE 120
121 QRPTNEPATP TSSTTSASVR LHSNDNHVKT PKHQTNGHAP PESTPTSPTG QQNYVNGNAQ 180
181 NGSTSGNGSG QAAQPQSASN GWTQEDAA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [393-493] |
1 11 21 31 41 51
| | | | | |
1 TTTSPSTTTS PPRHSQSPPT PNISPPASVT PSANGNVHSP NANSTPAGSG GGSRSYTAAT 60
61 PGQRSQRRSS RQQGEESSTR RRSSRGTRNG GTSGGGGGGG S
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [494-653] |
1 11 21 31 41 51
| | | | | |
1 GQRYASAAIA AANQAARPFL DLPPGYEMRT TQQGQVYFYH IPTGVSTWHD PRIPRDFDTQ 60
61 HLTLDAIGPL PSGWEQRKTA SGRVYFVDHN NRTTQFTDPR LSGSILQMIR RGTVPPTSAA 120
121 NAGTPAPPSA TPATPSAAAA VPPQATPASN ATPTTLTTTT
|
| Detection Method: | |
| Confidence: | 3.69897 |
| Match: | 1tk7A |
| Description: | NMR structure of WW domains (WW3-4) from Suppressor of Deltex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| proline-rich region binding | 2.77294348104858 | bayes_pls_golite062009 |
| binding | 2.62219069341981 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 2.59532734096591 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 2.41863405676058 | bayes_pls_golite062009 |
| transcription factor binding | 1.96854466908038 | bayes_pls_golite062009 |
| histone methyltransferase activity | 1.90194027965368 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.6967322982151 | bayes_pls_golite062009 |
| transcription regulator activity | 1.48697365532578 | bayes_pls_golite062009 |
| protein binding | 1.46903005775608 | bayes_pls_golite062009 |
| transcription activator activity | 1.19192967543742 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 1.14806422628668 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 1.14806422628668 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 1.14806422628668 | bayes_pls_golite062009 |
| protein methyltransferase activity | 1.121001087082 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.10202813119932 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.04492347407385 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 0.568363753662296 | bayes_pls_golite062009 |
| transcription repressor activity | 0.2295693429366 | bayes_pls_golite062009 |
| catalytic activity | 0.210712504691113 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K36 specific) | 0.173723075520888 | bayes_pls_golite062009 |
|
Region A: Residues: [654-1061] |
1 11 21 31 41 51
| | | | | |
1 NPPHRIVPDL PQGLLEGADL LPKYRRDLVG KLRALRTELQ TMQPQSGHCR LEVSRNEIFE 60
61 ESYRLIMKMR AKDMRKRLMV KFKGEEGLDY GGVAREWLHL LSREMLNPQY GLFQYSRDDH 120
121 YTLQINPDSG VNPDHLSYFH FVGRTLGIAV FHGHCLDGGF TTPFYKQLLN KPITLGDIEG 180
181 VDPDLHRSLT WMLESNISGI IESTFSVENN SFGALVVHEL KPGGASIPVT EENKREYVKL 240
241 YVNYRFMRGI EQQFLALQKG FCELIPSHLL RPFDERELEL VIGGISSIDV NDWRNNTRLK 300
301 HCTNETTQVL WFWQVVESYS SEMRARLLQF VTGSSRVPLQ GFRALQGSTG AVGPRLFTIH 360
361 LTADVPTQNL PKAHTCFNRI DLPPYETYQL LCDKLTQAVE ETCGFAVE
|
| Detection Method: | |
| Confidence: | 132.0 |
| Match: | 1zvdA |
| Description: | Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain |
Matching Structure (courtesy of the PDB): |
|
