YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: opa1-like-PB
Organism: Drosophila melanogaster
Length: 933 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for opa1-like-PB.

Description E-value Query
Range
Subject
Range
gi|125811438, gi... - gi|54637049|gb|EAL26452.1| GA21105-PA [Drosophila pseudoobscura], gi|125811438|ref|XP_001361873.1| G...
678.0 [0..1] [933..1]

Back

Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRIYQNTYR RTARKAVVYS TKVACCNHST LCGITSHPRR AQDSGSSSSN GRHRGHEEFL  60
   61 LAGNPARGWQ MPPPSRGYGM LVVRILRGAL KLRYIVLG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [99-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAIGGGVSLS KKYEEWKDGL PNFKWLEDAM PQGERWSQFS RNLIEVGSLV KNAIEVAKDD  60
   61 LKAKTTVAAL GITSDESRKK YEKLQSQVET LQTEIMNVQI KYQKELEKME KENRELRQQY 120
  121 LILKT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 1xzpA
Description: Structure of the GTP-binding protein TrmE from Thermotoga maritima
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [224-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKKTTAKKIK KSLIDMYSEV LDELSGYDTG YTMADHLPRV VVVGDQSSGK TSVLESIAKA  60
   61 RIFPRGSGEM MTRAPVKVTL AEGPYHVAQF RDSDREYDLT KESDLQDLRR DVEFRMKASV 120
  121 RGGKTVSNEV IAMTVKGPGL QRMVLVDLPG IISTMTVDMA SDTKDSIHQM TKHYMSNPNA 180
  181 IILCIQDGSV DAERSNVTDL VMQCDPLGRR TIFVLTKVDL AEELADPDRI RKILSGKLFP 240
  241 MKALGYYAVV TGRGRKDDSI DAIRQYEEDF FKNSKLFHRR GVIMPHQVTS RNLSLAVSDR 300
  301 FWKMVRETIE QQADAFKATR FNLETEWKNN FPRLRESGRD ELFDKAKGEI LDEVVTLSQI 360
  361 SAKKWDDALS TKLWEKLSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.0
Match: 2akaB
Description: Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 3.64858540496165 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.89122312915795 bayes_pls_golite062009
pyrophosphatase activity 2.81593838944939 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.79724985811732 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.79347973548337 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity 2.44176688200537 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
microfilament motor activity 2.38215814751368 bayes_pls_golite062009
binding 2.21604035604783 bayes_pls_golite062009
motor activity 2.1532118704195 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
hydrolase activity 1.40217504818333 bayes_pls_golite062009
actin-dependent ATPase activity 0.990320704369021 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
protein transporter activity 0.712797684532763 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
tubulin binding 0.326239364039846 bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0.28297830193871 bayes_pls_golite062009
macromolecule transmembrane transporter activity 0.28297830193871 bayes_pls_golite062009
plus-end-directed microtubule motor activity 0.226790072388501 bayes_pls_golite062009
microtubule binding 0.225323885896927 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 0.213018989352421 bayes_pls_golite062009
nucleic acid binding 0.194779852865789 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [603-662]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YVFESIYLPA AQSGSQNSFN TMVDIKLRQW AEQALPAKSV EAGWEALQQE FISLMERSKK  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [663-855]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQDHDGIFDQ LKSAVVDEAI RRHSWEDKAI DMLRVIQLNT LEDRFVHDKQ EWDSAVKFLE  60
   61 SSVNAKLVQT EETLAQMFGP GQMRRITHWQ YLTQDQQKRR SVKNELDKIL KNDTKHLPTL 120
  121 THDELTTVRK NLQRDNVDVD TDYIRQTWFP VYRKHFLQQA LQRAKDCRKA YYLYTQQGAE 180
  181 CEISCSDVVL FWR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [856-933]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQQVIKITGN ALRQQVINRE ARRLDKEIKA VLDEFSDDEE KKGYLLTGKR VLLAEELIKV  60
   61 RQIQEKLEEF INSLNQEK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle