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View Structure Prediction Details

Protein: Den1-PA
Organism: Drosophila melanogaster
Length: 215 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Den1-PA.

Description E-value Query
Range
Subject
Range
gi|38347027, gi|... - gi|50922241|ref|XP_471481.1| OSJNBb0115I09.23 [Oryza sativa (japonica cultivar-group)], gi|38347027|...
213.0 [0..8] [210..805]

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Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSNSKADPI SLTFHDSCLR MSDVQLLHGP HWLNDQILSF YYEYLAHMKY KTNADLHFIA  60
   61 PEITQCMKYM GDQELKQLLD QSNTTGKPFI FFALNDNETT DAGGSHWSLL VFSRPEKTFY 120
  121 HFDSYGNNNT GNSLELMNKI KDLLGVRMAK FRPMRCLQQA NGYDCGIHVI CMTDHIADYL 180
  181 NRYEVIDGLP SLHIDTVKAK RTELLKLILS LGGKG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.69897
Match: 2bkqA
Description: NEDD8 protease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine-type peptidase activity 5.93560668185539 bayes_pls_golite062009
small conjugating protein-specific protease activity 5.48721952122524 bayes_pls_golite062009
ubiquitin-specific protease activity 4.73623517114533 bayes_pls_golite062009
ubiquitin thiolesterase activity 3.38737606974088 bayes_pls_golite062009
thiolester hydrolase activity 1.90178501880966 bayes_pls_golite062009
SUMO-specific protease activity 1.6602460763044 bayes_pls_golite062009
peptidase activity 1.39702589518384 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.28597643058503 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.755467947031123 bayes_pls_golite062009
hydrolase activity 0.612664640888088 bayes_pls_golite062009
binding 0.426262567794169 bayes_pls_golite062009
endopeptidase activity 0.366512660710683 bayes_pls_golite062009
cysteine-type endopeptidase activity 0.125393771316362 bayes_pls_golite062009
NEDD8-specific protease activity 0.09564496961635 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle