| Protein: | otk-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1033 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for otk-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
504.0 | [0..21] | [1024..28] |
|
Region A: Residues: [1-604] |
1 11 21 31 41 51
| | | | | |
1 MTARMISICG LVMALMMASV LASSSRFQRV PQSQSVVENE SVKFECESTD SYSELHYDWL 60
61 HNGHRIAYDK RVHQIGSNLH IEAVRRTEDV GNYVCIATNL ASGAREASPP AKLSVIYLES 120
121 ASVQLLGSNR NELLLKCHVE GASGDLEPLE IEWYRNSEKL STWKNVQLDQ HRLIIRQPGS 180
181 EDDGLYRCTA SNAAGRVMSK QGYVYQSSVK CLPRLPRRKN EKMMESWDKQ TFLCRGKRGG 240
241 AAGLEALPAA PEDLRIVQGP IGQSIIKEGE PTALTCLYEL PDELKNQRIQ LRWRKDGKLL 300
301 RQVELGGSAP IPGHSFDSGK DALLREDARL VLHKQNGTLS FASIIASDAG QYQCQLQLEA 360
361 HAPINSSPGI LEVIEQLKFV PQPTSKNLEL DAVVAKVHCK AQGTPTPQVQ WVRDGENTTL 420
421 PDHVEVDANG TLIFRNVNSE HRGNYTCLAT NSQGQINATV AINVVVTPKF SVPPVGPIET 480
481 SEQGTVVMHC QAIGDPKPTI QWDKDLKYLS ENNTDRERFR FLENGTLEIR NVQVEDEGSY 540
541 GCTIGNSAGL KREDVQLVVK TTGDGFAPEE SGGDGFLVTR AVLITMTVAL AYIVLVVGLM 600
601 LWCR
|
| Detection Method: |  |
| Confidence: | 58.30103 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [605-685] |
1 11 21 31 41 51
| | | | | |
1 YRRQARKARL NDLSTKEAGG DQPDVAGNGK GSEQEPCLSK QHNGHSKSRS KSSGDAQKSD 60
61 DTACSQQSRA SKKSAHIYEQ L
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [686-736] |
1 11 21 31 41 51
| | | | | |
1 ALPRSGLSEL IQIGRGEFGD VFVGKLKATL VTSPSDKDAD TEKQHSNSEN G
|
| Detection Method: | |
| Confidence: | 2.25 |
| Match: | 1bygA |
| Description: | Carboxyl-terminal src kinase (csk) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [737-1033] |
1 11 21 31 41 51
| | | | | |
1 SGGSGSGSTT LSTLNEKRRS KTSMDDIEEI KEEEQDQHNQ SGLEQLVLVK ALNKVKDEQA 60
61 CQEFRRQLDL LRAISHKGVV RLFGLCREKD PHYMVLEYTD WGDLKQFLLA TAGKVNTATA 120
121 GSSSPPPLTT SQVLAVAYQI ARGMDAIYRA RFTHRDLATR NCVISSEFIV KVSYPALCKD 180
181 KYSREYHKHR NTLLPIRWLA PECIQEDEYT TKSDIFAYGV VVWELFNQAT KLPHEELTNE 240
241 QVVQRSQAGS LEWSVAEATP DSLREILLSC WVSNPKERPS FSQLGAALSK AMQSAEK
|
| Detection Method: | |
| Confidence: | 52.154902 |
| Match: | 1lufA |
| Description: | Musk tyrosine kinase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 5.63683237027974 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.24105099841813 | bayes_pls_golite062009 |
| kinase activity | 5.02394449930162 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.38615595541751 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.33927583810751 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| binding | 2.10874590528357 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.74324450025139 | bayes_pls_golite062009 |
| transporter activity | 0.710766490066447 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.60324822483033 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.385603245903806 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.371991354471077 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 0.33808087202461 | bayes_pls_golite062009 |
| magnesium ion binding | 0.310771535422373 | bayes_pls_golite062009 |
| kinase binding | 0.26752427107238 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.152203945257581 | bayes_pls_golite062009 |
| MAP kinase activity | 0.0675236791909441 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.0393215018817107 | bayes_pls_golite062009 |
| protein kinase binding | 0.00674998152095019 | bayes_pls_golite062009 |
