Protein: | Hr46-PA, FBpp0297438 |
Organism: | Drosophila melanogaster |
Length: | 487 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hr46-PA, FBpp0297438.
Description | E-value | Query Range |
Subject Range |
|
296.0 | [0..1] | [487..1] |
Region A: Residues: [1-153] |
1 11 21 31 41 51 | | | | | | 1 MYTQRMFDMW SSVTSKLEAH ANNLGQSNVQ SPAGQNNSSG SIKAQIEIIP CKVCGDKSSG 60 61 VHYGVITCEG CKGFFRRSQS SVVNYQCPRN KQCVVDRVNR NRCQYCRLQK CLKLGMSRDA 120 121 VKFGRMSKKQ REKVEDEVRF HRAQMRAQSD AAP |
Detection Method: | |
Confidence: | 20.69897 |
Match: | 2a66A |
Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [154-225] |
1 11 21 31 41 51 | | | | | | 1 DSSVYDTQTP SSSDQLHHNN YNSYSGGYSN NEVGYGSPYG YSASVTPQQT MQYDISADYV 60 61 DSTTYEPRST II |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Term | Confidence | Notes |
vitamin D3 receptor activity | 5.5563493713822 | bayes_pls_golite062009 |
transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
steroid hormone receptor activity | 4.81441024181511 | bayes_pls_golite062009 |
nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
ecdysteroid hormone receptor activity | 4.66615836207965 | bayes_pls_golite062009 |
transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
nuclear hormone receptor binding | 3.91470119037087 | bayes_pls_golite062009 |
ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
binding | 3.85318710398432 | bayes_pls_golite062009 |
transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
hormone receptor binding | 3.79647267365529 | bayes_pls_golite062009 |
protein binding | 3.21524787168952 | bayes_pls_golite062009 |
transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
vitamin D binding | 2.05947211013242 | bayes_pls_golite062009 |
molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
structure-specific DNA binding | 1.56146647486761 | bayes_pls_golite062009 |
double-stranded DNA binding | 1.48246587604476 | bayes_pls_golite062009 |
estrogen receptor activity | 1.47290778095383 | bayes_pls_golite062009 |
retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
promoter binding | 1.16363620574097 | bayes_pls_golite062009 |
transcription activator binding | 1.12331753119132 | bayes_pls_golite062009 |
transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
juvenile hormone binding | 0.814202236506491 | bayes_pls_golite062009 |
protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
steroid hormone receptor binding | 0.754240851368212 | bayes_pls_golite062009 |
protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
estrogen response element binding | 4.73336420190096E-4 | bayes_pls_golite062009 |
Region A: Residues: [226-487] |
1 11 21 31 41 51 | | | | | | 1 DPEFISHADG DINDVLIKTL AEAHANTNTK LEAVHDMFRK QPDVSRILYY KNLGQEELWL 60 61 DCAEKLTQMI QNIIEFAKLI PGFMRLSQDD QILLLKTGSF ELAIVRMSRL LDLSQNAVLY 120 121 GDVMLPQEAF YTSDSEEMRL VSRIFQTAKS IAELKLTETE LALYQSLVLL WPERNGVRGN 180 181 TEIQRLFNLS MNAIRQELET NHAPLKGDVT VLDTLLNNIP NFRDISILHM ESLSKFKLQH 240 241 PNVVFPALYK ELFSIDSQQD LT |
Detection Method: | |
Confidence: | 37.39794 |
Match: | 1k4wA |
Description: | Orphan nuclear receptor ROR-beta |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
vitamin D3 receptor activity | 5.5563493713822 | bayes_pls_golite062009 |
transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
steroid hormone receptor activity | 4.81441024181511 | bayes_pls_golite062009 |
nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
ecdysteroid hormone receptor activity | 4.66615836207965 | bayes_pls_golite062009 |
transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
nuclear hormone receptor binding | 3.91470119037087 | bayes_pls_golite062009 |
ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
binding | 3.85318710398432 | bayes_pls_golite062009 |
transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
hormone receptor binding | 3.79647267365529 | bayes_pls_golite062009 |
protein binding | 3.21524787168952 | bayes_pls_golite062009 |
transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
vitamin D binding | 2.05947211013242 | bayes_pls_golite062009 |
molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
structure-specific DNA binding | 1.56146647486761 | bayes_pls_golite062009 |
double-stranded DNA binding | 1.48246587604476 | bayes_pls_golite062009 |
estrogen receptor activity | 1.47290778095383 | bayes_pls_golite062009 |
retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
promoter binding | 1.16363620574097 | bayes_pls_golite062009 |
transcription activator binding | 1.12331753119132 | bayes_pls_golite062009 |
transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
juvenile hormone binding | 0.814202236506491 | bayes_pls_golite062009 |
protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
steroid hormone receptor binding | 0.754240851368212 | bayes_pls_golite062009 |
protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
estrogen response element binding | 4.73336420190096E-4 | bayes_pls_golite062009 |