YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Su(var)2-10-PD
Organism: Drosophila melanogaster
Length: 601 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Su(var)2-10-PD.

Description E-value Query
Range		 Subject
Range
Su(var)2-10-PH - The gene Suppressor of variegation 2-10 is referred to in FlyBase by the symbol Dmel\Su(var)2-10 (CG...
 575.0 [0..1] [566..1]

Back

Predicted Domain #1
Region A:
Residues: [1-102] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKTRSQTAR TQAENAATSS SPGHQSTSSA PIAVNPFDST KYKECEQMVQ MLRVVELQKI  60
   61 LSFLNISFAG RKTDLQSRIL SFLRTNLELL APKVQEVYAQ SV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1v66A
Description: Solution structure of human p53 binding domain of PIAS-1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [103-209] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEQNATLQYI DPTRMYSHIQ LPPTVQPNPV GLVGSGQGVQ VPGGQMNVVG GAPFLHTHSI  60
   61 NSQLPIHPDV RLKKLAFYDV LGTLIKPSTL VPRNTQRVQE VPFYFTL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [210-339] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPQQATEIAS NRDIRNSSKV EHAIQVQLRF CLVETSCDQE DCFPPNVNVK VNNKLCQLPN  60
   61 VIPTNRPNVE PKRPPRPVNV TSNVKLSPTV TNTITVQWCP DYTRSYCLAV YLVKKLTSTQ 120
  121 LLQRMKTKGV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [340-462] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPADYTRGLI KEKLTEDADC EIATTMLKVS LNCPLGKMKM LLPCRASTCS HLQCFDASLY  60
   61 LQMNERKPTW NCPVCDKPAI YDNLVIDGYF QEVLGSSLLK SDDTEIQLHQ DGSWSTPGLR 120
  121 SET

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1jm7A
Description: brca1 RING domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 5.55686022186257 bayes_pls_golite062009
ubiquitin-protein ligase activity 5.24177189110056 bayes_pls_golite062009
acid-amino acid ligase activity 4.59153177011595 bayes_pls_golite062009
binding 2.78710909602478 bayes_pls_golite062009
transcription regulator activity 2.72498741013971 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.57382484274962 bayes_pls_golite062009
nucleic acid binding 2.32387297115017 bayes_pls_golite062009
DNA binding 2.00904221080834 bayes_pls_golite062009
transcription repressor activity 1.98209395225978 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.82615879438544 bayes_pls_golite062009
protein binding 1.5975811408548 bayes_pls_golite062009
SUMO polymer binding 1.45421060001117 bayes_pls_golite062009
transcription factor activity 1.22579085356684 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
transcription factor binding 1.11842175076436 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.90321253993065 bayes_pls_golite062009
ligase activity 0.63517530468004 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
transcription corepressor activity 0.384990496120483 bayes_pls_golite062009
hydrolase activity 0.295474423132249 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
transcription coactivator activity 0.255669498391574 bayes_pls_golite062009
transcription cofactor activity 0.233838999434784 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
transcription activator activity 0.126093965701234 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [463-601] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QILDTPSKPA QKVEVISDDI ELISDDAKPV KRDLSPAQDE QPTSTSNSET VDLTLSDSDD  60
   61 DMPLAKRRPP AKQAVASSTS NGSGGGQRAY TPAQQPQQSG GNVFKKPQKA EELYKRVHLG 120
  121 VWLRPRKPKP ESSRRPNVG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle