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View Structure Prediction Details

Protein: TWST2_RAT
Organism: Rattus norvegicus
Length: 160 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TWST2_RAT.

Description E-value Query
Range
Subject
Range
gi|93102315 - gi|93102315|dbj|BAE93441.1| myogenic regulatory factor 4 [Bos taurus]
132.0 [0..1] [160..25]
MYF6 - myogenic factor 6 (herculin)
CCDS9019.1_1 - null
gi|109097928 - gi|109097928|ref|XP_001086944.1| PREDICTED: myogenic factor 6 (herculin) [Macaca mulatta]
gi|124000135, gi... - gi|124000135|gb|ABM87576.1| myogenic factor 6 (herculin) [synthetic construct], gi|123993145|gb|ABM8...
gi|114646062 - gi|114646062|ref|XP_001164135.1| PREDICTED: myogenic factor 6 (herculin) [Pan troglodytes]
128.0 [0..1] [160..25]
gi|226724 - gi|226724|prf||1604247A muscle regulatory factor
128.0 [0..1] [160..25]
gi|33355711 - gi|33355711|gb|AAQ16205.1| eukaryotic myogenic factor MYF-6 [Sus scrofa]
127.0 [0..1] [160..25]
MYF6_MOUSE - Myogenic factor 6 OS=Mus musculus GN=Myf6 PE=2 SV=1
122.0 [0..1] [160..25]
gi|157423113, gi... - gi|62857619|ref|NP_001017160.1| myogenic factor 6 [Xenopus (Silurana) tropicalis], gi|157423113|gb|A...
119.0 [0..1] [160..26]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEGSSSPVS PVDSLGTSEE ELERQPKRFG RKRRYSKKSS EDGSPTPGKR GKKGSPSAQS  60
   61 FEELQSQRIL ANVRERQRTQ SLNEAFAALR KIIPTLPSDK LSKIQTLKLA ARYIDFLYQV 120
  121 LQSDEMDNKM TSCSYVAHER LSYAFSVWRM EGAWSMSASH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1r05A
Description: Solution Structure of Max B-HLH-LZ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.39500382187264 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription repressor activity 2.58751248599889 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.42306484786159 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
transcription corepressor activity 2.03674713048499 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
promoter binding 1.56457725225443 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
transcription coactivator activity 1.39260472877067 bayes_pls_golite062009
structure-specific DNA binding 0.3655541712365 bayes_pls_golite062009
double-stranded DNA binding 0.29436315000437 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle