YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|114636476
Organism: Pan troglodytes
Length: 390 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114636476.

Description E-value Query
Range
Subject
Range
gi|76657156, gi|... - gi|76657156|ref|XP_869162.1| PREDICTED: similar to tumor susceptibility protein isoform 1 [Bos tauru...
2.0E-77 [1..390] [1..391]
gi|57103026 - gi|57103026|ref|XP_542525.1| PREDICTED: similar to tumor susceptibility gene 101 isoform 1 [Canis fa...
8.0E-77 [1..390] [1..391]
gi|60820480 - gi|60820480|gb|AAX36537.1| tumor susceptibility gene 101 [synthetic construct]
9.0E-77 [1..390] [1..390]
gi|123985291, gi... - gi|61355224|gb|AAX41116.1| tumor susceptibility gene 101 [synthetic construct], gi|60655269|gb|AAX32...
HGNC:15971|MIM:6... - susceptibility gene 101
gi|12803337 - gi|12803337|gb|AAH02487.1| Tumor susceptibility gene 101 [Homo sapiens]
3.0E-76 [1..390] [1..390]
gi|50747848 - gi|50747848|ref|XP_421014.1| PREDICTED: similar to tumor susceptibility protein 101 [Gallus gallus]
2.0E-74 [4..390] [377..763]
gi|74226691 - gi|74226691|dbj|BAE26996.1| unnamed protein product [Mus musculus]
7.0E-74 [1..390] [1..391]

Back

Predicted Domain #1
Region A:
Residues: [1-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVSESQLKK MVSKYKYRDL TVRETVNVIT LYKDLKPVLD SYVFNDGSSR ELMNLTGTIP  60
   61 VPYRGNTYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP 120
  121 QSDLLGLIQV MIVVFGDEPP VFSRPISASY PPYQATGPPN TSYMPGMPGG ISPYPSGYPP 180
  181 NPSGYPGCPY PPGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.39794
Match: 1kppA
Description: Tumor susceptibility gene 101 (TSG101) UEV domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 6.80727357703118 bayes_pls_golite062009
ubiquitin-protein ligase activity 6.75330204125607 bayes_pls_golite062009
acid-amino acid ligase activity 5.83782824833863 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.8110076681004 bayes_pls_golite062009
transcription regulator activity 2.21355731489173 bayes_pls_golite062009
nucleic acid binding 2.13970605403492 bayes_pls_golite062009
DNA binding 1.95596447916631 bayes_pls_golite062009
ligase activity 1.88059319399119 bayes_pls_golite062009
binding 1.75350658654805 bayes_pls_golite062009
transcription repressor activity 1.5236035191291 bayes_pls_golite062009
catalytic activity 0.891402822028799 bayes_pls_golite062009
SUMO ligase activity 0.843488104298821 bayes_pls_golite062009
protein binding 0.726328463755484 bayes_pls_golite062009
NEDD8 ligase activity 0.715654744941217 bayes_pls_golite062009
protein kinase activity 0.443948654247666 bayes_pls_golite062009
protein serine/threonine kinase activity 0.182854082413338 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.133142640608253 bayes_pls_golite062009
transcription corepressor activity 0.122859425935324 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0501858755083694 bayes_pls_golite062009
kinase activity 0.0500350353657541 bayes_pls_golite062009
transcription activator activity 0.0138208971172455 bayes_pls_golite062009
transcription factor binding 0.0104967529560147 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [195-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYPATTSSQY PSQPPVTTVG PSRDGTISED TIRASLISAV SDKLRWRMKE EMDRAQAELN  60
   61 ALKRTEEDLK KGHQKLEEMV TRLDQEVAEV DKNIELLKKK DEELSSALEK MENQSENNDI 120
  121 DEVIIPTAPL YKQILNLYAE ENAIEDTIFY LGEALRRGVI DLDVFLKHVR LLSRKQFQLR 180
  181 ALMQKARKTA GLSDLY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle