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View Structure Prediction Details

Protein: gi|13435424, gi|...
Organism: Mus musculus
Length: 270 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|13435424, gi|....

Description E-value Query
Range
Subject
Range
gi|74219891, gi|... - gi|74219891|dbj|BAE40529.1| unnamed protein product [Mus musculus], gi|74146914|dbj|BAE41408.1| unna...
390.0 [0..1] [270..1]
RFA2_RAT - (Q63528) Replication protein A 32 kDa subunit (RP-A) (RF-A) (Replication factor-A protein 2) (Fragme...
375.0 [0..5] [270..1]
gi|86438509, gi|... - gi|86438509|gb|AAI12730.1| Replication protein A2, 32kDa [Bos taurus], gi|114051646|ref|NP_001039449...
370.0 [0..1] [270..1]
gi|73950517 - gi|73950517|ref|XP_544465.2| PREDICTED: similar to Replication protein A 32 kDa subunit (RP-A) (RF-A...
367.0 [0..1] [270..99]
gi|114555089 - gi|114555089|ref|XP_513251.2| PREDICTED: similar to Replication protein A 32 kDa subunit (RP-A) (RF-...
360.0 [0..1] [270..129]
RFA2_PONAB - Replication protein A 32 kDa subunit OS=Pongo abelii GN=RPA2 PE=2 SV=1
RFA2_PONPY - Replication protein A 32 kDa subunit - Pongo pygmaeus (Orangutan)
360.0 [0..1] [270..1]
RPA2 - replication protein A2, 32kDa
gi|123998291, gi... - gi|123998291|gb|ABM86747.1| replication protein A2, 32kDa [synthetic construct], gi|123983074|gb|ABM...
359.0 [0..1] [270..1]

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Predicted Domain #1
Region A:
Residues: [1-270]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWNSGFESFS SSTYGGAGGY TQSPGGFGSP TPSQAEKKSR VRAQHIVPCT ISQLLSATLT  60
   61 DEVFRIGDVE ISQVTIVGII RHAEKAPTNI VYKIDDMTAP PMDVRQWVDT DDASGENAVV 120
  121 PPETYVKVAG HLRSFQNKKS LVAFKIIPLE DMNEFTAHIL EVVNSHMMLS KSNSQASAGR 180
  181 PSMSNPGMSE PGNFSGNNFM PANGLTVVQN QVLNLIKACP RPEGLNFQDL RSQLQHMPVP 240
  241 SIKQAVDFLC NEGHIYSTVD DDHFKSTDAE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 2pi2A
Description: No description for 2pi2A was found.

Predicted functions:

Term Confidence Notes
telomeric DNA binding 7.07761964836826 bayes_pls_golite062009
single-stranded telomeric DNA binding 6.04637014849887 bayes_pls_golite062009
telomerase inhibitor activity 5.40477712257453 bayes_pls_golite062009
nucleic acid binding 4.02967008021862 bayes_pls_golite062009
DNA binding 3.62735703519187 bayes_pls_golite062009
single-stranded DNA binding 3.59212997362902 bayes_pls_golite062009
structure-specific DNA binding 3.53214384646348 bayes_pls_golite062009
binding 2.63617204791771 bayes_pls_golite062009
structural constituent of ribosome 2.25006883439646 bayes_pls_golite062009
transcription regulator activity 2.20239961025491 bayes_pls_golite062009
structural molecule activity 2.07809455998137 bayes_pls_golite062009
DNA replication origin binding 1.84819558112187 bayes_pls_golite062009
ribonuclease activity 1.19236946227657 bayes_pls_golite062009
DNA helicase activity 1.12203697857261 bayes_pls_golite062009
transcription factor activity 1.05816813143865 bayes_pls_golite062009
sequence-specific DNA binding 0.86170694706755 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.79554655100991 bayes_pls_golite062009
RNA polymerase activity 0.79554655100991 bayes_pls_golite062009
hydrolase activity 0.724860465280978 bayes_pls_golite062009
DNA-dependent ATPase activity 0.638831894247026 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
DEAD/H-box RNA helicase binding 0.440977654731901 bayes_pls_golite062009
translation regulator activity 0.41164963411369 bayes_pls_golite062009
double-stranded DNA binding 0.378383789953688 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.360862776629591 bayes_pls_golite062009
nucleotidyltransferase activity 0.325774164899685 bayes_pls_golite062009
four-way junction helicase activity 0.31769813397725 bayes_pls_golite062009
RNA binding 0.31028563542112 bayes_pls_golite062009
translation initiation factor activity 0.30211828233765 bayes_pls_golite062009
exonuclease activity 0.28313884527829 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.226916777208049 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.223941674251642 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.125256208482441 bayes_pls_golite062009
exoribonuclease activity 0.109774918833391 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.0954216620147701 bayes_pls_golite062009
protein binding 0.0528188351789111 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.0179535526984695 bayes_pls_golite062009
helicase activity 0.0121541775159524 bayes_pls_golite062009

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