YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|26341284, gi\|...
Organism:	Mus musculus
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|26341284, gi|....

Description	E-value	Query Range	Subject Range
gi\|66267465, gi\|... - gi\|66267465\|gb\|AAH95434.1\| Inhibitor of growth family, member 4 [Homo sapiens], gi\|38201670\|ref\|NP_0...	209.0	[0..1]	[248..1]
gi\|62648155, gi\|... - gi\|62648155\|ref\|XP_216265.3\| PREDICTED: similar to Inhibitor of growth protein 4 (p29ING4) [Rattus n...	206.0	[0..1]	[248..1]
gi\|542154536\|ref... - PREDICTED: inhibitor of growth protein 4 isoform X1 [Zonotrichia albicollis] ING4_CHICK - Inhibitor of growth protein 4 OS=Gallus gallus GN=ING4 PE=2 SV=1 gi\|224043893 - gi\|224043893\|ref\|XP_002196952.1\| PREDICTED: inhibitor of growth family, member 4 [Taeniopygia guttat...	205.0	[0..1]	[248..1]
ING4_MOUSE - Inhibitor of growth protein 4 OS=Mus musculus GN=Ing4 PE=1 SV=2	205.0	[0..1]	[248..1]
gi\|114643145 - gi\|114643145\|ref\|XP_001169091.1\| PREDICTED: inhibitor of growth family, member 4 [Pan troglodytes]	205.0	[0..1]	[248..1]
gi\|94733520, gi\|... - gi\|94733520\|emb\|CAK04218.1\| novel protein similar to vertebrate inhibitor of growth family, member 4...	204.0	[0..1]	[248..1]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKA EIDKLATEYM SSARSLSSEE  60
   61 KLALLRQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESSD 120
  121 YDSSSSKGKK SRTQKEKKAA RARSKGKNSD EE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.976
Match:	1m1jC
Description:	Fibrinogen C-terminal domains; Fibrinogen gamma chain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [153-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APKAAQKKLK LVRTSPEYGM PSVTFGSVHP SDVLDMPVDP NEPTYCLCHQ VSYGEMIGCD  60
   61 NPDCSIEWFH FACVGLTTKP RGKWFCPRCS QERKKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.39794
Match:	1weuA
Description:	Solution structure of PHD domain in ING1-like protein BAC25009
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
histone acetyltransferase activity	7.10262960897544	bayes_pls_golite062009
lysine N-acetyltransferase activity	7.10262960897544	bayes_pls_golite062009
N-acetyltransferase activity	5.0952093808777	bayes_pls_golite062009
	4.93977737347339	bayes_pls_golite062009
	4.75659254650148	bayes_pls_golite062009
N-acyltransferase activity	4.73470737654883	bayes_pls_golite062009
acetyltransferase activity	4.29938591960121	bayes_pls_golite062009
acyltransferase activity	3.59302841227183	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	3.54892905221507	bayes_pls_golite062009
transferase activity, transferring acyl groups	3.34035867339622	bayes_pls_golite062009
histone binding	3.01402804224903	bayes_pls_golite062009
binding	2.93415748500038	bayes_pls_golite062009
transcription regulator activity	2.89424169822343	bayes_pls_golite062009
DNA binding	2.67786232715949	bayes_pls_golite062009
nucleic acid binding	2.6327300364647	bayes_pls_golite062009
protein binding	2.4739446713993	bayes_pls_golite062009
transcription repressor activity	2.13907615882531	bayes_pls_golite062009
transcription activator activity	2.06834170490665	bayes_pls_golite062009
protein deacetylase activity	1.85191754801422	bayes_pls_golite062009
histone deacetylase activity	1.81121374048292	bayes_pls_golite062009
methylated histone residue binding	1.80051107279585	bayes_pls_golite062009
transcription factor activity	1.62385700361588	bayes_pls_golite062009
sequence-specific DNA binding	1.17383679324331	bayes_pls_golite062009
deacetylase activity	0.912057424750107	bayes_pls_golite062009
histone methyltransferase activity	0.476506467104495	bayes_pls_golite062009
protein kinase activity	0.405766438875014	bayes_pls_golite062009
chromatin binding	0.39425178848458	bayes_pls_golite062009
cytoskeletal protein binding	0.327424740985033	bayes_pls_golite062009
nucleosome binding	0.252195940764881	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.14235705491362	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0901653273812402	bayes_pls_golite062009
transcription factor binding	0.0538806851320555	bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific)	0.0490968711985191	bayes_pls_golite062009
kinase activity	0.00387875923819597	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: