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View Structure Prediction Details

Protein: RFA3_MOUSE
Organism: Mus musculus
Length: 121 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFA3_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109473109, gi... - gi|27708842|ref|XP_216097.1| PREDICTED: similar to replication protein A3 [Rattus norvegicus], gi|15...
186.0 [0..1] [121..1]
gi|114612144 - gi|114612144|ref|XP_527665.2| PREDICTED: replication protein A3, 14kDa [Pan troglodytes]
182.0 [0..1] [121..1]
gi|208967282, gi... - gi|60656467|gb|AAX32797.1| replication protein A3 [synthetic construct], gi|208967282|dbj|BAG73655.1...
RPA3 - replication protein A3, 14kDa
182.0 [0..1] [121..1]
gi|77735809, gi|... - gi|77735809|ref|NP_001029599.1| replication protein A3, 14kDa [Bos taurus], gi|74268179|gb|AAI03269....
179.0 [0..1] [120..1]
gi|109067370, gi... - gi|109067372|ref|XP_001086985.1| PREDICTED: similar to replication protein A3, 14kDa isoform 2 [Maca...
179.0 [0..1] [121..1]
gi|73976423 - gi|73976423|ref|XP_538570.2| PREDICTED: similar to replication protein A3, 14kDa [Canis familiaris]
177.0 [0..1] [121..1]
gi|82795935 - gi|82795935|ref|XP_918088.1| PREDICTED: hypothetical protein [Mus musculus]
161.0 [0..1] [121..1]
gi|47940029 - gi|47940029|gb|AAH71377.1| Zgc:56310 protein [Danio rerio]
154.0 [0..1] [114..1]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDIMQLPKA RVNASMLPQY IDRPVCFVGK LEKIHPTGKM FILSDGEGKN GTIELMEPLD  60
   61 EEISGIVEVV GKVTAKATVL CASYTLFKED TNRFDLELYN EAVKIINELP QFFPVGLPQH 120
  121 E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.69897
Match: 2pi2E
Description: No description for 2pi2E was found.

Predicted functions:

Term Confidence Notes
single-stranded DNA binding 3.59212997362902 bayes_pls_golite062009
structure-specific DNA binding 3.53214384646348 bayes_pls_golite062009
nucleic acid binding 3.27576062206528 bayes_pls_golite062009
DNA binding 2.56243510083541 bayes_pls_golite062009
binding 2.24181355929217 bayes_pls_golite062009
ribonuclease activity 2.19009583193838 bayes_pls_golite062009
structural constituent of ribosome 2.13063800565247 bayes_pls_golite062009
structural molecule activity 1.9177190829469 bayes_pls_golite062009
telomeric DNA binding 1.7847835613194 bayes_pls_golite062009
single-stranded telomeric DNA binding 1.48033977789232 bayes_pls_golite062009
telomerase inhibitor activity 1.25988289474883 bayes_pls_golite062009
DNA helicase activity 1.12203697857261 bayes_pls_golite062009
exoribonuclease activity 1.07725510169091 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.05277881555112 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.79554655100991 bayes_pls_golite062009
RNA polymerase activity 0.79554655100991 bayes_pls_golite062009
transcription regulator activity 0.756094573447167 bayes_pls_golite062009
hydrolase activity 0.724860465280978 bayes_pls_golite062009
DNA-dependent ATPase activity 0.638831894247026 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.592562824942671 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
double-stranded DNA binding 0.378383789953688 bayes_pls_golite062009
nucleotidyltransferase activity 0.325774164899685 bayes_pls_golite062009
translation regulator activity 0.31332179848255 bayes_pls_golite062009
exonuclease activity 0.28313884527829 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.263197317040851 bayes_pls_golite062009
sequence-specific DNA binding 0.21650406007586 bayes_pls_golite062009
translation initiation factor activity 0.2080607201312 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.0954216620147701 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0909806857084046 bayes_pls_golite062009
transcription factor activity 0.0591886273075271 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.0179535526984695 bayes_pls_golite062009
helicase activity 0.0121541775159524 bayes_pls_golite062009

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