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View Structure Prediction Details

Protein: gi|109050845
Organism: Macaca mulatta
Length: 201 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|109050845.

Description E-value Query
Range
Subject
Range
gi|109501290 - gi|109501290|ref|XP_341289.3| PREDICTED: similar to ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homol...
2.0E-63 [1..201] [25..225]
UB2E2_MOUSE - Ubiquitin-conjugating enzyme E2 E2 OS=Mus musculus GN=Ube2e2 PE=2 SV=1
4.0E-63 [1..201] [1..201]
gi|118403846, gi... - gi|118403846|ref|NP_001072140.1| UB2E2 [Sus scrofa], gi|115371731|gb|ABI96190.1| UB2E2 [Sus scrofa]
5.0E-63 [1..201] [1..201]
gi|52354679, gi|... - gi|52354679|gb|AAH82942.1| LOC494805 protein [Xenopus laevis], gi|148233776|ref|NP_001088106.1| hypo...
gi|187607782, gi... - gi|187607782|ref|NP_001119983.1| ubiquitin-conjugating enzyme E2E 2 [Xenopus (Silurana) tropicalis],...
2.0E-62 [1..201] [1..201]
gi|73989346 - gi|73989346|ref|XP_852428.1| PREDICTED: similar to ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolo...
4.0E-60 [1..201] [1..200]
gi|50370097, gi|... - gi|51011079|ref|NP_001003494.1| ubiquitin-conjugating enzyme E2E 2 [Danio rerio], gi|50370097|gb|AAH...
6.0E-58 [1..201] [1..201]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTEAQRVDD SPSTSGGSSD GDQRESVQQE PEREQVQPKK KEGKISSKTA AKLSTSAKRI  60
   61 QKELAEITLD PPPNCSAGPK GDNIYEWRST ILGPPGSVYE GGVFFLDITF SPDYPFKPPK 120
  121 VTFRTRIYHC NINSQGVICL DILKDNWSPA LTISKVLLSI CSLLTDCNPA DPLVGSIATQ 180
  181 YMTNRAEHDR MARQWTKRYA T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.522879
Match: 1y6lA
Description: Human ubiquitin conjugating enzyme E2E2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 11.3486134076304 bayes_pls_golite062009
small conjugating protein ligase activity 11.2964721480824 bayes_pls_golite062009
acid-amino acid ligase activity 10.2401422444624 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 8.93602533934698 bayes_pls_golite062009
ligase activity 5.17219147802758 bayes_pls_golite062009
SUMO ligase activity 3.88357560284404 bayes_pls_golite062009
ISG15 ligase activity 3.37361650623694 bayes_pls_golite062009
HLH domain binding 2.41376652679018 bayes_pls_golite062009
transcription regulator activity 2.21355731489173 bayes_pls_golite062009
nucleic acid binding 2.13970605403492 bayes_pls_golite062009
DNA binding 1.95596447916631 bayes_pls_golite062009
protein binding 1.77678273247394 bayes_pls_golite062009
binding 1.75350658654805 bayes_pls_golite062009
transcription repressor activity 1.5236035191291 bayes_pls_golite062009
transcription activator activity 1.19240180311941 bayes_pls_golite062009
catalytic activity 0.891402822028799 bayes_pls_golite062009
NEDD8 ligase activity 0.715654744941217 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.58835335751383 bayes_pls_golite062009
kinase activity 0.519703305315987 bayes_pls_golite062009
protein kinase activity 0.443948654247666 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.373779304908933 bayes_pls_golite062009
protein serine/threonine kinase activity 0.182854082413338 bayes_pls_golite062009
transcription corepressor activity 0.122859425935324 bayes_pls_golite062009
transferase activity 0.0984525836903841 bayes_pls_golite062009
transcription factor binding 0.0104967529560147 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle