| Protein: | Dscam-PX |
| Organism: | Drosophila melanogaster |
| Length: | 2031 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PX.
| Description | E-value | Query Range |
Subject Range |
|
|
1570.0 | [0..3] | [2031..3] |
|
Region A: Residues: [1-249] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVQQF YESEVNNEYV IRGNAAVLKC SIPSFVADFV QVVSWQDEEG 180
181 QLYGSLGDQQ GTDGKYLVLP SGELHIREVG PEDGYKSYQC RTKHRLTGET RLSATKGRLV 240
241 ITEPIGARA
|
| Detection Method: |  |
| Confidence: | 80.30103 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [250-896] |
1 11 21 31 41 51
| | | | | |
1 PTFSTDSNSF SYTRSVGQSF ALLCQAQAYP VPIMRWYKFI EGTTRKQAVV LNDRVKQVSG 60
61 TLIIKDAVVE DSGKYLCVVN NSVGGESVET VLTVTAPLSA KIDPPTQTVD FGRPAVFTCQ 120
121 YTGNPIKTVS WMKDGKAIGH SEPVLRIESV KKEDKGMYQC FVRNDQESAE ASAELKLGGR 180
181 FDPPVIRQAF QEETMEPGPS VFLKCVAGGN PTPEISWELD GKKIANNDRY QVGQYVTVNG 240
241 DVVSYLNITS VHANDGGLYK CIAKSKVGVA EHSAKLNVYG LPYIRQMEKK AIVAGETLIV 300
301 TCPVAGYPID SIVWERDNRA LPINRKQKVF PNGTLIIENV ERNSDQATYT CVAKNQEGYS 360
361 ARGSLEVQVM ELPQVDQFHF NANGVNGGQA VRVMCMVSSG DLPIDIYWLK DGQPLLRSIY 420
421 HKIDEYTLIL SLRQTTIGDS GNYTCVASNA AGVASRWSIL KVKVPPRWIL EPTDKAFAQG 480
481 SDAKVECKAD GFPKPQVTWK KAVGDTPGEY KDLKKSDNIR VEEGTLHVDN IQKTNEGYYL 540
541 CEAINGIGSG LSAVIMISVQ APPEFTEKLR NQTARRGEPA VLQCEAKGEK PIGILWNMNN 600
601 MRLDPKNDNR YTIREEILST GVMSSLSIKR TERSDSALFT CVATNAF
|
| Detection Method: | |
| Confidence: | 63.0 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [897-1004] |
1 11 21 31 41 51
| | | | | |
1 GSDDASINMI VQEVPEMPYA LKVLDKSGRS VQLSWAQPYD GNSPLDRYII EFKRSRASWS 60
61 EIDRVIVPGH TTEAQVQKLS PATTYNIRIV AENAIGTSQS SEAVTIIT
|
| Detection Method: | |
| Confidence: | 40.39794 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [1005-1112] |
1 11 21 31 41 51
| | | | | |
1 AEEAPSGKPQ NIKVEPVNQT TMRVTWKPPP RTEWNGEILG YYVGYKLSNT NSSYVFETIN 60
61 FITEEGKEHN LELQNLRVYT QYSVVIQAFN KIGAGPLSEE EKQFTAEG
|
| Detection Method: | |
| Confidence: | 12.154902 |
| Match: | 2edxA |
| Description: | No description for 2edxA was found. |
|
Region A: Residues: [1113-1162] |
1 11 21 31 41 51
| | | | | |
1 TPSQPPSDTA CTTLTSQTIR VGWVSPPLES ANGVIKTYKV VYAPSDEWYD
|
| Detection Method: | |
| Confidence: | 2.83 |
| Match: | 2dbjA |
| Description: | No description for 2dbjA was found. |
|
Region A: Residues: [1163-1480] |
1 11 21 31 41 51
| | | | | |
1 ETKRHYKKTA SSDTVLHGLK KYTNYTMQVL ATTAGGDGVR SVPIHCQTEP DVPEAPTDVK 60
61 ALVMGNAAIL VSWRPPAQPN GIITQYTVYS KAEGAETETK TQKVPHYQMS FEATELEKNK 120
121 PYEFWVTAST TIGEGQQSKS IVAMPSDQVP AKIASFDDTF TATFKEDAKM PCLAVGAPQP 180
181 EITWKIKGVE FSANDRMRVL PDGSLLIKSV NRQDAGDYSC HAENSIAKDS ITHKLIVLAP 240
241 PQSPHVTLSA TTTDALTVKL KPHEGDTAPL HGYTLHYKPE FGEWETSEVS VDSQKHNIEG 300
301 LLCGSRYQVY ATGFNNIG
|
| Detection Method: | |
| Confidence: | 17.30103 |
| Match: | 2dtgE |
| Description: | No description for 2dtgE was found. |
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| growth factor binding | 3.39021787583547 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| interleukin-2 binding | 2.38131482184802 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.9781930293417 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.9781930293417 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.07748328484506 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.992216255634359 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.99058387466784 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.817385502041609 | bayes_pls_golite062009 |
| cell surface binding | 0.792329562040096 | bayes_pls_golite062009 |
| heparin binding | 0.7054081997714 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| collagen binding | 0.688581536921572 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.65508836327606 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.536485665371611 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.536485665371611 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transferase activity | 0.432850266451294 | bayes_pls_golite062009 |
| polysaccharide binding | 0.4326581122899 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor binding | 0.338520586013721 | bayes_pls_golite062009 |
| pattern binding | 0.30071837231983 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
|
Region A: Residues: [1481-1598] |
1 11 21 31 41 51
| | | | | |
1 AGEASDILNT RTKGQKPKLP EKPRFIEVSS NSVSLHFKAW KDGGCPMSHF VVESKKRDQI 60
61 EWNQISNNVK PDNNYVVLDL EPATWYNLRI TAHNSAGFTV AEYDFATLTV TGGTIAPL
|
| Detection Method: | |
| Confidence: | 7.0 |
| Match: | 1bquA |
| Description: | Cytokine receptor gp130 cytokine-binding domains |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| growth factor binding | 3.39021787583547 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| interleukin-2 binding | 2.38131482184802 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.9781930293417 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.9781930293417 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.07748328484506 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.992216255634359 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.99058387466784 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.817385502041609 | bayes_pls_golite062009 |
| cell surface binding | 0.792329562040096 | bayes_pls_golite062009 |
| heparin binding | 0.7054081997714 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| collagen binding | 0.688581536921572 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.65508836327606 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.536485665371611 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.536485665371611 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transferase activity | 0.432850266451294 | bayes_pls_golite062009 |
| polysaccharide binding | 0.4326581122899 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor binding | 0.338520586013721 | bayes_pls_golite062009 |
| pattern binding | 0.30071837231983 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
|
Region A: Residues: [1599-1820] |
1 11 21 31 41 51
| | | | | |
1 DDGSGHGNVH TRIRLPAWMP EWLDLNFMVP LIATVVVVAV GICVVCVALS RRRADDMRGG 60
61 QKDVYYDVVY NQTMGPGATL DKRRPDLRDE LGYIAPPNRK LPPVPGSNYN TCDRIKRGRG 120
121 GLRSNHSTWD PRRNPNLYEE LKAPPVPMHG NHYGHAHGNA ECHYRHPGME DEICPYATFH 180
181 LLGFREEMDP TKAMNFQTFP HQNGHAGPVP GHAGTMLPPG HP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1821-2031] |
1 11 21 31 41 51
| | | | | |
1 GHVHSRSGSQ SMPRANRYQR KNSQGGQSSI YTPAPEYDDP ANCAEEDQYR RYTRVNSQGG 60
61 SLYSGPGPEY DDPANCAPEE DQYGSQYGGP YGQPYDHYGS RGSMGRRSIG SARNPGNGSP 120
121 EPPPPPPRNH DMSNSSFNDS KESNEISEAE CDRDHGPRGN YGAVKRSPQP KDQRTTEEMR 180
181 KLIERNETGP KQLQLQQANG AGFTAYDTMA V
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
