






| Protein: | TSG101 |
| Organism: | Homo sapiens |
| Length: | 390 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TSG101.
| Description | E-value | Query Range |
Subject Range |
|
|
2.0E-77 | [1..390] | [1..391] |
|
|
8.0E-77 | [1..390] | [1..391] |
|
|
9.0E-77 | [1..390] | [1..390] |
|
|
3.0E-76 | [1..390] | [1..390] |
|
|
2.0E-74 | [4..390] | [377..763] |
|
|
7.0E-74 | [1..390] | [1..391] |
|
Region A: Residues: [1-194] |
1 11 21 31 41 51
| | | | | |
1 MAVSESQLKK MVSKYKYRDL TVRETVNVIT LYKDLKPVLD SYVFNDGSSR ELMNLTGTIP 60
61 VPYRGNTYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP 120
121 QSDLLGLIQV MIVVFGDEPP VFSRPISASY PPYQATGPPN TSYMPGMPGG ISPYPSGYPP 180
181 NPSGYPGCPY PPGG
|
| Detection Method: | |
| Confidence: | 46.39794 |
| Match: | 1kppA |
| Description: | Tumor susceptibility gene 101 (TSG101) UEV domain |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| small conjugating protein ligase activity | 6.80727357703118 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 6.75330204125607 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 5.83782824833863 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.8110076681004 | bayes_pls_golite062009 |
| transcription regulator activity | 2.21355731489173 | bayes_pls_golite062009 |
| nucleic acid binding | 2.13970605403492 | bayes_pls_golite062009 |
| DNA binding | 1.95596447916631 | bayes_pls_golite062009 |
| ligase activity | 1.88059319399119 | bayes_pls_golite062009 |
| binding | 1.75350658654805 | bayes_pls_golite062009 |
| transcription repressor activity | 1.5236035191291 | bayes_pls_golite062009 |
| catalytic activity | 0.891402822028799 | bayes_pls_golite062009 |
| SUMO ligase activity | 0.843488104298821 | bayes_pls_golite062009 |
| protein binding | 0.726328463755484 | bayes_pls_golite062009 |
| NEDD8 ligase activity | 0.715654744941217 | bayes_pls_golite062009 |
| protein kinase activity | 0.443948654247666 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.182854082413338 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.133142640608253 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.122859425935324 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.0501858755083694 | bayes_pls_golite062009 |
| kinase activity | 0.0500350353657541 | bayes_pls_golite062009 |
| transcription activator activity | 0.0138208971172455 | bayes_pls_golite062009 |
| transcription factor binding | 0.0104967529560147 | bayes_pls_golite062009 |
|
Region A: Residues: [195-390] |
1 11 21 31 41 51
| | | | | |
1 PYPATTSSQY PSQPPVTTVG PSRDGTISED TIRASLISAV SDKLRWRMKE EMDRAQAELN 60
61 ALKRTEEDLK KGHQKLEEMV TRLDQEVAEV DKNIELLKKK DEELSSALEK MENQSENNDI 120
121 DEVIIPTAPL YKQILNLYAE ENAIEDTIFY LGEALRRGVI DLDVFLKHVR LLSRKQFQLR 180
181 ALMQKARKTA GLSDLY
|
| Detection Method: | |
| Confidence: | 23.522879 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB):![]() |
|