| Protein: | TRPC4 |
| Organism: | Homo sapiens |
| Length: | 977 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRPC4.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..977] | [1..977] |
|
|
0.0 | [1..977] | [1..977] |
|
|
0.0 | [1..977] | [3..981] |
|
|
0.0 | [20..977] | [1..958] |
|
Region A: Residues: [1-285] |
1 11 21 31 41 51
| | | | | |
1 MAQFYYKRNV NAPYRDRIPL RIVRAESELS PSEKAYLNAV EKGDYASVKK SLEEAEIYFK 60
61 ININCIDPLG RTALLIAIEN ENLELIELLL SFNVYVGDAL LHAIRKEVVG AVELLLNHKK 120
121 PSGEKQVPPI LLDKQFSEFT PDITPIILAA HTNNYEIIKL LVQKGVSVPR PHEVRCNCVE 180
181 CVSSSDVDSL RHSRSRLNIY KALASPSLIA LSSEDPFLTA FQLSWELQEL SKVENEFKSE 240
241 YEELSRQCKQ FAKDLLDQTR SSRELEIILN YRDDNSLIEE QSGND
|
| Detection Method: |  |
| Confidence: | 17.39794 |
| Match: | 2fo1E |
| Description: | No description for 2fo1E was found. |
|
Region A: Residues: [286-357] |
1 11 21 31 41 51
| | | | | |
1 LARLKLAIKY RQKEFVAQPN CQQLLASRWY DEFPGWRRRH WAVKMVTCFI IGLLFPVFSV 60
61 CYLIAPKSPL GL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [358-692] |
1 11 21 31 41 51
| | | | | |
1 FIRKPFIKFI CHTASYLTFL FLLLLASQHI DRSDLNRQGP PPTIVEWMIL PWVLGFIWGE 60
61 IKQMWDGGLQ DYIHDWWNLM DFVMNSLYLA TISLKIVAFV KYSALNPRES WDMWHPTLVA 120
121 EALFAIANIF SSLRLISLFT ANSHLGPLQI SLGRMLLDIL KFLFIYCLVL LAFANGLNQL 180
181 YFYYEETKGL TCKGIRCEKQ NNAFSTLFET LQSLFWSIFG LINLYVTNVK AQHEFTEFVG 240
241 ATMFGTYNVI SLVVLLNMLI AMMNNSYQLI ADHADIEWKF ARTKLWMSYF EEGGTLPTPF 300
301 NVIPSPKSLW YLIKWIWTHL CKKKMRRKPE SFGTI
|
| Detection Method: | |
| Confidence: | 23.154902 |
| Match: | 2a79B |
| Description: | Mammalian Shaker Kv1.2 potassium channel- beta subunit complex |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [693-761] |
1 11 21 31 41 51
| | | | | |
1 GRRAADNLRR HHQYQEVMRN LVKRYVAAMI RDAKTEEGLT EENFKELKQD ISSFRFEVLG 60
61 LLRGSKLST
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [762-977] |
1 11 21 31 41 51
| | | | | |
1 IQSANASKES SNSADSDEKS DSEGNSKDKK KNFSLFDLTT LIHPRSAAIA SERHNISNGS 60
61 ALVVQEPPRE KQRKVNFVTD IKNFGLFHRR SKQNAAEQNA NQIFSVSEEV ARQQAAGPLE 120
121 RNIQLESRGL ASRGDLSIPG LSEQCVLVDH RERNTDTLGL QVGKRVCPFK SEKVVVEDTV 180
181 PIIPKEKHAK EEDSSIDYDL NLPDTVTHED YVTTRL
|
| Detection Method: | |
| Confidence: | 5.30103 |
| Match: | 1q33A |
| Description: | Crystal structure of human ADP-ribose pyrophosphatase NUDT9 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| metal ion transmembrane transporter activity | 3.14284918783319 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.77672397171221 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.76658625373154 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.55165879409032 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.23934826890513 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.23707606020328 | bayes_pls_golite062009 |
| cation channel activity | 2.02327029328545 | bayes_pls_golite062009 |
| manganese ion transmembrane transporter activity | 2.01178023504656 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 1.73151832826112 | bayes_pls_golite062009 |
| pyrophosphatase activity | 1.60956352556846 | bayes_pls_golite062009 |
| ion channel activity | 1.49956611721119 | bayes_pls_golite062009 |
| channel activity | 1.45389648555252 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 1.45389648555252 | bayes_pls_golite062009 |
| substrate-specific channel activity | 1.44857305885791 | bayes_pls_golite062009 |
| hydrolase activity | 1.36927203866255 | bayes_pls_golite062009 |
| transporter activity | 1.26144641115218 | bayes_pls_golite062009 |
| transition metal ion transmembrane transporter activity | 1.19048684580333 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.06120201707805 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.842503783075326 | bayes_pls_golite062009 |
| calcium channel activity | 0.795261805936657 | bayes_pls_golite062009 |
| binding | 0.770007304343682 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.549441354164187 | bayes_pls_golite062009 |
| di-, tri-valent inorganic cation transmembrane transporter activity | 0.333193584681061 | bayes_pls_golite062009 |
| protein binding | 0.0150710541177431 | bayes_pls_golite062009 |
