| Protein: | HDAC1 |
| Organism: | Homo sapiens |
| Length: | 482 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HDAC1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..482] | [1..480] |
|
|
0.0 | [1..482] | [1..482] |
|
|
0.0 | [1..481] | [1..486] |
|
|
0.0 | [1..445] | [1..445] |
|
|
0.0 | [1..478] | [95..577] |
|
Region A: Residues: [1-379] |
1 11 21 31 41 51
| | | | | |
1 MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN 60
61 AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS 120
121 AVKLNKQQTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG 180
181 DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI 240
241 FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG 300
301 GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE 360
361 KIKQRLFENL RMLPHAPGV
|
| Detection Method: |  |
| Confidence: | 102.0 |
| Match: | 1t64A |
| Description: | Crystal Structure of human HDAC8 complexed with Trichostatin A |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein deacetylase activity | 12.8220438463909 | bayes_pls_golite062009 |
| histone deacetylase activity | 12.6231784270509 | bayes_pls_golite062009 |
| deacetylase activity | 11.5037545953213 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 9.39837596691907 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 5.91624581343504 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K16 specific) | 4.36879207064621 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K27 specific) | 3.8227021325477 | bayes_pls_golite062009 |
| agmatinase activity | 3.73238467801147 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K9 specific) | 3.65015413158247 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K14 specific) | 3.59362549089403 | bayes_pls_golite062009 |
| transcription repressor activity | 3.49362347258099 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| transcription regulator activity | 3.05701986980927 | bayes_pls_golite062009 |
| hydrolase activity | 2.48411098726406 | bayes_pls_golite062009 |
| transcription factor binding | 2.19991964087943 | bayes_pls_golite062009 |
| nucleic acid binding | 2.09632179671955 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.98907367314887 | bayes_pls_golite062009 |
| DNA binding | 1.982290944939 | bayes_pls_golite062009 |
| binding | 1.948738669065 | bayes_pls_golite062009 |
| protein binding | 1.77599011146146 | bayes_pls_golite062009 |
| catalytic activity | 1.68836803454021 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K9 specific) | 1.48241147541212 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 1.37118634909958 | bayes_pls_golite062009 |
| arginase activity | 1.34373529002692 | bayes_pls_golite062009 |
| transcription factor activity | 1.24596588472933 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | 1.01223037319069 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84972377395539 | bayes_pls_golite062009 |
| histone methyltransferase activity | 0.396822865624511 | bayes_pls_golite062009 |
| transferase activity | 0.323230424038105 | bayes_pls_golite062009 |
| chromatin binding | 0.104097933861351 | bayes_pls_golite062009 |
|
Region A: Residues: [380-482] |
1 11 21 31 41 51
| | | | | |
1 QMQAIPEDAI PEESGDEDED DPDKRISICS SDKRIACEEE FSDSEEEGEG GRKNSSNFKK 60
61 AKRVKTEDEK EKDPEEKKEV TEEEKTKEEK PEAKGVKEEV KLA
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
