| Protein: | NTHL1 |
| Organism: | Homo sapiens |
| Length: | 312 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NTHL1.
| Description | E-value | Query Range |
Subject Range |
|
|
6.0E-67 | [1..312] | [1..312] |
|
|
3.0E-66 | [1..312] | [1..312] |
|
|
4.0E-60 | [15..312] | [6..300] |
|
|
1.0E-59 | [103..312] | [3..209] |
|
|
1.0E-59 | [103..311] | [3..208] |
|
|
2.0E-59 | [103..310] | [5..209] |
|
|
2.0E-59 | [15..312] | [6..300] |
|
Region A: Residues: [1-88] |
1 11 21 31 41 51
| | | | | |
1 MCSPQESGMT ALSARMLTRS RSLGPGAGPR GCREEPGPLR RREAAAEARK SHSPVKRPRK 60
61 AQRLRVAYEG SDSEKGEGAE PLKVPVWE
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [89-312] |
1 11 21 31 41 51
| | | | | |
1 PQDWQQQLVN IRAMRNKKDA PVDHLGTEHC YDSSAPPKVR RYQVLLSLML SSQTKDQVTA 60
61 GAMQRLRARG LTVDSILQTD DATLGKLIYP VGFWRSKVKY IKQTSAILQQ HYGGDIPASV 120
121 AELVALPGVG PKMAHLAMAV AWGTVSGIAV DTHVHRIANR LRWTKKATKS PEETRAALEE 180
181 WLPRELWHEI NGLLVGFGQQ TCLPVHPRCH ACLNQALCPA AQGL
|
| Detection Method: | |
| Confidence: | 60.30103 |
| Match: | 2abkA |
| Description: | REFINEMENT OF THE NATIVE STRUCTURE OF ENDONUCLEASE III TO A RESOLUTION OF 1.85 ANGSTROM |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA N-glycosylase activity | 4.8124964619976 | bayes_pls_golite062009 |
| hydrolase activity, hydrolyzing N-glycosyl compounds | 4.26870112679392 | bayes_pls_golite062009 |
| DNA-(apurinic or apyrimidinic site) lyase activity | 3.71152530486175 | bayes_pls_golite062009 |
| oxidized base lesion DNA N-glycosylase activity | 2.49872706126491 | bayes_pls_golite062009 |
| hydrolase activity | 2.39042189031819 | bayes_pls_golite062009 |
| 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity | 2.21048599823382 | bayes_pls_golite062009 |
| hydrolase activity, acting on glycosyl bonds | 2.18053745735048 | bayes_pls_golite062009 |
| catalytic activity | 2.13345932727422 | bayes_pls_golite062009 |
| damaged DNA binding | 2.00388798014411 | bayes_pls_golite062009 |
| alkylbase DNA N-glycosylase activity | 1.5832578018127 | bayes_pls_golite062009 |
| DNA binding | 1.44394874535958 | bayes_pls_golite062009 |
| nucleic acid binding | 1.36800347239439 | bayes_pls_golite062009 |
| oxidized purine base lesion DNA N-glycosylase activity | 1.32985950765371 | bayes_pls_golite062009 |
| oxidized pyrimidine base lesion DNA N-glycosylase activity | 1.2016453685638 | bayes_pls_golite062009 |
| binding | 1.15752946565805 | bayes_pls_golite062009 |
| DNA-3-methyladenine glycosylase I activity | 1.06383943982125 | bayes_pls_golite062009 |
| uracil DNA N-glycosylase activity | 0.879508131574476 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.85419760398899 | bayes_pls_golite062009 |
| purine-specific mismatch base pair DNA N-glycosylase activity | 0.68578837518217 | bayes_pls_golite062009 |
| mismatch base pair DNA N-glycosylase activity | 0.661651574677137 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.57099109384393 | bayes_pls_golite062009 |
| transcription regulator activity | 0.493252955870142 | bayes_pls_golite062009 |
| protein binding | 0.0921713980805489 | bayes_pls_golite062009 |
| carbon-oxygen lyase activity | 0.0676784802238829 | bayes_pls_golite062009 |
