GO TERM SUMMARY
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Name: |
DNA-3-methyladenine glycosylase I activity |
Acc: |
GO:0008725 |
Aspect: |
Molecular Function |
Desc: |
Catalysis of the hydrolysis of alkylated DNA; only recognizes and removes the alkylated base 3-methyladenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site. |
Synonyms:
- DNA glycosidase I activity
- deoxyribonucleate 3-methyladenine glycosidase I
- alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
- DNA-3-methyladenine glycosidase I activity
- 3-methyladenine DNA glycosylase I
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