| Protein: | GAL4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 881 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAL4.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..881] | [1..881] |
|
|
5.0E-86 | [3..742] | [61..810] |
|
|
3.0E-84 | [4..752] | [32..731] |
|
|
2.0E-83 | [3..820] | [23..807] |
|
|
8.0E-83 | [3..822] | [53..787] |
|
|
3.0E-80 | [2..821] | [61..834] |
|
Region A: Residues: [1-65] |
1 11 21 31 41 51
| | | | | |
1 MKLLSSIEQA CDICRLKKLK CSKEKPKCAK CLKNNWECRY SPKTKRSPLT RAHLTEVESR 60
61 LERLE
|
| Detection Method: |  |
| Confidence: | 335.31133 |
| Match: | 1d66A_ |
| Description: | Gal4; CD2-Gal4 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.56444258780502 | bayes_pls_golite062009 |
| DNA binding | 4.26146437716972 | bayes_pls_golite062009 |
| nucleic acid binding | 4.17369933547911 | bayes_pls_golite062009 |
| transcription factor activity | 3.049435548132 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.98081393153291 | bayes_pls_golite062009 |
| binding | 2.91929847152301 | bayes_pls_golite062009 |
| transcription activator activity | 2.24483536326713 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.03201524223606 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.86200506906385 | bayes_pls_golite062009 |
|
Region A: Residues: [66-125] |
1 11 21 31 41 51
| | | | | |
1 QLFLLIFPRE DLDMILKMDS LQDIKALLTG LFVQDNVNKD AVTDRLASVE TDMPLTLRQH 60
61
|
| Detection Method: | |
| Confidence: | 18.958607 |
| Match: | PF03902 |
| Description: | Gal4-like dimerisation domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| transcription regulator activity | 4.34861813464065 | bayes_pls_golite062009 |
| DNA binding | 4.03985756894684 | bayes_pls_golite062009 |
| nucleic acid binding | 3.97978190843512 | bayes_pls_golite062009 |
| transcription factor activity | 2.87348461329489 | bayes_pls_golite062009 |
| binding | 2.82809978070212 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.77469997789536 | bayes_pls_golite062009 |
| transcription activator activity | 2.1512787242583 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.80191339934741 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.50774349911815 | bayes_pls_golite062009 |
|
Region A: Residues: [126-491] |
1 11 21 31 41 51
| | | | | |
1 RISATSSSEE SSNKGQRQLT VSIDSAAHHD NSTIPLDFMP RDALHGFDWS EEDDMSDGLP 60
61 FLKTDPNNNG FFGDGSLLCI LRSIGFKPEN YTNSNVNRLP TMITDRYTLA SRSTTSRLLQ 120
121 SYLNNFHPYC PIVHSPTLMM LYNNQIEIAS KDQWQILFNC ILAIGAWCIE GESTDIDVFY 180
181 YQNAKSHLTS KVFESGSIIL VTALHLLSRY TQWRQKTNTS YNFHSFSIRM AISLGLNRDL 240
241 PSSFSDSSIL EQRRRIWWSV YSWEIQLSLL YGRSIQLSQN TISFPSSVDD VQRTTTGPTI 300
301 YHGIIETARL LQVFTKIYEL DKTVTAEKSP ICAKKCLMIC NEIEEVSRQA PKFLQMDIST 360
361 TALTNL
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [492-597] |
1 11 21 31 41 51
| | | | | |
1 LKEHPWLSFT RFELKWKQLS LIIYVLRDFF TNFTQKKSQL EQDQNDHQSY EVKRCSIMLS 60
61 DAAQRTVMSV SSYMDNHNVT PYFAWNCSYY LFNAVLVPIK TLLSNS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.875 | 0.004 | galactose metabolic process | f.18.1 | F1F0 ATP synthase subunit A |
|
Region A: Residues: [598-881] |
1 11 21 31 41 51
| | | | | |
1 KSNAENNETA QLLQQINTVL MLLKKLATFK IQTCEKYIQV LEEVCAPFLL SQCAIPLPHI 60
61 SYNNSNGSAI KNIVGSATIA QYPTLPEENV NNISVKYVSP GSVGPSPVPL KSGASFSDLV 120
121 KLLSNRPPSR NSPVTIPRST PSHRSVTPFL GQQQQLQSLV PLTPSALFGG ANFNQSGNIA 180
181 DSSLSFTFTN SSNGPNLITT QTNSQALSQP IASSNVHDNF MNNEITASKI DDGNNSKPLS 240
241 PGWTDQTAYN AFGITTGMFN TTTMDDVYNY LFDDEDTPPN PKKE
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [655-778] |
1 11 21 31 41 51
| | | | | |
1 PHISYNNSNG SAIKNIVGSA TIAQYPTLPE ENVNNISVKY VSPGSVGPSP VPLKSGASFS 60
61 DLVKLLSNRP PSRNSPVTIP RSTPSHRSVT PFLGQQQQLQ SLVPLTPSAL FGGANFNQSG 120
121 NIAD
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [779-881] |
1 11 21 31 41 51
| | | | | |
1 SSLSFTFTNS SNGPNLITTQ TNSQALSQPI ASSNVHDNFM NNEITASKID DGNNSKPLSP 60
61 GWTDQTAYNA FGITTGMFNT TTMDDVYNYL FDDEDTPPNP KKE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
