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View Structure Prediction Details

Protein: BMS1
Organism: Saccharomyces cerevisiae
Length: 1183 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BMS1.

Description E-value Query
Range
Subject
Range
BMS1 - GTPase required for synthesis of 40S ribosomal subunits and for processing the 35S pre-rRNA at sites...
BMS1_YEAST - Ribosome biogenesis protein BMS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BMS1 PE...
gi|190407746 - gi|190407746|gb|EDV11011.1| ribosome biogenesis protein BMS1 [Saccharomyces cerevisiae RM11-1a]
0.0 [1..1183] [1..1183]
BMS1_SCHPO - Ribosome biogenesis protein bms1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=bms1 PE=1...
bms1 - GTP binding protein Bms1
0.0 [2..1182] [5..1120]
gi|85079318 - gi|85079318|ref|XP_956329.1| hypothetical protein NCU04348 [Neurospora crassa OR74A]
gi|28917388, gi|... - gi|32406176|ref|XP_323701.1| hypothetical protein [Neurospora crassa], gi|28917388|gb|EAA27093.1| hy...
0.0 [3..1182] [5..1160]
CG7728-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7728 (CG7728, FBgn0036686). It is a protein...
gi|220947318 - gi|220947318|gb|ACL86202.1| CG7728-PA [synthetic construct]
0.0 [1..1169] [20..1159]
gi|15222176 - gi|15222176|ref|NP_172157.1| unknown protein [Arabidopsis thaliana]
0.0 [4..1174] [9..1145]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [4..1174] [9..1136]
gi|21410151 - gi|21410151|gb|AAH30906.1| Bms1 protein [Mus musculus]
0.0 [338..1178] [93..934]
gi|82541213 - gi|82541213|ref|XP_724863.1| hypothetical protein [Plasmodium yoelii yoelii str. 17XNL]
gi|23479662 - gi|23479662|gb|EAA16428.1| hypothetical protein [Plasmodium yoelii yoelii]
0.0 [2..1164] [5..1211]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQSNKQHRK AKEKNTAKKK LHTQGHNAKA FAVAAPGKMA RTMQRSSDVN ERKLHVPMVD  60
   61 RTPEDDPPPF IVAVVGPPGT GKTTLIRSLV RRMTKSTLND IQGPITVVSG KHRRLTFLEC 120
  121 PADDLNAMID IAKIADLVLL LIDGNFGFEM ETMEFLNIAQ HHGMPRVLGV ATHL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.43368780168847 bayes_pls_golite062009
motor activity 1.66001460462062 bayes_pls_golite062009
RNA binding 1.64085862208961 bayes_pls_golite062009
structural constituent of ribosome 1.58614825683861 bayes_pls_golite062009
microtubule motor activity 1.51492936494661 bayes_pls_golite062009
1.40793830270505 bayes_pls_golite062009
nucleic acid binding 1.38653949159874 bayes_pls_golite062009
RNA helicase activity 1.19425264627559 bayes_pls_golite062009
RNA-dependent ATPase activity 1.16223608981327 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.13639104386803 bayes_pls_golite062009
DNA binding 1.10928092522596 bayes_pls_golite062009
transcription regulator activity 1.02050154675732 bayes_pls_golite062009
cytoskeletal protein binding 1.01452238670999 bayes_pls_golite062009
catalytic activity 0.942640875796745 bayes_pls_golite062009
structural molecule activity 0.675553718290749 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.661839640945953 bayes_pls_golite062009
hydrolase activity 0.59573424609875 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 0.561205936947495 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 0.561205936947495 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 0.560259345938113 bayes_pls_golite062009
tubulin binding 0.486290099514671 bayes_pls_golite062009
protein binding 0.409258528033042 bayes_pls_golite062009
helicase activity 0.389068221426991 bayes_pls_golite062009
microtubule binding 0.379674198622762 bayes_pls_golite062009
actin binding 0.332654682400232 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.191068703418711 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.188196054823553 bayes_pls_golite062009
pyrophosphatase activity 0.184212465168396 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.147137984163853 bayes_pls_golite062009
transcription factor activity 0.0836981407579493 bayes_pls_golite062009
microfilament motor activity 0.0684601046679916 bayes_pls_golite062009
ATP-dependent helicase activity 0.0655945570748848 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.0655945570748848 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [175-329]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLFKSQSTLR ASKKRLKHRF WTEVYQGAKL FYLSGVINGR YPDREILNLS RFISVMKFRP  60
   61 LKWRNEHPYM LADRFTDLTH PELIETQGLQ IDRKVAIYGY LHGTPLPSAP GTRVHIAGVG 120
  121 DFSVAQIEKL PDPCPTPFYQ QKLDDFEREK MKEEA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [330-693]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KANGEITTAS TTRRRKRLDD KDKLIYAPMS DVGGVLMDKD AVYIDIGKKN EEPSFVPGQE  60
   61 RGEGEKLMTG LQSVEQSIAE KFDGVGLQLF SNGTELHEVA DHEGMDVESG EESIEDDEGK 120
  121 SKGRTSLRKP RIYGKPVQEE DADIDNLPSD EEPYTNDDDV QDSEPRMVEI DFNNTGEQGA 180
  181 EKLALETDSE FEESEDEFSW ERTAANKLKK TESKKRTWNI GKLIYMDNIS PEECIRRWRG 240
  241 EDDDSKDESD IEEDVDDDFF RKKDGTVTKE GNKDHAVDLE KFVPYFDTFE KLAKKWKSVD 300
  301 AIKERFLGAG ILGNDNKTKS DSNEGGEELY GDFEDLEDGN PSEQAEDNSD KESEDEDENE 360
  361 DTNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [694-982]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDNSFTNFD AEEKKDLTME QEREMNAAKK EKLRAQFEIE EGENFKEDDE NNEYDTWYEL  60
   61 QKAKISKQLE INNIEYQEMT PEQRQRIEGF KAGSYVRIVF EKVPMEFVKN FNPKFPIVMG 120
  121 GLLPTEIKFG IVKARLRRHR WHKKILKTND PLVLSLGWRR FQTLPIYTTT DSRTRTRMLK 180
  181 YTPEHTYCNA AFYGPLCSPN TPFCGVQIVA NSDTGNGFRI AATGIVEEID VNIEIVKKLK 240
  241 LVGFPYKIFK NTAFIKDMFS SAMEVARFEG AQIKTVSGIR GEIKRALSK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [983-1096]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEGHYRAAFE DKILMSDIVI LRSWYPVRVK KFYNPVTSLL LKEKTEWKGL RLTGQIRAAM  60
   61 NLETPSNPDS AYHKIERVER HFNGLKVPKA VQKELPFKSQ IHQMKPQKKK TYMA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.495 0.430 ribosome assembly a.1.1 Globin-like
View Download 0.499 0.086 ribosome assembly a.118.8 TPR-like
View Download 0.414 0.041 ribosome assembly d.95.2 Homing endonucleases
View Download 0.379 N/A N/A d.53.1 Ribosomal protein S3 C-terminal domain
View Download 0.347 N/A N/A d.206.1 YggU-like
View Download 0.337 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.305 N/A N/A a.47.2 t-snare proteins
View Download 0.290 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.264 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.261 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.244 N/A N/A a.46.1 Methionine synthase domain
View Download 0.237 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.237 N/A N/A a.74.1 Cyclin-like
View Download 0.236 N/A N/A d.74.4 Prokaryotic AspRS, insert domain
View Download 0.235 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.230 N/A N/A c.84.1 Phosphoglucomutase, first 3 domains
View Download 0.227 N/A N/A a.1.1 Globin-like
View Download 0.220 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.219 N/A N/A c.45.1 (Phosphotyrosine protein) phosphatases II

Predicted Domain #6
Region A:
Residues: [1097-1183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRAVVLGGDE KKARSFIQKV LTISKAKDSK RKEQKASQRK ERLKKLAKME EEKSQRDKEK  60
   61 KKEYFAQNGK RTTMGGDDES RPRKMRR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.796 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.714 a.47.2 t-snare proteins
View Download 0.469 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.711 a.24.17 Group V grass pollen allergen
View Download 0.544 a.46.1 Methionine synthase domain
View Download 0.462 a.7.5 Tubulin chaperone cofactor A
View Download 0.452 a.7.6 Ribosomal protein S20
View Download 0.447 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.400 a.112.1 Description not found.
View Download 0.398 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.389 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.369 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.346 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.340 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.332 a.24.3 Cytochromes
View Download 0.331 d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.328 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.325 g.2.2 Neurotoxin B-IV
View Download 0.322 a.64.1 Saposin
View Download 0.321 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.317 a.7.7 BAG domain
View Download 0.308 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.307 i.1.1 Ribosome and ribosomal fragments
View Download 0.306 a.7.8 GAT domain
View Download 0.303 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.302 a.4.5 "Winged helix" DNA-binding domain
View Download 0.301 a.71.2 Helical domain of Sec23/24
View Download 0.288 a.2.3 Chaperone J-domain
View Download 0.288 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.278 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.278 d.95.2 Homing endonucleases
View Download 0.273 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.265 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.259 a.22.1 Histone-fold
View Download 0.257 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.254 a.25.1 Ferritin-like
View Download 0.254 a.17.1 p8-MTCP1
View Download 0.252 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.250 f.15.1 Small-conductance potassium channel
View Download 0.249 a.126.1 Serum albumin-like
View Download 0.240 a.24.17 Group V grass pollen allergen
View Download 0.238 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.232 a.47.2 t-snare proteins
View Download 0.230 a.29.4 RecG, N-terminal domain
View Download 0.229 a.59.1 PAH2 domain
View Download 0.228 a.2.5 Prefoldin
View Download 0.228 a.2.7 tRNA-binding arm
View Download 0.227 a.61.1 Retroviral matrix proteins
View Download 0.211 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.210 a.24.4 Hemerythrin
View Download 0.205 a.39.1 EF-hand
View Download 0.205 a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.201 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle