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View Structure Prediction Details

Protein: PNG1
Organism: Saccharomyces cerevisiae
Length: 363 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNG1.

Description E-value Query
Range
Subject
Range
PNG1_YEAST - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Saccharomyces cerevisiae (strain ATCC...
PNG1 - Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteas...
gi|190407860 - gi|190407860|gb|EDV11125.1| peptide:N-glycanase [Saccharomyces cerevisiae RM11-1a]
gi|151942701 - gi|151942701|gb|EDN61047.1| PNGase [Saccharomyces cerevisiae YJM789]
0.0 [1..363] [1..363]
NGLY1 - N-glycanase 1
gi|123993667, gi... - gi|123999983|gb|ABM87500.1| N-glycanase 1 [synthetic construct], gi|123993667|gb|ABM84435.1| N-glyca...
0.0 [46..362] [165..473]
NGLY1_MOUSE - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Mus musculus GN=Ngly1 PE=1 SV=2
0.0 [46..362] [162..470]
PNG1_ORYSA - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (Peptide:N-glycanase) - Or...
PNG1_ORYSJ - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Oryza sativa subsp. japonica GN=PNG1 ...
6.0E-99 [13..357] [104..429]
gi|27808626 - gi|27808626|gb|AAO24593.1| At5g49570 [Arabidopsis thaliana]
1.0E-97 [13..362] [89..418]
png-1 - Thioredoxins status:Confirmed UniProt:Q9TW67 protein_id:CAB57916.1
4.0E-90 [52..363] [124..424]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEVYEKNNI DFDSIAKMLL IKYKDFILSK FKKAAPVENI RFQNLVHTNQ FAQGVLGQSQ  60
   61 HLCTVYDNPS WHSIVLETLD LDLIYKNVDK EFAKDGHAEG ENIYTDYLVK ELLRYFKQDF 120
  121 FKWCNKPDCN HCG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
cysteine-type peptidase activity 3.05412701733177 bayes_pls_golite062009
peptidase activity 2.99092799770282 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.70509346529146 bayes_pls_golite062009
binding 2.49172648273202 bayes_pls_golite062009
hydrolase activity 2.29464693834116 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.90904708303381 bayes_pls_golite062009
endopeptidase activity 1.64915398352449 bayes_pls_golite062009
SUMO-specific protease activity 1.44953547163733 bayes_pls_golite062009
nucleic acid binding 1.38318152877128 bayes_pls_golite062009
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity 1.3714358594696 bayes_pls_golite062009
transcription regulator activity 1.34325826373515 bayes_pls_golite062009
DNA binding 1.31096468235949 bayes_pls_golite062009
ubiquitin-specific protease activity 1.28746642057417 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.774177093888744 bayes_pls_golite062009
transcription factor activity 0.656405451523439 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.218846845851145 bayes_pls_golite062009
calcium-dependent cysteine-type endopeptidase activity 0.196538841514154 bayes_pls_golite062009
transferase activity 0.0852393573521809 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [134-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNTSENMTPL GSQGPNGEES KFNCGTVEIY KCNRCGNITR FPRYNDPIKL LETRKGRCGE  60
   61 WCNLFTLILK SFGLDVRYVW NREDHVWCEY FSNFLNRWVH VDSCEQSFDQ PYIYSINWNK 120
  121 KMSYCIAFGK DGVVDVSKRY ILQN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 15.443697
Match: PF01841
Description: Transglutaminase-like superfamily

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [278-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELPRDQIKEE DLKFLCQFIT KRLRYSLNDD EIYQLACRDE QEQIELIRGK TQETKSESVS  60
   61 AASKSSNRGR ESGSADWKAQ RGEDGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle